Detailed information NTG0402720

Bioinformatically predicted

Overview

• Name: cclA/cilC
• Type: Machinery gene
• Locus tag: FOB91_RS10050
• Genome accession: NZ_CP046328
• Coordinates: 2078333..2078995 (-)
• Length: 220 a.a.
• NCBI ID: WP_012000141.1
• Uniprot ID: A8AW07
• Organism: Streptococcus gordonii strain FDAARGOS_683
• Function: processing and translocation of ComGC; assembly of the pseudopilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 2073333..2083995

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
FOB91_RS10020 (FOB91_10020)	-	2073463..2074026 (+)	564	WP_012000135.1	aminodeoxychorismate/anthranilate synthase component II	-
FOB91_RS10025 (FOB91_10025)	trpD	2074037..2075041 (+)	1005	WP_012000136.1	anthranilate phosphoribosyltransferase	-
FOB91_RS10030 (FOB91_10030)	trpC	2075038..2075805 (+)	768	WP_012000137.1	indole-3-glycerol phosphate synthase TrpC	-
FOB91_RS10035 (FOB91_10035)	-	2075792..2076379 (+)	588	WP_012000138.1	phosphoribosylanthranilate isomerase	-
FOB91_RS10040 (FOB91_10040)	trpB	2076369..2077592 (+)	1224	WP_012000139.1	tryptophan synthase subunit beta	-
FOB91_RS10045 (FOB91_10045)	trpA	2077585..2078364 (+)	780	WP_012000140.1	tryptophan synthase subunit alpha	-
FOB91_RS10050 (FOB91_10050)	cclA/cilC	2078333..2078995 (-)	663	WP_012000141.1	prepilin peptidase	Machinery gene
FOB91_RS10060 (FOB91_10060)	-	2079164..2079679 (+)	516	WP_008809115.1	Dps family protein	-
FOB91_RS10065 (FOB91_10065)	-	2079857..2080081 (+)	225	WP_041789586.1	YqgQ family protein	-
FOB91_RS10070 (FOB91_10070)	-	2080069..2080455 (+)	387	WP_008809113.1	rhodanese-like domain-containing protein	-
FOB91_RS10075 (FOB91_10075)	-	2080621..2081346 (-)	726	WP_012000143.1	16S rRNA pseudouridine(516) synthase	-
FOB91_RS10080 (FOB91_10080)	typA	2081528..2083375 (+)	1848	WP_012000144.1	translational GTPase TypA	-
FOB91_RS10085 (FOB91_10085)	-	2083399..2083677 (+)	279	WP_012000145.1	DUF3165 family protein	-

Sequence

Protein

• Length: 220 a.a.
• Molecular weight: 24731.17 Da
• Isoelectric Point: 8.6451

>NTDB_id=402720 FOB91_RS10050 WP_012000141.1 2078333..2078995(-) (cclA/cilC) [Streptococcus gordonii strain FDAARGOS_683]
MIHLYFFLVGTVFASFLGLVIDRFPEQSIITPASHCNACGKRLAPRDLIPIVSQVLNRLRCRFCGDKIPLRYLFFECIFG
CLFLATSLGTISISQLLLLTMGITLAIYDQRELQYPLMIWLVFQLLLLMISGINLLILFFLALGLLAFFYNLRIGAGDFL
FLASCSAIFSLTEILILIQIASFSGLACFCFKKKKDRLAFVPCLLFGVVVIISYKLLLLG

Nucleotide

• Length: 663 bp

>NTDB_id=402720 FOB91_RS10050 WP_012000141.1 2078333..2078995(-) (cclA/cilC) [Streptococcus gordonii strain FDAARGOS_683]
ATGATTCACCTATACTTTTTTCTTGTTGGTACCGTCTTTGCCTCATTCCTAGGCTTGGTCATCGACCGCTTCCCAGAGCA
GTCTATCATCACACCAGCTAGTCATTGTAATGCCTGTGGGAAAAGACTGGCCCCTCGTGACTTGATTCCTATTGTTTCCC
AAGTCTTGAACCGTCTTCGCTGTCGCTTCTGTGGAGACAAGATTCCCTTACGTTATTTATTTTTTGAATGTATCTTTGGC
TGTCTTTTTCTGGCCACTTCACTTGGTACAATTTCTATCAGTCAACTCCTGCTACTTACCATGGGCATAACGTTGGCCAT
ATATGATCAAAGAGAGCTGCAATACCCCTTAATGATCTGGTTAGTTTTTCAGCTCTTGTTGCTAATGATATCGGGCATCA
ATCTTCTCATACTCTTCTTTTTAGCCCTAGGACTTCTAGCCTTCTTTTATAATCTTCGTATTGGAGCTGGTGACTTTCTT
TTTCTTGCTTCCTGCTCAGCCATTTTTAGTCTGACGGAAATTCTCATTCTTATCCAAATCGCTAGCTTCTCTGGCCTCGC
CTGTTTCTGCTTTAAAAAGAAAAAAGACAGGCTGGCATTTGTACCCTGTCTTTTGTTTGGTGTGGTGGTGATTATTTCTT
ATAAGCTGCTGCTTCTTGGATAA

Domains

Predicted by InterproScan.

• Bacterial Peptidase A24 N-terminal domain (A24_N_bact) (8-86)

3D structure

• AlphaFold DB: A8AW07

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
cclA/cilC	Streptococcus mitis NCTC 12261	59.361	99.545	0.591
cclA/cilC	Streptococcus mitis SK321	58.904	99.545	0.586
cclA/cilC	Streptococcus pneumoniae Rx1	57.991	99.545	0.577
cclA/cilC	Streptococcus pneumoniae D39	57.991	99.545	0.577
cclA/cilC	Streptococcus pneumoniae R6	57.991	99.545	0.577
cclA/cilC	Streptococcus pneumoniae TIGR4	57.534	99.545	0.573