Detailed information NTG0400498

Bioinformatically predicted

Overview

• Name: comR
• Type: Regulator
• Locus tag: GJS33_RS00280
• Genome accession: NZ_CP046041
• Coordinates: 47764..48678 (+)
• Length: 304 a.a.
• NCBI ID: WP_111692077.1
• Uniprot ID: -
• Organism: Streptococcus equi subsp. zooepidemicus strain AZ-45470
• Function: activate transcription of comX (predicted from homology) Competence regulation

Genomic Context

Location: 42764..53678

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
GJS33_RS00260 (GJS33_00260)	purE	43917..44405 (+)	489	WP_111692074.1	5-(carboxyamino)imidazole ribonucleotide mutase	-
GJS33_RS00265 (GJS33_00265)	purK	44392..45486 (+)	1095	WP_154298634.1	5-(carboxyamino)imidazole ribonucleotide synthase	-
GJS33_RS00270 (GJS33_00270)	-	45496..45720 (+)	225	WP_012514713.1	hypothetical protein	-
GJS33_RS10025	-	45763..46035 (+)	273	WP_372585987.1	hypothetical protein	-
GJS33_RS00275 (GJS33_00275)	purB	46174..47466 (+)	1293	WP_111692076.1	adenylosuccinate lyase	-
GJS33_RS00280 (GJS33_00280)	comR	47764..48678 (+)	915	WP_111692077.1	helix-turn-helix domain-containing protein	Regulator
GJS33_RS10030	comS	48761..48859 (+)	99	WP_021320241.1	quorum-sensing system DWW-type pheromone	Regulator
GJS33_RS00285 (GJS33_00285)	ruvB	48893..49894 (+)	1002	WP_012514715.1	Holliday junction branch migration DNA helicase RuvB	-
GJS33_RS00290 (GJS33_00290)	-	50142..50600 (+)	459	WP_111692078.1	low molecular weight protein-tyrosine-phosphatase	-
GJS33_RS00295 (GJS33_00295)	-	50606..51007 (+)	402	WP_012514718.1	MORN repeat-containing protein	-
GJS33_RS00300 (GJS33_00300)	-	51004..52785 (+)	1782	WP_043029239.1	acyltransferase family protein	-

Sequence

Protein

• Length: 304 a.a.
• Molecular weight: 35790.34 Da
• Isoelectric Point: 4.5517

>NTDB_id=400498 GJS33_RS00280 WP_111692077.1 47764..48678(+) (comR) [Streptococcus equi subsp. zooepidemicus strain AZ-45470]
MLDNFGEKVRDLRYQKKITREDLCGDESELSIRQLARIELGQSIPSLSKVVFIAKALDVSVGFLTDGEDLELPKRYKELK
YLILRTPTYMDDDKLKLREEQFDEIFEDYYDQLPEEEKLVVDCLQSIMDTLLTENINFGVGLLQEYFEQTKSKTQFREND
LILIELYLAYLDIAGMNGEYSDKGFYDSLLDILLNQFEHFELEELFIVNKIAIGISSLSIKNNKPEILEKVIVLSQKIIL
KTQDFNRMPILNLIEWKYALMKKKDIEMAKKCYDKACLFAQLTGDQYLEKKLREEWGKDIKRYQ

Nucleotide

• Length: 915 bp

>NTDB_id=400498 GJS33_RS00280 WP_111692077.1 47764..48678(+) (comR) [Streptococcus equi subsp. zooepidemicus strain AZ-45470]
ATGTTAGACAATTTTGGTGAAAAGGTGAGAGACCTGCGGTATCAGAAGAAGATTACCAGAGAGGATTTATGTGGAGATGA
GTCAGAATTATCCATTCGTCAATTAGCACGAATAGAATTGGGCCAATCGATTCCCAGCCTATCAAAGGTGGTTTTTATTG
CTAAGGCTCTGGACGTTAGTGTCGGCTTTTTGACAGACGGAGAGGATTTGGAACTGCCTAAGCGTTATAAAGAACTTAAA
TATTTGATTTTAAGAACGCCGACCTATATGGATGATGACAAATTAAAGCTGCGAGAAGAGCAATTTGACGAAATTTTTGA
AGATTATTATGACCAGTTGCCAGAGGAAGAAAAGCTTGTGGTGGATTGCTTGCAGTCCATAATGGATACGTTATTAACCG
AGAATATCAATTTTGGAGTTGGGTTATTACAGGAATACTTTGAACAAACAAAAAGTAAGACTCAATTTAGAGAGAATGAT
CTCATTCTTATTGAGCTGTATTTAGCGTACCTCGACATTGCAGGAATGAATGGAGAGTATTCAGATAAAGGATTCTATGA
TTCTTTGTTAGACATTTTGTTAAATCAGTTTGAACATTTTGAATTAGAGGAATTATTTATTGTCAATAAAATAGCTATAG
GAATTTCCTCGTTGAGTATCAAAAACAATAAGCCGGAGATTCTTGAGAAGGTTATTGTACTTAGTCAAAAAATTATCCTC
AAGACTCAGGATTTTAATAGAATGCCTATCTTAAATTTGATAGAGTGGAAATATGCTCTAATGAAGAAAAAAGACATAGA
AATGGCCAAAAAATGCTATGATAAGGCATGCCTGTTTGCTCAATTAACAGGAGATCAGTATTTGGAAAAGAAATTGAGAG
AAGAATGGGGTAAAGATATAAAACGATATCAATAG

Domains

Predicted by InterproScan.

• ComR tetratricopeptide (ComR_TPR) (73-296)

• Helix-turn-helix domain (HTH_19) (6-69)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comR	Streptococcus pyogenes MGAS8232	74.587	99.671	0.743
comR	Streptococcus pyogenes MGAS315	54.817	99.013	0.543
comR	Streptococcus infantarius subsp. infantarius ATCC BAA-102	52.069	95.395	0.497
comR	Streptococcus mutans UA159	49.164	98.355	0.484
comR	Streptococcus suis D9	37.542	99.013	0.372
comR	Streptococcus suis 05ZYH33	38.305	97.039	0.372
comR	Streptococcus suis P1/7	38.305	97.039	0.372