Detailed information    

insolico Bioinformatically predicted

Overview

Name   ciaR   Type   Regulator
Locus tag   FOB91_RS01415 Genome accession   NZ_CP046328
Coordinates   289135..289809 (+) Length   224 a.a.
NCBI ID   WP_048774883.1    Uniprot ID   -
Organism   Streptococcus gordonii strain FDAARGOS_683     
Function   repress competence development; post-transcriptional repression of CSP production (predicted from homology)   
Competence regulation

Genomic Context

Location: 284135..294809
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  FOB91_RS01390 (FOB91_01390) - 284433..284729 (+) 297 WP_012000479.1 hypothetical protein -
  FOB91_RS01395 (FOB91_01395) - 284738..285064 (+) 327 WP_012000480.1 hypothetical protein -
  FOB91_RS01400 (FOB91_01400) - 285195..287738 (+) 2544 WP_012000481.1 M1 family metallopeptidase -
  FOB91_RS01405 (FOB91_01405) - 287795..288337 (-) 543 WP_012000482.1 biotin transporter BioY -
  FOB91_RS01410 (FOB91_01410) - 288549..289004 (+) 456 WP_012000483.1 hypothetical protein -
  FOB91_RS01415 (FOB91_01415) ciaR 289135..289809 (+) 675 WP_048774883.1 response regulator transcription factor Regulator
  FOB91_RS01420 (FOB91_01420) ciaH 289799..291199 (+) 1401 WP_012000485.1 sensor histidine kinase Regulator
  FOB91_RS01425 (FOB91_01425) - 291201..292127 (+) 927 WP_012000486.1 ketopantoate reductase family protein -
  FOB91_RS01430 (FOB91_01430) - 292151..293602 (-) 1452 WP_012000487.1 alpha-amylase -
  FOB91_RS01435 (FOB91_01435) rpsT 293829..294077 (-) 249 WP_008808726.1 30S ribosomal protein S20 -

Sequence

Protein


Download         Length: 224 a.a.        Molecular weight: 25375.07 Da        Isoelectric Point: 4.3228

>NTDB_id=402657 FOB91_RS01415 WP_048774883.1 289135..289809(+) (ciaR) [Streptococcus gordonii strain FDAARGOS_683]
MIKILLVEDDLGLSNSVFDFLDDFADVMQVFDGEEGLYEAESGVYDLILLDLMLPEKDGFQVLKDLREKGVSTPVLIMTA
KESLDDKGHGFELGADDYLTKPFYLEELKMRIQALLKRSGKFNENNLSYGDVTVNLSTNTTLVNGKEVELLGKEFDLLVY
FLQNQNVILPKTQIFDRLWGFDSDTTISVVEVYVSKIRKKLKGTTFANNMQTLRSVGYILKNAE

Nucleotide


Download         Length: 675 bp        

>NTDB_id=402657 FOB91_RS01415 WP_048774883.1 289135..289809(+) (ciaR) [Streptococcus gordonii strain FDAARGOS_683]
ATGATTAAGATTTTACTAGTAGAAGACGACTTAGGGTTGTCAAACTCTGTATTTGATTTCTTAGATGACTTTGCGGATGT
CATGCAGGTTTTTGATGGTGAAGAAGGTCTCTATGAAGCTGAAAGCGGTGTTTATGATCTGATTCTACTGGATCTGATGC
TTCCTGAAAAAGATGGCTTTCAAGTTTTGAAAGACTTGCGTGAAAAAGGAGTCTCAACTCCTGTTCTCATCATGACTGCT
AAAGAAAGTTTGGATGATAAAGGACATGGCTTTGAATTAGGAGCAGATGACTATCTAACCAAGCCGTTTTATTTAGAAGA
ATTAAAGATGCGGATCCAGGCCTTACTCAAGCGTTCAGGAAAATTTAATGAAAATAATTTATCATATGGTGATGTGACAG
TAAATCTTTCTACCAATACCACTTTGGTGAATGGAAAAGAAGTAGAATTACTGGGAAAAGAATTTGATTTATTAGTTTAT
TTCCTGCAGAACCAAAACGTAATTCTACCTAAAACTCAGATTTTTGATCGGCTTTGGGGCTTTGACAGTGATACTACCAT
TTCTGTCGTTGAAGTCTATGTCTCAAAAATTCGGAAAAAATTGAAAGGAACGACTTTTGCGAATAATATGCAAACCCTTC
GCAGTGTCGGTTACATTTTGAAGAATGCTGAATAA

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(4-112)

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(145-220)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  ciaR Streptococcus pneumoniae TIGR4

90.179

100

0.902
  ciaR Streptococcus pneumoniae Rx1

90.179

100

0.902
  ciaR Streptococcus pneumoniae D39

90.179

100

0.902
  ciaR Streptococcus pneumoniae R6

90.179

100

0.902
  ciaR Streptococcus mutans UA159

90.135

99.554

0.897
  covR Lactococcus lactis subsp. lactis strain DGCC12653

39.556

100

0.397
  vicR Streptococcus mutans UA159

35.47

100

0.371
  covR Streptococcus salivarius strain HSISS4

36.283

100

0.366
  micA Streptococcus pneumoniae Cp1015

34.764

100

0.362

Multiple sequence alignment