Detailed information NTG0040203

Bioinformatically predicted

Overview

• Name: comEC/celB
• Type: Machinery gene
• Locus tag: SOR_RS05925
• Genome accession: NC_015291
• Coordinates: 1188736..1190976 (-)
• Length: 746 a.a.
• NCBI ID: WP_000942376.1
• Uniprot ID: -
• Organism: Streptococcus oralis Uo5
• Function: ssDNA transport into the cell (predicted from homology) DNA binding and uptake

Genomic Context

Location: 1183736..1195976

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
SOR_RS05905 (SOR_1209)	-	1185502..1187166 (-)	1665	WP_000635030.1	molecular chaperone HscC	-
SOR_RS05910 (SOR_1210)	rplT	1187342..1187701 (-)	360	WP_000124830.1	50S ribosomal protein L20	-
SOR_RS05915 (SOR_1211)	rpmI	1187753..1187953 (-)	201	WP_001125942.1	50S ribosomal protein L35	-
SOR_RS05920 (SOR_1212)	infC	1187986..1188516 (-)	531	WP_000848184.1	translation initiation factor IF-3	-
SOR_RS05925 (SOR_1213)	comEC/celB	1188736..1190976 (-)	2241	WP_000942376.1	DNA internalization-related competence protein ComEC/Rec2	Machinery gene
SOR_RS05930 (SOR_1214)	comEA/celA/cilE	1190960..1191610 (-)	651	WP_000387358.1	helix-hairpin-helix domain-containing protein	Machinery gene
SOR_RS05935 (SOR_1215)	-	1191677..1192246 (-)	570	WP_000443901.1	GNAT family N-acetyltransferase	-
SOR_RS05940 (SOR_1216)	ald	1192423..1193541 (+)	1119	WP_000904695.1	alanine dehydrogenase	-
SOR_RS05945 (SOR_1217)	-	1193586..1194572 (-)	987	WP_000658194.1	PhoH family protein	-
SOR_RS05950 (SOR_1218)	-	1194653..1194868 (-)	216	WP_001232089.1	YozE family protein	-
SOR_RS05955 (SOR_1219)	cvfB	1194877..1195731 (-)	855	WP_001095427.1	RNA-binding virulence regulatory protein CvfB	-

Sequence

Protein

• Length: 746 a.a.
• Molecular weight: 84642.80 Da
• Isoelectric Point: 8.8911

>NTDB_id=40203 SOR_RS05925 WP_000942376.1 1188736..1190976(-) (comEC/celB) [Streptococcus oralis Uo5]
MLQWIKNFPIPLIYLSFLLLWLYYAIFGASYLALLGFVFLLVCLFFQFPWKSAGKVLAICGVFGFWFLFQNWQQTQANQN
LVDSVERVRILPDTIKVNGDSLSFRGKADGRTFQVYYKLQSEEEKEHFQALTDLYEIELEGKLSEPEGQRNFGGFDYQAY
LKTQGIYQTLTIKSIQSLKQVSSWDIGENLSSLRRKAIVWIKSHFPDPMRNYMTGLLLGHLDTDFEEMNELYSSLGIIHL
FALSGMQVGFFMDAFKKLLLRLGLTQEKLKWLTYPFSLIYAGLTGFSASVIRSLLQKLLAQHGYKGLDNFALTVLVLFII
MPNFFLTAGGVLSCAYAFILTMTSKEGDGIKAVARESLVISLGILPILSFYFAEFQPWSILLTFVFSFLFDVVFLPLLSI
LFILSFVYPVTQLNLVFEWLEGIIRLVSQLASRPLVFGQPTAWLLILLLVSLALVYDMRKNVKRLAGFSLFIVGLFFLTK
HPLENEITMLDVGQGESIFLRDVTGKIILIDVGGRAESDKKIEKWQEKATTSNAQRTLIPYLKSRGVDKIDQLILTNTDK
EHVGDLLEVTKAFHVGEILVSKGSLTQKEFVAELEASQNMVRSVTAGENFSIFGSQLEVLSPRKIGDGDRDASLILYGKL
LDKHFLFTGNLKAKGEKDLMKHYPDLEVDVLKAGQHGAKTSSNPAFLEQLKPEITLISVGKNNRAKLPHQETLTQLENIK
SKIYRTDQQGAIRFKGWNSWRIETVR

