Detailed information    

insolico Bioinformatically predicted

Overview

Name   comA/nlmT   Type   Regulator
Locus tag   GLO74_RS08435 Genome accession   NZ_CP046354
Coordinates   1646291..1647934 (+) Length   547 a.a.
NCBI ID   WP_078133412.1    Uniprot ID   -
Organism   Streptococcus pneumoniae strain 310     
Function   transport of ComC (predicted from homology)   
Competence regulation

Genomic Context

Location: 1641291..1652934
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  GLO74_RS08395 (GLO74_08515) - 1641778..1642161 (-) 384 WP_000877381.1 hypothetical protein -
  GLO74_RS08400 (GLO74_08520) - 1642790..1643148 (-) 359 Protein_1624 immunity protein -
  GLO74_RS08405 (GLO74_08530) - 1643629..1643748 (-) 120 WP_000346296.1 PncF family bacteriocin immunity protein -
  GLO74_RS11515 - 1643751..1643816 (-) 66 Protein_1626 ComC/BlpC family peptide pheromone/bacteriocin -
  GLO74_RS08410 (GLO74_08535) cipB 1643852..1644001 (-) 150 WP_001809846.1 bacteriocin-like peptide BlpO Regulator
  GLO74_RS08415 (GLO74_08540) blpK 1644245..1644493 (-) 249 WP_000379965.1 bacteriocin-like peptide BlpK -
  GLO74_RS08420 (GLO74_08545) blpJ 1644562..1644831 (-) 270 WP_001093248.1 bacteriocin-like peptide BlpJ -
  GLO74_RS08425 (GLO74_08550) blpI 1645298..1645495 (-) 198 WP_001093259.1 bacteriocin-like peptide BlpI -
  GLO74_RS11480 comA/nlmT 1645777..1646364 (+) 588 WP_000205166.1 cysteine peptidase family C39 domain-containing protein Regulator
  GLO74_RS08435 (GLO74_08555) comA/nlmT 1646291..1647934 (+) 1644 WP_078133412.1 peptide cleavage/export ABC transporter Regulator
  GLO74_RS08440 (GLO74_08560) - 1647945..1649306 (+) 1362 WP_197097175.1 bacteriocin secretion accessory protein -
  GLO74_RS08445 (GLO74_08565) blpC 1649363..1649491 (+) 129 WP_000358815.1 quorum-sensing system pheromone BlpC -
  GLO74_RS08450 (GLO74_08570) - 1649562..1650902 (-) 1341 WP_001017642.1 sensor histidine kinase -
  GLO74_RS08455 (GLO74_08575) comE/blpR 1650916..1651653 (-) 738 WP_001219120.1 response regulator transcription factor Regulator
  GLO74_RS08460 (GLO74_08580) - 1651658..1651996 (-) 339 WP_000876675.1 LytTR family DNA-binding domain-containing protein -
  GLO74_RS08465 (GLO74_08585) - 1652272..1652601 (+) 330 WP_000132572.1 hypothetical protein -

Sequence

Protein


Download         Length: 547 a.a.        Molecular weight: 61671.67 Da        Isoelectric Point: 6.5088

>NTDB_id=402978 GLO74_RS08435 WP_078133412.1 1646291..1647934(+) (comA/nlmT) [Streptococcus pneumoniae strain 310]
MVLSSLLVTIINIGGSYYLQGILDEYIPNQMKSTLGIISVGLVITYILQQVMSFSRDYLLTVLSQRLSIDVILSYIRHIF
ELPMSFFATRRTGEIISRFTDANSIIDALASTILSLFLDVSILILVGGVLLVQNPNLFLLSLISIPIYMFIIFSFMKPFE
KMNHDVMQSNSMVSSAIIEDINGIETIKSLTSEENRYQNIDSEFVDYLEKSFKLSKYSILQTSLKQGTKLVLNILILWFG
AQLVMSSKISIGQLITFNTLFSYFTTPMENIINLQTKLQSAKVANNRLNEVYLVESEFQVQENPVHSHFLMGDIEFDDLS
YKYGFGRDTLTDINLTIKQGDKVSLVGVSGSGKTTLAKMIVNFFEPYKGHISINHQDIKNIDKKVLRRHINYLPQQAYIF
NGSILENLTLGGNHMISQEDILRACELAEIRQDIERMPMGYQTQLSDGAGLSGGQKQRIALARALLTKAPVLILDEATSG
LDVLTEKKVIDNLMSLTDKTILFVAHRLSIAERTNRVIVLDQGKIIEVGSHQELMQAQGFYHHLFNK

