Detailed information NTG0404918

Bioinformatically predicted

Overview

• Name: micB
• Type: Regulator
• Locus tag: GOM48_RS05410
• Genome accession: NZ_CP046523
• Coordinates: 1070239..1071588 (-)
• Length: 449 a.a.
• NCBI ID: WP_235096359.1
• Uniprot ID: -
• Organism: Streptococcus oralis strain SOD
• Function: repress competence development (predicted from homology) Competence regulation

Genomic Context

Location: 1065239..1076588

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
GOM48_RS05395 (GOM48_05415)	-	1067215..1068933 (+)	1719	WP_235096356.1	phospho-sugar mutase	-
GOM48_RS05400 (GOM48_05420)	-	1069044..1069391 (+)	348	WP_235096357.1	thioredoxin	-
GOM48_RS05405 (GOM48_05425)	vicX	1069428..1070237 (-)	810	WP_235096358.1	MBL fold metallo-hydrolase	Regulator
GOM48_RS05410 (GOM48_05430)	micB	1070239..1071588 (-)	1350	WP_235096359.1	cell wall metabolism sensor histidine kinase VicK	Regulator
GOM48_RS05415 (GOM48_05435)	micA	1071581..1072288 (-)	708	WP_235096360.1	response regulator YycF	Regulator
GOM48_RS05420 (GOM48_05440)	mutY	1072345..1073523 (-)	1179	WP_235096361.1	A/G-specific adenine glycosylase	-
GOM48_RS05425 (GOM48_05445)	pta	1073612..1074586 (-)	975	WP_000451592.1	phosphate acetyltransferase	-
GOM48_RS05430 (GOM48_05450)	-	1074630..1075526 (-)	897	WP_235096362.1	RluA family pseudouridine synthase	-
GOM48_RS05435 (GOM48_05455)	-	1075523..1076341 (-)	819	WP_223326689.1	NAD kinase	-

Sequence

Protein

• Length: 449 a.a.
• Molecular weight: 51651.19 Da
• Isoelectric Point: 4.6821

>NTDB_id=404918 GOM48_RS05410 WP_235096359.1 1070239..1071588(-) (micB) [Streptococcus oralis strain SOD]
MIEDIRQTILTSDFIFILILLGFILVVTLLLLENRRDNIRLKQINQKVKDLIAGDYSRVLDMQGSSEITNITNNLNDLSE
VIRLTQENLEQETKRLNSILSYMTDGVLATNRRGQITMINDMAKKQLGIVKEEALNKSILELLKIEDEYELRDLITQIPE
LMIDSQNANGEYLSLRVRFALIRRESGFISGLVAVLHDTTEQEKEERERRLFVSNVSHELRTPLTSVKSYLEALDEGALY
DPVAPDFIKVSLDETNRMMRMVTDLLHLSRIDNATTQLDVELINFTAFITFILNRFDKMRSQDEEKKYELVRDYPINSVW
IEIDTDKMTQVIDNILNNAIKYSPDGGKITVSMKTTEDQMILSIKDQGLGIPKQDLPKIFDRFYRVDRARSRAQGGTGLG
LAIAKEIIKQHNGFIWAKSEYGKGSTFTIVLPYDKDAVKEEIWEDEIED

Nucleotide

• Length: 1350 bp

>NTDB_id=404918 GOM48_RS05410 WP_235096359.1 1070239..1071588(-) (micB) [Streptococcus oralis strain SOD]
ATGATTGAAGATATTAGACAAACGATTCTGACCAGTGATTTTATCTTTATCCTGATTTTACTTGGCTTTATCTTGGTGGT
AACCTTGTTGTTACTGGAAAATCGTCGGGATAATATTCGGCTAAAGCAGATTAATCAAAAGGTCAAGGATTTGATTGCAG
GGGATTATTCTCGAGTTTTGGATATGCAAGGAAGCTCTGAAATCACCAACATCACCAATAATCTTAATGACTTGTCTGAG
GTCATTCGTCTAACGCAGGAAAATCTGGAGCAAGAAACAAAAAGGCTTAACAGTATTCTTTCTTATATGACAGATGGAGT
TCTTGCAACCAATCGCCGTGGTCAGATTACTATGATTAACGATATGGCTAAGAAACAGCTGGGTATCGTAAAAGAAGAAG
CATTGAACAAAAGCATCCTGGAATTGCTTAAGATAGAGGATGAATATGAGCTGCGTGACCTCATTACACAGATTCCTGAA
TTGATGATTGATTCCCAAAATGCTAATGGTGAATATCTTAGCCTTCGTGTGCGTTTTGCACTCATTCGTCGTGAGTCTGG
ATTCATCTCTGGTTTGGTTGCCGTTTTGCACGATACGACCGAGCAGGAGAAGGAAGAGCGTGAACGGAGACTCTTCGTGT
CCAATGTTAGCCATGAGTTGCGTACTCCTTTGACCAGTGTTAAATCTTATCTTGAAGCCTTAGACGAGGGAGCCTTGTAT
GATCCTGTTGCCCCTGATTTTATCAAGGTTTCACTCGATGAAACCAACCGTATGATGCGGATGGTGACAGATCTCTTGCA
TCTCTCTCGTATTGATAATGCGACCACTCAGTTGGATGTGGAATTGATTAATTTTACAGCCTTCATCACCTTTATCCTCA
ATCGTTTCGATAAGATGAGGAGCCAGGATGAAGAGAAAAAATATGAGCTGGTTAGAGATTACCCAATCAATTCAGTTTGG
ATCGAGATTGATACTGATAAGATGACCCAGGTGATTGATAATATTCTCAACAATGCTATCAAGTACTCACCAGATGGTGG
GAAAATTACTGTCAGCATGAAAACCACTGAAGACCAGATGATTTTATCTATCAAAGACCAAGGTCTAGGCATTCCAAAGC
AAGATTTGCCGAAGATTTTTGACCGCTTCTACCGTGTGGATCGTGCAAGAAGCCGTGCCCAAGGTGGAACTGGTCTAGGT
CTGGCTATTGCAAAAGAAATCATTAAACAACACAATGGCTTTATTTGGGCCAAAAGTGAATACGGTAAGGGATCAACCTT
TACCATCGTGCTCCCTTATGATAAGGATGCCGTAAAAGAAGAAATATGGGAGGACGAAATAGAAGACTAG

Domains

Predicted by InterproScan.

• PAS fold (PAS) (95-198)

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (324-434)

• His Kinase A (phospho-acceptor) domain (HisKA) (209-273)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
micB	Streptococcus pneumoniae Cp1015	89.749	97.773	0.878
vicK	Streptococcus mutans UA159	70.647	89.532	0.633