Detailed information
Bioinformatically predicted
Overview
| Name | clpP | Type | Regulator |
| Locus tag | GL185_RS04160 | Genome accession | NZ_CP046357 |
| Coordinates | 825887..826477 (-) | Length | 196 a.a. |
| NCBI ID | WP_000613477.1 | Uniprot ID | A0A064BX72 |
| Organism | Streptococcus pneumoniae strain 525 | ||
| Function | degradation of ComX; degradation of ComW (predicted from homology) Competence regulation |
||
Related MGE
Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.
Gene-MGE association summary
| MGE type | MGE coordinates | Gene coordinates | Relative position | Distance (bp) |
|---|---|---|---|---|
| Prophage | 815691..827836 | 825887..826477 | within | 0 |
Gene organization within MGE regions
Location: 815691..827836
| Locus tag | Gene name | Coordinates (strand) | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| GL185_RS04105 (GL185_04150) | - | 815691..816644 (+) | 954 | WP_001155339.1 | IS30-like element ISSpn8 family transposase | - |
| GL185_RS04110 (GL185_04155) | ftsX | 816826..817752 (-) | 927 | WP_024477896.1 | permease-like cell division protein FtsX | - |
| GL185_RS04115 (GL185_04160) | ftsE | 817745..818437 (-) | 693 | WP_000022264.1 | cell division ATP-binding protein FtsE | - |
| GL185_RS04125 (GL185_04170) | - | 819658..820314 (-) | 657 | WP_000268677.1 | CBS domain-containing protein | - |
| GL185_RS04130 (GL185_04175) | - | 820728..821438 (-) | 711 | WP_000062219.1 | ABC transporter ATP-binding protein | - |
| GL185_RS04135 (GL185_04180) | - | 821438..822202 (-) | 765 | WP_001186003.1 | ABC transporter ATP-binding protein | - |
| GL185_RS04140 (GL185_04185) | - | 822202..823158 (-) | 957 | WP_000662292.1 | branched-chain amino acid ABC transporter permease | - |
| GL185_RS04145 (GL185_04190) | - | 823162..824031 (-) | 870 | WP_000941421.1 | branched-chain amino acid ABC transporter permease | - |
| GL185_RS04150 (GL185_04195) | - | 824299..825459 (-) | 1161 | WP_000726146.1 | ABC transporter substrate-binding protein | - |
| GL185_RS04155 (GL185_04200) | - | 825560..825808 (-) | 249 | WP_000462126.1 | YlbG family protein | - |
| GL185_RS04160 (GL185_04205) | clpP | 825887..826477 (-) | 591 | WP_000613477.1 | ATP-dependent Clp protease proteolytic subunit ClpP | Regulator |
| GL185_RS04165 (GL185_04210) | upp | 826651..827280 (-) | 630 | WP_001812010.1 | uracil phosphoribosyltransferase | - |
| GL185_RS04170 (GL185_04215) | - | 827369..827836 (-) | 468 | WP_000136976.1 | cytidine/deoxycytidylate deaminase family protein | - |
Sequence
Protein
Download Length: 196 a.a. Molecular weight: 21358.36 Da Isoelectric Point: 4.4910
>NTDB_id=403165 GL185_RS04160 WP_000613477.1 825887..826477(-) (clpP) [Streptococcus pneumoniae strain 525]
