Detailed information    

insolico Bioinformatically predicted

Overview

Name   micA   Type   Regulator
Locus tag   SOR_RS04635 Genome accession   NC_015291
Coordinates   918658..919365 (+) Length   235 a.a.
NCBI ID   WP_000722055.1    Uniprot ID   A0A7H9FCX0
Organism   Streptococcus oralis Uo5     
Function   repress competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 913658..924365
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SOR_RS04610 (SOR_0943) - 913956..914627 (+) 672 WP_000151550.1 GTP pyrophosphokinase family protein -
  SOR_RS04615 (SOR_0944) - 914611..915429 (+) 819 WP_000799065.1 NAD kinase -
  SOR_RS04620 (SOR_0945) - 915426..916322 (+) 897 WP_001210021.1 RluA family pseudouridine synthase -
  SOR_RS04625 (SOR_0946) pta 916366..917340 (+) 975 WP_000451575.1 phosphate acetyltransferase -
  SOR_RS04630 (SOR_0947) mutY 917423..918601 (+) 1179 WP_000886156.1 A/G-specific adenine glycosylase -
  SOR_RS04635 (SOR_0948) micA 918658..919365 (+) 708 WP_000722055.1 response regulator YycF Regulator
  SOR_RS04640 (SOR_0949) micB 919358..920707 (+) 1350 WP_000568722.1 cell wall metabolism sensor histidine kinase VicK Regulator
  SOR_RS04645 (SOR_0950) vicX 920709..921518 (+) 810 WP_001290609.1 MBL fold metallo-hydrolase Regulator
  SOR_RS04650 (SOR_0951) - 921553..921900 (-) 348 WP_000434657.1 thiol reductase thioredoxin -
  SOR_RS04655 (SOR_0952) - 922011..923729 (-) 1719 WP_000222129.1 phospho-sugar mutase -

Sequence

Protein


Download         Length: 235 a.a.        Molecular weight: 27005.85 Da        Isoelectric Point: 4.6177

>NTDB_id=40195 SOR_RS04635 WP_000722055.1 918658..919365(+) (micA) [Streptococcus oralis Uo5]
MKKILIVDDEKPISDIIKFNMAKEGYEVVTAFNGREAIELFEAEQPDIIILDLMLPEIDGLEVAKAIRKTSSVPIIMLSA
KDSEFDKVIGLELGADDYVTKPFSNRELQARVKALLRRTDIVSVDSQESDEKKTQPLQIGDLEIVPDAYVAKKYGEELDL
THREFELLYHLASHIGQVITREHLLETVWGYDYFGDVRTVDVTIRRLREKIEDTPSRPEYILTRRGVGYYMRNND

Nucleotide


Download         Length: 708 bp        

>NTDB_id=40195 SOR_RS04635 WP_000722055.1 918658..919365(+) (micA) [Streptococcus oralis Uo5]
ATGAAAAAAATATTAATTGTTGATGATGAGAAACCAATCTCAGATATTATTAAGTTTAATATGGCCAAGGAAGGTTATGA
AGTTGTTACAGCCTTCAATGGTCGTGAGGCAATCGAGCTATTTGAAGCAGAGCAACCAGATATTATTATCCTCGACTTGA
TGCTACCTGAAATTGATGGTTTAGAAGTTGCTAAAGCTATTCGTAAGACTAGTAGCGTGCCGATTATCATGCTATCAGCT
AAGGATAGCGAATTTGACAAGGTTATTGGTTTAGAGTTAGGTGCAGACGATTATGTTACAAAACCTTTCTCAAACCGTGA
GTTGCAAGCACGTGTTAAGGCTCTGCTTCGTCGTACAGACATAGTTTCTGTGGATAGCCAAGAGTCCGATGAGAAGAAGA
CGCAACCTTTACAAATTGGTGATTTGGAAATCGTTCCAGATGCTTACGTGGCTAAGAAATATGGTGAGGAATTAGATTTG
ACCCACCGTGAGTTTGAACTCTTGTATCACTTGGCGTCTCATATTGGTCAAGTGATTACACGTGAACACTTGCTTGAGAC
TGTATGGGGTTATGACTATTTTGGTGATGTTCGTACAGTGGACGTGACCATTAGACGCTTGCGTGAGAAAATAGAAGACA
CTCCAAGTCGCCCAGAGTACATTCTCACACGTCGTGGTGTTGGCTACTATATGAGAAATAATGATTGA

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(4-112)

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(155-230)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A7H9FCX0

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  micA Streptococcus pneumoniae Cp1015

92.308

99.574

0.919
  vicR Streptococcus mutans UA159

77.447

100

0.774
  covR Streptococcus salivarius strain HSISS4

44.156

98.298

0.434
  covR Lactococcus lactis subsp. lactis strain DGCC12653

43.29

98.298

0.426
  scnR Streptococcus mutans UA159

37.179

99.574

0.37

Multiple sequence alignment