Detailed information    

insolico Bioinformatically predicted

Overview

Name   comYH   Type   Machinery gene
Locus tag   GL187_RS09875 Genome accession   NZ_CP046379
Coordinates   1928489..1929442 (-) Length   317 a.a.
NCBI ID   WP_000345122.1    Uniprot ID   A0A0I7TJC1
Organism   Streptococcus pneumoniae strain 563     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1923489..1934442
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  GL187_RS09850 (GL187_09970) - 1924250..1924873 (-) 624 WP_000932659.1 hypothetical protein -
  GL187_RS09855 (GL187_09975) jag 1924924..1925910 (-) 987 WP_000260025.1 RNA-binding cell elongation regulator Jag/EloR -
  GL187_RS09860 (GL187_09980) - 1925929..1926753 (-) 825 WP_000727904.1 membrane protein insertase YidC -
  GL187_RS09865 (GL187_09985) rnpA 1926728..1927099 (-) 372 WP_000739247.1 ribonuclease P protein component -
  GL187_RS11460 - 1927116..1927247 (-) 132 WP_000768904.1 hypothetical protein -
  GL187_RS09870 (GL187_09990) - 1927248..1928438 (-) 1191 WP_000167765.1 acetate kinase -
  GL187_RS09875 (GL187_09995) comYH 1928489..1929442 (-) 954 WP_000345122.1 class I SAM-dependent methyltransferase Machinery gene
  GL187_RS09880 (GL187_10005) - 1929503..1930090 (-) 588 WP_000679779.1 class I SAM-dependent methyltransferase -
  GL187_RS09885 (GL187_10010) comGG/cglG 1930193..1930639 (-) 447 WP_001811371.1 competence type IV pilus minor pilin ComGG Machinery gene
  GL187_RS09890 (GL187_10015) comGF/cglF 1930617..1931078 (-) 462 WP_000250523.1 competence type IV pilus minor pilin ComGF Machinery gene
  GL187_RS09895 (GL187_10020) comGE/cglE 1931041..1931343 (-) 303 WP_000413382.1 competence type IV pilus minor pilin ComGE Machinery gene
  GL187_RS09900 (GL187_10025) comGD/cglD 1931306..1931710 (-) 405 WP_061647912.1 competence type IV pilus minor pilin ComGD Machinery gene
  GL187_RS09905 (GL187_10030) comGC/cglC 1931703..1932029 (-) 327 WP_000738625.1 competence type IV pilus major pilin ComGC Machinery gene
  GL187_RS09910 (GL187_10035) comGB/cglB 1932031..1933047 (-) 1017 WP_074017570.1 competence type IV pilus assembly protein ComGB Machinery gene
  GL187_RS09915 (GL187_10040) comGA/cglA/cilD 1932995..1933936 (-) 942 WP_000249555.1 competence type IV pilus ATPase ComGA Machinery gene
  GL187_RS09920 (GL187_10045) - 1934011..1934376 (-) 366 WP_000286415.1 DUF1033 family protein -

Sequence

Protein


Download         Length: 317 a.a.        Molecular weight: 35745.94 Da        Isoelectric Point: 4.2706

>NTDB_id=403710 GL187_RS09875 WP_000345122.1 1928489..1929442(-) (comYH) [Streptococcus pneumoniae strain 563]
MDFEKIEQAYTYLLENVQVIQSDLATNFYDALVEQNSIYLDGETELNQVKDNNQALKRLALRKEEWLKTYQFLLMKAGQT
EPLQANHQFTPDAIALLLVFIVEELFKEEEITILEMGSGMGILGATFLTSLDKKVDYLGMEMDDLLIDLAASMADVIGLQ
AGFVQGDAVRPQMLKESDVVISDLPVGYYPDDAVASRHQVASSQEHTYAHHLLMEQGLKYLKSDGYAIFLAPSNLLTSPQ
SDLLKEWLKEEASLVAMISLPENLFANAKQSKTIFILQKKNEIAVEPFVYPLASLQDASVLMKFKENFQKWTQGTEI

Nucleotide


Download         Length: 954 bp        

>NTDB_id=403710 GL187_RS09875 WP_000345122.1 1928489..1929442(-) (comYH) [Streptococcus pneumoniae strain 563]
ATGGATTTTGAAAAAATTGAACAAGCTTATACCTATTTACTAGAGAATGTCCAAGTTATCCAAAGTGATTTGGCGACCAA
CTTTTATGACGCCTTGGTGGAGCAAAACAGCATCTATCTGGATGGTGAAACTGAGCTAAACCAGGTCAAAGACAACAATC
AGGCCCTTAAGCGTTTAGCACTACGCAAAGAAGAATGGCTCAAGACCTACCAGTTTCTCTTGATGAAGGCTGGGCAAACA
GAACCCTTGCAGGCCAATCACCAGTTTACACCAGATGCCATTGCTTTGCTTTTGGTGTTTATTGTGGAAGAGTTGTTTAA
AGAGGAGGAAATTACTATCCTCGAAATGGGTTCTGGGATGGGAATTCTAGGCGCTACTTTCTTGACCTCGCTTGATAAAA
AGGTGGATTACTTGGGAATGGAAATGGATGATTTGCTGATTGATCTGGCAGCTAGCATGGCAGATGTAATTGGTTTGCAG
GCTGGCTTTGTCCAAGGAGATGCCGTTCGTCCACAAATGCTCAAAGAAAGCGATGTGGTCATCAGTGACTTGCCTGTTGG
CTATTATCCTGATGATGCCGTTGCGTCGCGCCATCAAGTTGCTTCTAGCCAAGAACATACTTACGCCCATCACTTGCTCA
TGGAACAAGGGCTTAAGTACCTCAAGTCAGACGGATACGCTATTTTTCTAGCTCCGAGTAATTTGTTGACCAGTCCTCAA
AGTGATTTGTTAAAAGAATGGCTGAAAGAAGAGGCGAGTCTGGTTGCTATGATTAGTCTGCCTGAAAATCTCTTTGCTAA
TGCCAAACAATCTAAGACTATTTTTATCTTACAGAAGAAAAATGAAATAGCAGTAGAGCCTTTTGTTTATCCACTTGCTA
GCTTGCAAGATGCAAGTGTTTTAATGAAATTTAAAGAAAATTTTCAAAAATGGACTCAAGGTACTGAAATATAA

Domains

Predicted by InterproScan.

N-6 DNA Methylase (N6_Mtase)

(69-282)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A0I7TJC1

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comYH Streptococcus mutans UA140

53.994

98.738

0.533
  comYH Streptococcus mutans UA159

53.674

98.738

0.53

Multiple sequence alignment