Detailed information NTG0401463

Bioinformatically predicted

Overview

• Name: clpP
• Type: Regulator
• Locus tag: GKC27_RS16875
• Genome accession: NZ_CP046130
• Coordinates: 3237745..3238341 (+)
• Length: 198 a.a.
• NCBI ID: WP_003212962.1
• Uniprot ID: A0A081LFM4
• Organism: Bacillus pumilus strain DSM 27
• Function: degradation of ComK; degradation of DegU (predicted from homology) Competence regulation

Genomic Context

Location: 3232745..3243341

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
GKC27_RS16850 (GKC27_16660)	abc-f	3232769..3234328 (-)	1560	WP_003212762.1	ABC-F type ribosomal protection protein	-
GKC27_RS16855 (GKC27_16665)	-	3234820..3235989 (-)	1170	WP_003213609.1	macrolide family glycosyltransferase	-
GKC27_RS16860 (GKC27_16670)	-	3236251..3236715 (-)	465	WP_003212622.1	DinB family protein	-
GKC27_RS16870 (GKC27_16680)	-	3237211..3237489 (-)	279	WP_003212776.1	TM2 domain-containing protein	-
GKC27_RS16875 (GKC27_16685)	clpP	3237745..3238341 (+)	597	WP_003212962.1	ATP-dependent Clp endopeptidase proteolytic subunit ClpP	Regulator
GKC27_RS16880 (GKC27_16690)	-	3238401..3238979 (-)	579	WP_034620142.1	TIGR00730 family Rossman fold protein	-
GKC27_RS16885 (GKC27_16695)	-	3239116..3239445 (+)	330	WP_003213115.1	MazG-like family protein	-
GKC27_RS16890 (GKC27_16700)	-	3239474..3241096 (-)	1623	WP_003213243.1	SulP family inorganic anion transporter	-
GKC27_RS16895 (GKC27_16705)	-	3241134..3241715 (-)	582	WP_003213318.1	carbonic anhydrase	-
GKC27_RS16900 (GKC27_16710)	-	3242269..3243246 (+)	978	WP_003213741.1	D-glycerate dehydrogenase	-

Sequence

Protein

• Length: 198 a.a.
• Molecular weight: 21816.00 Da
• Isoelectric Point: 4.6905

>NTDB_id=401463 GKC27_RS16875 WP_003212962.1 3237745..3238341(+) (clpP) [Bacillus pumilus strain DSM 27]
MNLIPTVIEQTNRGERAYDIYSRLLKDRIIMLGSAIDDNVANSIVSQLLFLEAEDPEKDISIYINSPGGSITAGMAIYDT
MQFIKPKVSTICIGMAASMGAFLLAAGEKGKRYALPNSEVMIHQPLGGAQGQATEIEIAAKRILSLRDKLNQVLAERTGQ
PIEVIERDTDRDNFKTAEEALQYGLIDKVLTRNAEEQK

Nucleotide

• Length: 597 bp

>NTDB_id=401463 GKC27_RS16875 WP_003212962.1 3237745..3238341(+) (clpP) [Bacillus pumilus strain DSM 27]
ATGAATTTAATACCTACAGTCATTGAACAAACAAATCGTGGGGAAAGAGCTTACGACATTTATTCTCGTCTTTTAAAAGA
CCGTATTATCATGCTTGGTTCTGCGATCGATGACAATGTTGCCAACTCCATCGTGTCCCAGCTGCTTTTCTTAGAAGCTG
AAGATCCAGAAAAAGATATTTCTATCTACATTAACAGCCCTGGCGGTTCAATCACAGCTGGTATGGCCATTTACGATACG
ATGCAATTTATTAAACCAAAGGTATCAACCATTTGTATTGGTATGGCTGCATCTATGGGTGCGTTCCTGCTTGCTGCTGG
TGAAAAAGGTAAGCGTTATGCTCTTCCAAACAGTGAAGTCATGATTCACCAACCACTAGGTGGTGCCCAAGGTCAAGCAA
CAGAAATTGAAATTGCGGCAAAACGAATCCTTTCTTTACGCGATAAACTGAACCAAGTACTTGCTGAACGCACTGGTCAG
CCAATCGAAGTGATTGAGCGCGATACAGATCGTGACAACTTCAAAACAGCGGAAGAAGCACTTCAATACGGACTCATTGA
CAAAGTCTTGACCCGTAATGCAGAAGAACAAAAATAA

Domains

Predicted by InterproScan.

• Clp protease (CLP_protease) (13-192)

3D structure

• AlphaFold DB: A0A081LFM4

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpP	Bacillus subtilis subsp. subtilis str. 168	92.386	99.495	0.919
clpP	Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819	67.539	96.465	0.652
clpP	Streptococcus thermophilus LMG 18311	58.549	97.475	0.571
clpP	Streptococcus thermophilus LMD-9	58.549	97.475	0.571
clpP	Lactococcus lactis subsp. cremoris KW2	56.186	97.98	0.551
clpP	Streptococcus pneumoniae Rx1	55.67	97.98	0.545
clpP	Streptococcus pneumoniae D39	55.67	97.98	0.545
clpP	Streptococcus pneumoniae R6	55.67	97.98	0.545
clpP	Streptococcus pneumoniae TIGR4	55.67	97.98	0.545
clpP	Streptococcus pyogenes JRS4	55.44	97.475	0.54
clpP	Streptococcus pyogenes MGAS315	55.44	97.475	0.54
clpP	Streptococcus mutans UA159	54.639	97.98	0.535
clpP	Lactococcus lactis subsp. lactis strain DGCC12653	54.124	97.98	0.53