Detailed information    

insolico Bioinformatically predicted

Overview

Name   comA/nlmT   Type   Regulator
Locus tag   GL184_RS08470 Genome accession   NZ_CP046356
Coordinates   1654184..1655827 (+) Length   547 a.a.
NCBI ID   WP_078133412.1    Uniprot ID   -
Organism   Streptococcus pneumoniae strain 521     
Function   transport of ComC (predicted from homology)   
Competence regulation

Genomic Context

Location: 1649184..1660827
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  GL184_RS08430 (GL184_08505) - 1649671..1650054 (-) 384 WP_000877381.1 hypothetical protein -
  GL184_RS08435 (GL184_08510) - 1650683..1651041 (-) 359 Protein_1634 immunity protein -
  GL184_RS08440 (GL184_08520) - 1651522..1651641 (-) 120 WP_000346296.1 PncF family bacteriocin immunity protein -
  GL184_RS11660 - 1651644..1651709 (-) 66 Protein_1636 ComC/BlpC family peptide pheromone/bacteriocin -
  GL184_RS08445 (GL184_08525) cipB 1651745..1651894 (-) 150 WP_001809846.1 bacteriocin-like peptide BlpO Regulator
  GL184_RS08450 (GL184_08530) blpK 1652138..1652386 (-) 249 WP_000379965.1 bacteriocin-like peptide BlpK -
  GL184_RS08455 (GL184_08535) blpJ 1652455..1652724 (-) 270 WP_001093248.1 bacteriocin-like peptide BlpJ -
  GL184_RS08460 (GL184_08540) blpI 1653191..1653388 (-) 198 WP_001093259.1 bacteriocin-like peptide BlpI -
  GL184_RS11615 comA/nlmT 1653670..1654257 (+) 588 WP_000205166.1 cysteine peptidase family C39 domain-containing protein Regulator
  GL184_RS08470 (GL184_08545) comA/nlmT 1654184..1655827 (+) 1644 WP_078133412.1 peptide cleavage/export ABC transporter Regulator
  GL184_RS08475 (GL184_08550) - 1655838..1657199 (+) 1362 WP_001069060.1 bacteriocin secretion accessory protein -
  GL184_RS08480 (GL184_08555) blpC 1657256..1657384 (+) 129 WP_000358815.1 quorum-sensing system pheromone BlpC -
  GL184_RS08485 (GL184_08560) - 1657566..1657895 (+) 330 WP_000132572.1 hypothetical protein -
  GL184_RS08490 (GL184_08565) - 1658063..1659112 (-) 1050 WP_000653771.1 ABC transporter permease -
  GL184_RS08495 (GL184_08570) pptA 1659109..1659840 (-) 732 WP_000889921.1 ABC transporter ATP-binding protein Regulator
  GL184_RS08500 (GL184_08575) - 1659908..1660318 (+) 411 WP_001278301.1 HIT family protein -
  GL184_RS08505 (GL184_08580) - 1660328..1660615 (+) 288 WP_000777753.1 hypothetical protein -

Sequence

Protein


Download         Length: 547 a.a.        Molecular weight: 61671.67 Da        Isoelectric Point: 6.5088

>NTDB_id=403135 GL184_RS08470 WP_078133412.1 1654184..1655827(+) (comA/nlmT) [Streptococcus pneumoniae strain 521]
MVLSSLLVTIINIGGSYYLQGILDEYIPNQMKSTLGIISVGLVITYILQQVMSFSRDYLLTVLSQRLSIDVILSYIRHIF
ELPMSFFATRRTGEIISRFTDANSIIDALASTILSLFLDVSILILVGGVLLVQNPNLFLLSLISIPIYMFIIFSFMKPFE
KMNHDVMQSNSMVSSAIIEDINGIETIKSLTSEENRYQNIDSEFVDYLEKSFKLSKYSILQTSLKQGTKLVLNILILWFG
AQLVMSSKISIGQLITFNTLFSYFTTPMENIINLQTKLQSAKVANNRLNEVYLVESEFQVQENPVHSHFLMGDIEFDDLS
YKYGFGRDTLTDINLTIKQGDKVSLVGVSGSGKTTLAKMIVNFFEPYKGHISINHQDIKNIDKKVLRRHINYLPQQAYIF
NGSILENLTLGGNHMISQEDILRACELAEIRQDIERMPMGYQTQLSDGAGLSGGQKQRIALARALLTKAPVLILDEATSG
LDVLTEKKVIDNLMSLTDKTILFVAHRLSIAERTNRVIVLDQGKIIEVGSHQELMQAQGFYHHLFNK