Nucleotide

• Length: 2241 bp

>NTDB_id=40203 SOR_RS05925 WP_000942376.1 1188736..1190976(-) (comEC/celB) [Streptococcus oralis Uo5]
ATGTTACAGTGGATTAAGAATTTCCCTATCCCCCTAATCTATCTGAGCTTTCTGTTACTCTGGCTTTACTATGCCATTTT
TGGAGCGTCCTATCTCGCACTGCTAGGTTTTGTTTTTTTGCTTGTCTGTCTCTTTTTCCAATTTCCTTGGAAATCGGCTG
GTAAAGTTTTAGCGATTTGTGGAGTCTTTGGCTTTTGGTTTTTGTTTCAAAATTGGCAACAGACACAAGCTAATCAAAAC
CTAGTGGATTCTGTTGAAAGGGTACGGATTTTACCAGATACTATCAAGGTCAATGGAGATAGTCTGTCCTTTCGGGGCAA
GGCTGACGGTCGTACCTTCCAAGTTTACTATAAACTCCAGTCCGAGGAGGAGAAAGAGCACTTTCAAGCCTTGACAGACC
TTTATGAGATTGAACTAGAAGGAAAACTTTCCGAGCCAGAAGGCCAGAGAAATTTTGGTGGATTTGACTACCAAGCCTAT
CTGAAGACTCAGGGGATTTACCAGACACTGACTATTAAGAGCATCCAGTCACTTAAACAGGTTAGCAGTTGGGATATAGG
TGAAAACCTATCGAGTCTACGTAGAAAGGCTATTGTTTGGATTAAGAGCCATTTTCCCGACCCTATGCGTAACTACATGA
CGGGGCTCTTGCTGGGACATTTGGACACGGACTTTGAGGAGATGAATGAGCTCTATTCCAGTCTTGGAATTATTCATCTT
TTTGCCTTGTCGGGTATGCAGGTGGGCTTTTTCATGGATGCCTTTAAGAAACTTCTCTTACGATTGGGCTTGACCCAAGA
AAAGTTGAAGTGGCTGACTTATCCCTTTTCTCTTATTTATGCTGGTCTGACAGGATTTTCAGCATCGGTCATTCGCAGTC
TCTTGCAAAAGTTACTGGCCCAACATGGCTACAAGGGTTTGGATAATTTTGCCTTGACGGTCCTTGTCCTCTTTATCATC
ATGCCCAACTTTTTCTTGACAGCAGGAGGAGTCTTGTCTTGCGCTTATGCTTTTATCTTGACCATGACTAGCAAAGAAGG
CGATGGGATCAAGGCTGTTGCCAGAGAAAGTTTGGTCATTTCTTTGGGAATATTGCCCATTCTATCCTTTTATTTTGCAG
AATTTCAGCCTTGGTCTATTCTTTTGACCTTTGTCTTTTCCTTTCTGTTTGATGTAGTATTCTTACCACTTTTGTCTATC
TTATTCATTCTGTCTTTTGTTTACCCAGTCACTCAGCTTAACCTTGTCTTTGAATGGTTGGAGGGCATCATTCGCTTGGT
ATCGCAGCTGGCAAGCAGACCACTGGTCTTTGGTCAACCCACCGCATGGCTTTTGATTCTTCTCTTAGTTTCATTAGCCT
TGGTCTATGACATGAGGAAAAATGTCAAAAGACTAGCAGGATTCAGTCTCTTTATCGTGGGTCTCTTTTTCTTGACCAAG
CATCCACTTGAAAATGAAATCACCATGCTAGATGTGGGGCAAGGTGAAAGTATTTTCCTACGGGATGTGACTGGTAAAAT
CATTCTCATAGATGTCGGTGGCAGGGCAGAGTCTGATAAGAAAATCGAAAAATGGCAAGAAAAGGCGACGACCAGCAATG
CTCAGCGCACCTTGATTCCCTATCTAAAAAGTCGAGGAGTAGATAAGATTGATCAGCTGATTTTGACCAACACAGATAAA
GAACATGTTGGAGATTTGCTGGAGGTGACCAAGGCTTTCCATGTCGGGGAGATTTTAGTATCAAAAGGAAGTCTGACACA
GAAGGAATTTGTAGCGGAACTAGAAGCAAGTCAAAACATGGTACGTAGTGTGACAGCTGGGGAGAATTTCTCGATTTTTG
GGAGTCAGTTAGAAGTCCTATCTCCAAGGAAAATTGGAGATGGGGATCGTGATGCTTCCCTGATTCTTTATGGAAAACTT
TTGGATAAGCACTTTCTCTTTACTGGAAATTTGAAAGCGAAGGGAGAGAAGGACTTGATGAAGCACTATCCTGACCTAGA
GGTGGATGTCTTGAAAGCAGGCCAACATGGTGCTAAAACCTCATCAAATCCAGCTTTCCTAGAACAGCTCAAACCAGAAA
TTACTCTCATCTCAGTTGGAAAAAACAATCGAGCAAAACTCCCTCATCAGGAAACCTTGACACAACTGGAAAATATCAAG
AGTAAGATTTACCGAACTGACCAGCAAGGAGCTATCCGCTTTAAAGGATGGAATAGTTGGAGAATTGAAACGGTTCGATA
A

Domains

Predicted by InterproScan.

• Domain of unknown function (DUF4131) (DUF4131) (31-177)

• Competence protein (Competence) (216-458)

• Metallo-beta-lactamase superfamily (Lactamase_B) (492-696)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comEC/celB	Streptococcus mitis NCTC 12261	88.591	99.866	0.885
comEC/celB	Streptococcus mitis SK321	88.472	100	0.885
comEC/celB	Streptococcus pneumoniae TIGR4	86.595	100	0.866
comEC/celB	Streptococcus pneumoniae Rx1	86.193	100	0.862
comEC/celB	Streptococcus pneumoniae D39	86.193	100	0.862
comEC/celB	Streptococcus pneumoniae R6	86.193	100	0.862
comEC	Lactococcus lactis subsp. cremoris KW2	45.209	99.33	0.449