Detailed information    

insolico Bioinformatically predicted

Overview

Name   comEA/celA/cilE   Type   Machinery gene
Locus tag   SOR_RS05930 Genome accession   NC_015291
Coordinates   1190960..1191610 (-) Length   216 a.a.
NCBI ID   WP_000387358.1    Uniprot ID   F2QE03
Organism   Streptococcus oralis Uo5     
Function   dsDNA binding to the cell surface (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1185960..1196610
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SOR_RS05910 (SOR_1210) rplT 1187342..1187701 (-) 360 WP_000124830.1 50S ribosomal protein L20 -
  SOR_RS05915 (SOR_1211) rpmI 1187753..1187953 (-) 201 WP_001125942.1 50S ribosomal protein L35 -
  SOR_RS05920 (SOR_1212) infC 1187986..1188516 (-) 531 WP_000848184.1 translation initiation factor IF-3 -
  SOR_RS05925 (SOR_1213) comEC/celB 1188736..1190976 (-) 2241 WP_000942376.1 DNA internalization-related competence protein ComEC/Rec2 Machinery gene
  SOR_RS05930 (SOR_1214) comEA/celA/cilE 1190960..1191610 (-) 651 WP_000387358.1 helix-hairpin-helix domain-containing protein Machinery gene
  SOR_RS05935 (SOR_1215) - 1191677..1192246 (-) 570 WP_000443901.1 GNAT family N-acetyltransferase -
  SOR_RS05940 (SOR_1216) ald 1192423..1193541 (+) 1119 WP_000904695.1 alanine dehydrogenase -
  SOR_RS05945 (SOR_1217) - 1193586..1194572 (-) 987 WP_000658194.1 PhoH family protein -
  SOR_RS05950 (SOR_1218) - 1194653..1194868 (-) 216 WP_001232089.1 YozE family protein -
  SOR_RS05955 (SOR_1219) cvfB 1194877..1195731 (-) 855 WP_001095427.1 RNA-binding virulence regulatory protein CvfB -
  SOR_RS05960 (SOR_1220) frr 1195791..1196348 (-) 558 WP_001262235.1 ribosome recycling factor -

Sequence

Protein


Download         Length: 216 a.a.        Molecular weight: 23212.45 Da        Isoelectric Point: 6.5084

>NTDB_id=40204 SOR_RS05930 WP_000387358.1 1190960..1191610(-) (comEA/celA/cilE) [Streptococcus oralis Uo5]
MEAIIKKIKEYKIIVICAVLGLALGGFFLLKPTSQTPVKETNLQAEVAAVSKDSSSEKEVNKEEKEESTEQDLITVDVKG
AVKSPGIYDLPVGSRVHDAVQKAGGLTEEADSKSLNLAQKVSDEALVYVPTKGEEIASQQATSGTSPSTSKDKKVNLNKA
SLEELKQVKGLGGKRAQDIIDHREANGKFKSVDELKKVSGIGAKTIEKLKDYVTVD

Nucleotide


Download         Length: 651 bp        

>NTDB_id=40204 SOR_RS05930 WP_000387358.1 1190960..1191610(-) (comEA/celA/cilE) [Streptococcus oralis Uo5]
ATGGAAGCAATTATCAAGAAAATAAAAGAGTATAAAATCATTGTCATCTGTGCTGTTTTAGGTTTGGCCTTGGGCGGATT
TTTCCTACTAAAGCCAACTTCACAAACACCTGTCAAGGAAACGAATTTGCAGGCTGAAGTCGCAGCTGTTTCAAAGGATT
CATCATCTGAAAAAGAAGTGAACAAGGAAGAAAAGGAAGAATCTACTGAACAAGATCTAATCACAGTAGATGTCAAGGGT
GCCGTTAAATCACCCGGGATTTACGATTTGCCAGTAGGAAGTCGGGTTCACGATGCAGTTCAGAAAGCTGGTGGATTGAC
AGAGGAAGCAGACAGCAAGTCGCTTAATCTCGCTCAGAAAGTCAGTGACGAGGCTCTTGTCTATGTTCCAACCAAGGGAG
AAGAAATAGCTAGTCAGCAGGCTACCTCTGGAACGTCTCCTTCGACAAGTAAAGATAAGAAGGTCAATCTCAATAAAGCT
AGTCTGGAAGAACTCAAGCAGGTCAAAGGCTTGGGAGGAAAACGAGCTCAGGATATTATCGACCATCGCGAGGCAAATGG
CAAATTCAAGTCGGTAGATGAATTAAAGAAAGTCTCTGGCATTGGCGCTAAGACCATAGAAAAGTTAAAAGACTATGTTA
CAGTGGATTAA

Domains

Predicted by InterproScan.

Helix-hairpin-helix motif (HHH_3)

(152-214)

SLBB domain (SLBB)

(76-126)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB F2QE03

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comEA/celA/cilE Streptococcus mitis NCTC 12261

90.741

100

0.907
  comEA/celA/cilE Streptococcus pneumoniae TIGR4

90.278

100

0.903
  comEA/celA/cilE Streptococcus pneumoniae D39

89.352

100

0.894
  comEA/celA/cilE Streptococcus pneumoniae R6

89.352

100

0.894
  comEA/celA/cilE Streptococcus pneumoniae Rx1

89.352

100

0.894
  comEA/celA/cilE Streptococcus mitis SK321

87.5

100

0.875
  comEA Lactococcus lactis subsp. cremoris KW2

41.441

100

0.426
  comEA Latilactobacillus sakei subsp. sakei 23K

34.335

100

0.37

Multiple sequence alignment