Nucleotide


Download         Length: 1644 bp        

>NTDB_id=403135 GL184_RS08470 WP_078133412.1 1654184..1655827(+) (comA/nlmT) [Streptococcus pneumoniae strain 521]
ATTGTTCTCTCAAGCTTATTGGTCACTATTATCAATATAGGTGGTTCTTACTATCTCCAAGGAATCTTGGATGAATACAT
TCCAAATCAGATGAAATCAACTTTAGGAATCATCTCAGTTGGTCTGGTTATCACCTATATCCTCCAACAAGTCATGAGCT
TCTCCAGAGATTATCTCCTAACCGTTCTGAGTCAGAGATTAAGTATTGATGTGATTTTATCCTATATTCGCCATATTTTT
GAACTTCCCATGTCTTTCTTTGCGACACGTCGTACAGGAGAAATCATTTCACGATTCACAGATGCTAACTCTATTATAGA
TGCCTTGGCTTCTACCATTCTTTCTCTTTTTCTGGATGTTTCTATTCTGATTCTTGTAGGAGGCGTCTTACTGGTACAAA
ACCCTAATCTCTTCCTTCTTTCTCTTATTTCCATTCCTATATACATGTTCATCATCTTTTCTTTTATGAAACCTTTCGAA
AAAATGAACCATGATGTCATGCAAAGTAATTCTATGGTTAGCTCTGCCATTATCGAAGATATCAACGGGATTGAAACTAT
AAAGTCGCTCACGAGTGAAGAAAATCGCTATCAAAATATAGACAGCGAATTTGTAGATTATTTGGAAAAATCCTTTAAGC
TCAGTAAATATTCTATTTTACAAACGAGTTTAAAGCAGGGAACAAAATTAGTTCTGAATATCCTTATCCTATGGTTTGGC
GCTCAATTAGTCATGTCGAGTAAAATTTCTATCGGTCAGCTGATTACCTTTAACACACTTTTTTCTTACTTTACAACTCC
TATGGAAAATATTATCAACCTCCAAACCAAACTCCAATCTGCGAAGGTCGCTAATAACCGTTTGAACGAAGTCTATCTAG
TCGAATCTGAATTTCAAGTTCAAGAAAACCCTGTCCATTCACATTTTTTGATGGGCGATATTGAATTTGATGACCTTTCT
TATAAGTATGGTTTTGGACGAGATACCTTAACAGATATTAATCTCACGATTAAACAAGGAGATAAGGTTAGCCTAGTTGG
AGTTAGTGGTTCTGGTAAAACAACTTTAGCCAAAATGATTGTCAATTTCTTTGAACCCTACAAAGGACATATTTCTATCA
ATCATCAGGATATTAAAAACATTGATAAAAAAGTCTTGCGCCGTCATATTAATTACCTACCACAACAAGCCTATATCTTT
AATGGCTCTATCTTGGAAAACTTAACTTTGGGCGGTAATCATATGATTAGCCAAGAAGATATTCTAAGAGCTTGTGAATT
AGCTGAAATTCGTCAAGACATTGAAAGAATGCCTATGGGCTATCAAACTCAGCTCTCTGATGGAGCTGGTCTATCAGGAG
GACAAAAGCAACGAATAGCCCTCGCTCGTGCTCTTTTAACTAAAGCTCCTGTTTTAATACTAGACGAAGCTACTAGCGGT
CTTGATGTCTTGACTGAGAAAAAGGTTATAGATAATCTTATGTCTCTAACTGATAAAACCATTCTCTTTGTAGCCCATCG
TCTCAGTATAGCCGAACGAACCAACCGTGTCATTGTTCTTGACCAGGGGAAAATCATTGAAGTTGGTAGTCACCAAGAGT
TAATGCAGGCGCAAGGTTTCTACCATCATCTATTCAATAAATAA

Domains

Predicted by InterProScan.

ABC transporter (ABC_tran)

(330-479)

ABC transporter transmembrane region (ABC_membrane)

(2-268)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comA/nlmT Streptococcus mutans UA159

72.894

99.817

0.728
  comA Streptococcus mitis NCTC 12261

67.824

100

0.678
  comA Streptococcus pneumoniae D39

67.459

100

0.675
  comA Streptococcus pneumoniae R6

67.459

100

0.675
  comA Streptococcus pneumoniae Rx1

67.459

100

0.675
  comA Streptococcus mitis SK321

67.276

100

0.673
  comA Streptococcus gordonii str. Challis substr. CH1

67.153

100

0.673
  comA Streptococcus pneumoniae TIGR4

67.093

100

0.671

Multiple sequence alignment