Detailed information NTG0040196

Bioinformatically predicted

Overview

• Name: micB
• Type: Regulator
• Locus tag: SOR_RS04640
• Genome accession: NC_015291
• Coordinates: 919358..920707 (+)
• Length: 449 a.a.
• NCBI ID: WP_000568722.1
• Uniprot ID: F2QD90
• Organism: Streptococcus oralis Uo5
• Function: repress competence development (predicted from homology) Competence regulation

Genomic Context

Location: 914358..925707

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
SOR_RS04615 (SOR_0944)	-	914611..915429 (+)	819	WP_000799065.1	NAD kinase	-
SOR_RS04620 (SOR_0945)	-	915426..916322 (+)	897	WP_001210021.1	RluA family pseudouridine synthase	-
SOR_RS04625 (SOR_0946)	pta	916366..917340 (+)	975	WP_000451575.1	phosphate acetyltransferase	-
SOR_RS04630 (SOR_0947)	mutY	917423..918601 (+)	1179	WP_000886156.1	A/G-specific adenine glycosylase	-
SOR_RS04635 (SOR_0948)	micA	918658..919365 (+)	708	WP_000722055.1	response regulator YycF	Regulator
SOR_RS04640 (SOR_0949)	micB	919358..920707 (+)	1350	WP_000568722.1	cell wall metabolism sensor histidine kinase VicK	Regulator
SOR_RS04645 (SOR_0950)	vicX	920709..921518 (+)	810	WP_001290609.1	MBL fold metallo-hydrolase	Regulator
SOR_RS04650 (SOR_0951)	-	921553..921900 (-)	348	WP_000434657.1	thiol reductase thioredoxin	-
SOR_RS04655 (SOR_0952)	-	922011..923729 (-)	1719	WP_000222129.1	phospho-sugar mutase	-
SOR_RS04660 (SOR_0954)	-	924140..925293 (+)	1154	Protein_874	DUF4352 domain-containing protein	-

Sequence

Protein

• Length: 449 a.a.
• Molecular weight: 51621.98 Da
• Isoelectric Point: 4.5796

>NTDB_id=40196 SOR_RS04640 WP_000568722.1 919358..920707(+) (micB) [Streptococcus oralis Uo5]
MIEDIRQTILTSDFIFILILLGFILVVTLLLLENRRDNIRLKEINQKVKDLIAGDYSQVLDLQGSTEITNITNNLNDLSE
VIRLTQENLEQESKRLNSILSYMTDGVLATNRRGQITMINDMAKKQLGVQKEDVLNKSILELLKIEDEYELRDLITQIPE
LTIDSQDVNGEYLSLRVRFALVRRESGFISGLVAVLHDTTEQEKEERERRLFVSNVSHELRTPLTSVKSYLEALDEGALY
DPVAPDFIKVSLDETNRMMRMVTDLLHLSRIDNTTSQLDVELINFTAFITFILNRFDKMRSQDEEKKYELVRDYPINSVW
IEIDTDKMTQVIDNILNNAIKYSPDGGKITVSMKTTDDQMILSIKDQGLGIPKQDLPKIFDRFYRVDRARSRAQGGTGLG
LAIAKEIIKQHNGFIWAKSEYGKGSTFTIVLPYDKDAVKEEIWEDEIED

Nucleotide

• Length: 1350 bp

>NTDB_id=40196 SOR_RS04640 WP_000568722.1 919358..920707(+) (micB) [Streptococcus oralis Uo5]
ATGATTGAAGATATTAGACAAACTATTCTGACCAGCGATTTTATCTTTATCCTGATTTTACTTGGTTTTATCTTGGTAGT
GACCTTGCTGTTACTGGAAAATCGTCGGGATAATATCCGTCTAAAGGAGATAAATCAAAAGGTGAAGGACTTGATTGCAG
GTGATTATTCTCAAGTTTTGGACTTGCAAGGAAGTACAGAAATCACCAATATCACCAATAATCTGAACGATTTGTCAGAA
GTTATTCGTTTGACCCAAGAAAATCTGGAACAAGAGAGTAAACGATTGAACAGTATTCTTTCTTACATGACAGATGGCGT
TCTTGCGACTAATCGCCGCGGCCAGATTACTATGATCAACGATATGGCCAAGAAACAGCTCGGAGTGCAGAAAGAAGATG
TTCTGAATAAAAGCATCCTCGAATTGCTTAAGATAGAAGATGAGTATGAGCTGCGTGATCTGATTACACAGATTCCTGAG
TTGACGATTGACTCCCAGGATGTAAATGGTGAATACCTGAGCCTTCGTGTCCGTTTTGCTCTGGTTCGCCGTGAGTCAGG
TTTCATCTCTGGTTTGGTTGCCGTTTTACATGATACGACCGAACAGGAGAAGGAAGAGCGTGAGCGAAGACTCTTTGTTT
CGAACGTGAGTCACGAGTTGCGAACTCCTTTGACCAGTGTTAAATCTTATCTTGAAGCCTTGGACGAGGGAGCTCTGTAT
GATCCTGTTGCACCTGATTTTATCAAGGTTTCACTCGATGAAACCAACCGTATGATGCGGATGGTAACAGATCTCTTGCA
TCTCTCTCGTATTGATAATACGACAAGTCAGCTAGATGTGGAATTGATTAATTTTACAGCATTCATCACCTTTATTCTCA
ACCGCTTTGATAAGATGAGGAGCCAGGATGAAGAGAAAAAATATGAACTTGTTAGAGATTATCCAATTAATTCAGTTTGG
ATTGAGATTGATACCGATAAGATGACTCAGGTGATTGATAATATTCTTAACAATGCCATCAAGTACTCACCAGATGGCGG
CAAAATTACTGTTAGCATGAAGACCACTGATGACCAGATGATTTTATCCATCAAAGACCAAGGTCTAGGTATTCCAAAGC
AAGATTTGCCGAAGATCTTTGACCGCTTCTACCGTGTGGATCGTGCAAGAAGCCGGGCTCAAGGTGGAACTGGTCTAGGT
CTAGCCATCGCAAAAGAAATCATCAAACAACACAATGGCTTTATATGGGCCAAAAGTGAATACGGTAAGGGATCGACCTT
TACCATAGTGCTCCCTTATGATAAGGATGCCGTAAAAGAAGAAATATGGGAGGACGAAATAGAAGACTAG

Domains

Predicted by InterproScan.

• His Kinase A (phospho-acceptor) domain (HisKA) (209-273)

• PAS fold (PAS) (95-198)

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (324-434)

3D structure

• AlphaFold DB: F2QD90

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
micB	Streptococcus pneumoniae Cp1015	89.294	97.773	0.873
vicK	Streptococcus mutans UA159	70.896	89.532	0.635