Detailed information    

insolico Bioinformatically predicted

Overview

Name   comA/nlmT   Type   Regulator
Locus tag   GJE16_RS02475 Genome accession   NZ_CP045931
Coordinates   473928..475604 (-) Length   558 a.a.
NCBI ID   WP_196300924.1    Uniprot ID   -
Organism   Streptococcus pneumoniae strain AUSMDU00010538     
Function   transport of ComC (predicted from homology)   
Competence regulation

Genomic Context

Location: 468928..480604
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  GJE16_RS02445 (GJE16_02445) - 469261..469590 (-) 330 WP_000132572.1 hypothetical protein -
  GJE16_RS02450 (GJE16_02450) - 469866..470204 (+) 339 WP_000876675.1 LytTR family DNA-binding domain-containing protein -
  GJE16_RS02455 (GJE16_02455) comE/blpR 470254..470946 (+) 693 WP_223716556.1 response regulator transcription factor Regulator
  GJE16_RS02460 (GJE16_02460) - 470960..472300 (+) 1341 WP_050073044.1 sensor histidine kinase -
  GJE16_RS02465 (GJE16_02465) blpC 472371..472499 (-) 129 WP_000358815.1 quorum-sensing system pheromone BlpC -
  GJE16_RS02470 (GJE16_02470) - 472556..473917 (-) 1362 WP_001069060.1 bacteriocin secretion accessory protein -
  GJE16_RS02475 (GJE16_02475) comA/nlmT 473928..475604 (-) 1677 WP_196300924.1 peptide cleavage/export ABC transporter Regulator
  GJE16_RS11285 comA/nlmT 475498..476085 (-) 588 WP_000205166.1 cysteine peptidase family C39 domain-containing protein Regulator
  GJE16_RS02480 (GJE16_02480) blpI 476367..476564 (+) 198 WP_001093259.1 bacteriocin-like peptide BlpI -
  GJE16_RS02485 (GJE16_02485) blpJ 477031..477300 (+) 270 WP_001093248.1 bacteriocin-like peptide BlpJ -
  GJE16_RS02490 (GJE16_02490) blpK 477369..477617 (+) 249 WP_047475057.1 bacteriocin-like peptide BlpK -
  GJE16_RS02495 (GJE16_02495) cipB 477861..478010 (+) 150 WP_001809846.1 bacteriocin-like peptide BlpO Regulator
  GJE16_RS11400 - 478046..478111 (+) 66 Protein_491 ComC/BlpC family peptide pheromone/bacteriocin -
  GJE16_RS02500 (GJE16_02500) - 478114..478233 (+) 120 WP_000346296.1 PncF family bacteriocin immunity protein -
  GJE16_RS02510 (GJE16_02510) - 478714..479072 (+) 359 Protein_493 immunity protein -
  GJE16_RS02515 (GJE16_02515) - 479701..480084 (+) 384 WP_000877381.1 hypothetical protein -

Sequence

Protein


Download         Length: 558 a.a.        Molecular weight: 62949.24 Da        Isoelectric Point: 6.7844

>NTDB_id=399395 GJE16_RS02475 WP_196300924.1 473928..475604(-) (comA/nlmT) [Streptococcus pneumoniae strain AUSMDU00010538]
MIFKQKSLIAYIVLSSLLVTIINIGGSYYLQGILDEYIPNQMKSTLGIISVGLVITYILQQVMSFSRDYLLTVLSQRLSI
DVILSYIRHIFELPMSFFATRRTGEIISRFTDANSIIDALASTILSLFLDVSILILVGGVLLAQNPNLFLLSLISIPIYM
FIIFSFMKPFEKMNHDVMQSNSMVSSAIIEDINGIETIKSLTSEENRYQNIDSEFVDYLEKSFKLSKYSILQTSLKQGTK
LVLNILILWFGAQLVMSSKISIGQLITFNTLFSYFTTPMENIINLQTKLQSAKVANNRLNEVYLVESEFQVQENPVHSHF
LMGDIEFDDLSYKYGFGRDTLTDINLTIKQGDKVSLVGVSGSGKTTLAKMIVNFFEPYKGHISINHQDIKNIDKKVLRRH
INYLPQQAYIFNGSILENLTLGGNHMISQEDILRACELAEIRQDIERMPMGYQTQLSDGAGLSGGQKQRIALARALLTKA
PVLILDEATSGLDVLTEKKVIDNLMSLTDKTILFVAHRLSIAERTNRVIVLDQGKIIEVGSHQELMQAQGFYHHLFNK

