Detailed information NTG0403713

Bioinformatically predicted

Overview

• Name: comGE/cglE
• Type: Machinery gene
• Locus tag: GL187_RS09895
• Genome accession: NZ_CP046379
• Coordinates: 1931041..1931343 (-)
• Length: 100 a.a.
• NCBI ID: WP_000413382.1
• Uniprot ID: -
• Organism: Streptococcus pneumoniae strain 563
• Function: dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 1926041..1936343

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
GL187_RS09865 (GL187_09985)	rnpA	1926728..1927099 (-)	372	WP_000739247.1	ribonuclease P protein component	-
GL187_RS11460	-	1927116..1927247 (-)	132	WP_000768904.1	hypothetical protein	-
GL187_RS09870 (GL187_09990)	-	1927248..1928438 (-)	1191	WP_000167765.1	acetate kinase	-
GL187_RS09875 (GL187_09995)	comYH	1928489..1929442 (-)	954	WP_000345122.1	class I SAM-dependent methyltransferase	Machinery gene
GL187_RS09880 (GL187_10005)	-	1929503..1930090 (-)	588	WP_000679779.1	class I SAM-dependent methyltransferase	-
GL187_RS09885 (GL187_10010)	comGG/cglG	1930193..1930639 (-)	447	WP_001811371.1	competence type IV pilus minor pilin ComGG	Machinery gene
GL187_RS09890 (GL187_10015)	comGF/cglF	1930617..1931078 (-)	462	WP_000250523.1	competence type IV pilus minor pilin ComGF	Machinery gene
GL187_RS09895 (GL187_10020)	comGE/cglE	1931041..1931343 (-)	303	WP_000413382.1	competence type IV pilus minor pilin ComGE	Machinery gene
GL187_RS09900 (GL187_10025)	comGD/cglD	1931306..1931710 (-)	405	WP_061647912.1	competence type IV pilus minor pilin ComGD	Machinery gene
GL187_RS09905 (GL187_10030)	comGC/cglC	1931703..1932029 (-)	327	WP_000738625.1	competence type IV pilus major pilin ComGC	Machinery gene
GL187_RS09910 (GL187_10035)	comGB/cglB	1932031..1933047 (-)	1017	WP_074017570.1	competence type IV pilus assembly protein ComGB	Machinery gene
GL187_RS09915 (GL187_10040)	comGA/cglA/cilD	1932995..1933936 (-)	942	WP_000249555.1	competence type IV pilus ATPase ComGA	Machinery gene
GL187_RS09920 (GL187_10045)	-	1934011..1934376 (-)	366	WP_000286415.1	DUF1033 family protein	-
GL187_RS09925 (GL187_10050)	-	1934527..1935585 (-)	1059	WP_000649471.1	zinc-dependent alcohol dehydrogenase family protein	-

Sequence

Protein

• Length: 100 a.a.
• Molecular weight: 11108.08 Da
• Isoelectric Point: 9.7273

>NTDB_id=403713 GL187_RS09895 WP_000413382.1 1931041..1931343(-) (comGE/cglE) [Streptococcus pneumoniae strain 563]
MEKLNALRKQKIRAVILLEAVVALAIFASIATLLLGQIQKNRQEEAKILQKEEVLRVAKMALQTGQNQVSINGVEIQVFS
SEKGLEVYHGSEQLLAIKEP

Nucleotide

• Length: 303 bp

>NTDB_id=403713 GL187_RS09895 WP_000413382.1 1931041..1931343(-) (comGE/cglE) [Streptococcus pneumoniae strain 563]
ATGGAAAAATTAAACGCATTAAGGAAACAAAAAATTAGGGCAGTGATTTTACTGGAAGCAGTAGTCGCTCTAGCTATCTT
TGCCAGCATTGCGACCCTCCTTTTGGGACAAATTCAAAAAAATAGGCAAGAGGAAGCAAAAATCTTGCAAAAGGAAGAAG
TCTTGAGGGTAGCTAAGATGGCCTTGCAGACGGGGCAAAATCAGGTAAGCATCAACGGAGTTGAGATTCAGGTATTTTCT
AGTGAAAAGGGATTGGAGGTCTACCATGGTTCAGAACAGTTGTTGGCAATCAAAGAGCCATAA

Domains

Predicted by InterproScan.

• Type II secretory pathway pseudopilin (ComGE) (16-97)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comGE/cglE	Streptococcus pneumoniae Rx1	100	100	1
comGE/cglE	Streptococcus pneumoniae D39	100	100	1
comGE/cglE	Streptococcus pneumoniae R6	100	100	1
comGE/cglE	Streptococcus pneumoniae TIGR4	100	100	1
comGE/cglE	Streptococcus mitis NCTC 12261	98	100	0.98
comGE/cglE	Streptococcus mitis SK321	98	100	0.98
comYE	Streptococcus mutans UA140	44.444	90	0.4
comYE	Streptococcus mutans UA159	44.444	90	0.4