MIPVVIEQTSRGERSYDIYSRLLKDRIIMLTGPVEDNMANSVIAQLLFLDAQDSTKDIYLYVNTPGGSVSAGLAIVDTMN
FIKADVQTIVMGMAASMGTVIASSGAKGKRFMLPNAEYMIHQPMGGTGGGTQQTDMAIAAEHLLKTRNTLEKILAENSGQ
SMEKVHADAERDNWMSAQETLEYGFIDEIMANNSLN
MIPVVIEQTSRGERSYDIYSRLLKDRIIMLTGPVEDNMANSVIAQLLFLDAQDSTKDIYLYVNTPGGSVSAGLAIVDTMN
FIKADVQTIVMGMAASMGTVIASSGAKGKRFMLPNAEYMIHQPMGGTGGGTQQTDMAIAAEHLLKTRNTLEKILAENSGQ
SMEKVHADAERDNWMSAQETLEYGFIDEIMANNSLN
Nucleotide
Download Length: 591 bp
>NTDB_id=403165 GL185_RS04160 WP_000613477.1 825887..826477(-) (clpP) [Streptococcus pneumoniae strain 525]
ATGATTCCTGTAGTTATTGAACAAACAAGCCGTGGAGAACGTTCTTACGATATTTACTCACGTCTTCTCAAAGACCGCAT
CATTATGCTGACAGGTCCGGTTGAAGACAATATGGCTAACTCTGTTATTGCCCAATTGCTTTTCTTGGATGCCCAAGATA
GTACAAAAGATATTTACCTTTATGTCAATACACCAGGTGGTTCTGTTTCAGCTGGTTTGGCAATCGTAGATACCATGAAC
TTTATCAAGGCAGATGTCCAAACCATTGTTATGGGAATGGCTGCATCTATGGGAACAGTCATCGCATCAAGTGGAGCAAA
AGGCAAACGTTTCATGCTTCCAAATGCTGAATACATGATTCACCAACCAATGGGCGGTACAGGTGGTGGTACCCAACAAA
CTGATATGGCTATCGCTGCAGAACACTTGCTCAAAACTCGTAATACCTTGGAAAAAATCTTGGCTGAAAATTCAGGTCAG
TCAATGGAAAAAGTCCATGCAGATGCAGAACGTGATAACTGGATGAGCGCCCAGGAAACACTTGAATATGGCTTTATTGA
TGAAATTATGGCCAACAATTCATTGAACTAA
ATGATTCCTGTAGTTATTGAACAAACAAGCCGTGGAGAACGTTCTTACGATATTTACTCACGTCTTCTCAAAGACCGCAT
CATTATGCTGACAGGTCCGGTTGAAGACAATATGGCTAACTCTGTTATTGCCCAATTGCTTTTCTTGGATGCCCAAGATA
GTACAAAAGATATTTACCTTTATGTCAATACACCAGGTGGTTCTGTTTCAGCTGGTTTGGCAATCGTAGATACCATGAAC
TTTATCAAGGCAGATGTCCAAACCATTGTTATGGGAATGGCTGCATCTATGGGAACAGTCATCGCATCAAGTGGAGCAAA
AGGCAAACGTTTCATGCTTCCAAATGCTGAATACATGATTCACCAACCAATGGGCGGTACAGGTGGTGGTACCCAACAAA
CTGATATGGCTATCGCTGCAGAACACTTGCTCAAAACTCGTAATACCTTGGAAAAAATCTTGGCTGAAAATTCAGGTCAG
TCAATGGAAAAAGTCCATGCAGATGCAGAACGTGATAACTGGATGAGCGCCCAGGAAACACTTGAATATGGCTTTATTGA
TGAAATTATGGCCAACAATTCATTGAACTAA
Similar proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|---|---|---|---|
| clpP | Streptococcus pneumoniae Rx1 |
100 |
100 |
1 |
| clpP | Streptococcus pneumoniae D39 |
100 |
100 |
1 |
| clpP | Streptococcus pneumoniae R6 |
100 |
100 |
1 |
| clpP | Streptococcus pneumoniae TIGR4 |
100 |
100 |
1 |
| clpP | Streptococcus thermophilus LMG 18311 |
92.821 |
99.49 |
0.923 |
| clpP | Streptococcus thermophilus LMD-9 |
92.821 |
99.49 |
0.923 |
| clpP | Streptococcus pyogenes JRS4 |
90.769 |
99.49 |
0.903 |
| clpP | Streptococcus pyogenes MGAS315 |
90.769 |
99.49 |
0.903 |
| clpP | Streptococcus mutans UA159 |
85.714 |
100 |
0.857 |
| clpP | Lactococcus lactis subsp. lactis strain DGCC12653 |
85.128 |
99.49 |
0.847 |
| clpP | Lactococcus lactis subsp. cremoris KW2 |
84.615 |
99.49 |
0.842 |
| clpP | Bacillus subtilis subsp. subtilis str. 168 |
58.854 |
97.959 |
0.577 |
| clpP | Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819 |
58.031 |
98.469 |
0.571 |