Nucleotide


Download         Length: 1644 bp        

>NTDB_id=402978 GLO74_RS08435 WP_078133412.1 1646291..1647934(+) (comA/nlmT) [Streptococcus pneumoniae strain 310]
ATTGTTCTCTCAAGCTTATTGGTCACTATTATCAATATAGGTGGTTCTTACTATCTCCAAGGAATCTTGGATGAATACAT
TCCAAATCAGATGAAATCAACTTTAGGAATCATCTCAGTTGGTCTGGTTATCACCTATATCCTCCAACAAGTCATGAGCT
TCTCCAGAGATTATCTCCTAACCGTTCTGAGTCAGAGATTAAGTATTGATGTGATTTTATCCTATATTCGCCATATTTTT
GAACTTCCCATGTCTTTCTTTGCGACACGTCGTACAGGAGAAATCATTTCACGATTCACAGATGCTAACTCTATTATAGA
TGCCTTGGCTTCTACCATTCTTTCTCTTTTTCTGGATGTTTCTATTCTGATTCTTGTAGGAGGCGTCTTACTGGTACAAA
ACCCTAATCTCTTCCTTCTTTCTCTTATTTCCATTCCTATATACATGTTCATCATCTTTTCTTTTATGAAACCTTTCGAA
AAAATGAACCATGATGTCATGCAAAGTAATTCTATGGTTAGCTCTGCCATTATCGAAGATATCAACGGGATTGAAACTAT
AAAGTCGCTCACGAGTGAAGAAAATCGCTATCAAAATATAGACAGCGAATTTGTAGATTATTTGGAAAAATCCTTTAAGC
TCAGTAAATATTCTATTTTACAAACGAGTTTAAAGCAGGGAACAAAATTAGTTCTGAATATCCTTATCCTATGGTTTGGC
GCTCAATTAGTCATGTCGAGTAAAATTTCTATCGGTCAGCTGATTACCTTTAACACACTTTTTTCTTACTTTACAACTCC
TATGGAAAATATTATCAACCTCCAAACCAAACTCCAATCTGCGAAGGTCGCTAATAACCGTTTGAACGAAGTCTATCTAG
TCGAATCTGAATTTCAAGTTCAAGAAAACCCTGTCCATTCACATTTTTTGATGGGCGATATTGAATTTGATGACCTTTCT
TATAAGTATGGTTTTGGACGAGATACCTTAACAGATATTAATCTCACGATTAAACAAGGAGATAAGGTTAGCCTAGTTGG
AGTTAGTGGTTCTGGTAAAACAACTTTAGCCAAAATGATTGTCAATTTCTTTGAACCCTACAAAGGACATATTTCTATCA
ATCATCAGGATATTAAAAACATTGATAAAAAAGTCTTGCGCCGTCATATTAATTACCTACCACAACAAGCCTATATCTTT
AATGGCTCTATCTTGGAAAACTTAACTTTGGGCGGTAATCATATGATTAGCCAAGAAGATATTCTAAGAGCTTGTGAATT
AGCTGAAATTCGTCAAGACATTGAAAGAATGCCTATGGGCTATCAAACTCAGCTCTCTGATGGAGCTGGTCTATCAGGAG
GACAAAAGCAACGAATAGCCCTCGCTCGTGCTCTTTTAACTAAAGCTCCTGTTTTAATACTAGACGAAGCTACTAGCGGT
CTTGATGTCTTGACTGAGAAAAAGGTTATAGATAATCTTATGTCTCTAACTGATAAAACCATTCTCTTTGTAGCCCATCG
TCTCAGTATAGCCGAACGAACCAACCGTGTCATTGTTCTTGACCAGGGGAAAATCATTGAAGTTGGTAGTCACCAAGAGT
TAATGCAGGCGCAAGGTTTCTACCATCATCTATTCAATAAATAA

Domains

Predicted by InterproScan.

ABC transporter (ABC_tran)

(330-479)

ABC transporter transmembrane region (ABC_membrane)

(2-268)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comA/nlmT Streptococcus mutans UA159

72.894

99.817

0.728
  comA Streptococcus mitis NCTC 12261

67.824

100

0.678
  comA Streptococcus pneumoniae D39

67.459

100

0.675
  comA Streptococcus pneumoniae R6

67.459

100

0.675
  comA Streptococcus pneumoniae Rx1

67.459

100

0.675
  comA Streptococcus mitis SK321

67.276

100

0.673
  comA Streptococcus gordonii str. Challis substr. CH1

67.153

100

0.673
  comA Streptococcus pneumoniae TIGR4

67.093

100

0.671

Multiple sequence alignment