Nucleotide


Download         Length: 1677 bp        

>NTDB_id=399395 GJE16_RS02475 WP_196300924.1 473928..475604(-) (comA/nlmT) [Streptococcus pneumoniae strain AUSMDU00010538]
CTGATTTTCAAACAAAAATCTCTCATTGCTTACATTGTTCTCTCAAGCTTATTGGTCACTATTATCAATATAGGTGGTTC
TTACTATCTCCAAGGAATCTTGGATGAATACATTCCAAATCAGATGAAATCAACTTTAGGAATCATCTCAGTTGGTCTGG
TTATCACCTATATCCTCCAACAAGTCATGAGCTTCTCCAGAGATTATCTCCTAACCGTTCTGAGTCAGAGATTAAGTATT
GATGTGATTTTATCCTATATTCGCCATATTTTTGAACTTCCCATGTCTTTCTTTGCGACACGTCGTACAGGAGAAATCAT
TTCACGATTCACAGATGCTAACTCTATTATAGATGCCTTGGCTTCTACCATTCTTTCTCTTTTTCTGGATGTTTCTATTC
TGATTCTTGTAGGAGGCGTCTTACTGGCACAAAACCCTAATCTCTTCCTTCTTTCTCTTATTTCCATTCCTATATACATG
TTCATCATCTTTTCTTTTATGAAACCTTTCGAAAAAATGAACCATGATGTCATGCAAAGTAATTCTATGGTTAGCTCTGC
CATTATCGAAGATATCAACGGGATTGAAACTATAAAGTCGCTCACGAGTGAAGAAAATCGCTATCAAAATATAGACAGCG
AATTTGTAGATTATTTGGAAAAATCCTTTAAGCTCAGTAAATATTCTATTTTACAAACGAGTTTAAAGCAGGGAACAAAA
TTAGTTCTGAATATCCTTATCCTATGGTTTGGCGCTCAATTAGTCATGTCGAGTAAAATTTCTATCGGTCAGCTGATTAC
CTTTAACACACTTTTTTCTTACTTTACAACTCCTATGGAAAATATTATCAACCTCCAAACCAAACTCCAATCTGCGAAGG
TCGCTAATAACCGTTTGAACGAAGTCTATCTAGTCGAATCTGAATTTCAAGTTCAAGAAAACCCTGTCCATTCACATTTT
TTGATGGGCGATATTGAATTTGATGACCTTTCTTATAAGTATGGTTTTGGACGAGATACCTTAACAGATATTAATCTCAC
GATTAAACAAGGAGATAAGGTTAGCCTAGTTGGAGTTAGTGGTTCTGGTAAAACAACTTTAGCCAAAATGATTGTCAATT
TCTTTGAACCCTACAAAGGACATATTTCTATCAATCATCAGGATATTAAAAACATTGATAAAAAAGTCTTGCGCCGTCAT
ATTAATTACCTACCACAACAAGCCTATATCTTTAATGGCTCTATCTTGGAAAACTTAACTTTGGGCGGTAATCATATGAT
TAGCCAAGAAGATATTCTAAGAGCTTGTGAATTAGCTGAAATTCGTCAAGACATTGAAAGAATGCCTATGGGCTATCAAA
CTCAGCTCTCTGATGGAGCTGGTCTATCAGGAGGACAAAAGCAACGAATAGCCCTCGCTCGTGCTCTTTTAACTAAAGCT
CCTGTTTTAATACTAGACGAAGCTACTAGCGGTCTTGATGTCTTGACTGAGAAAAAGGTTATAGATAATCTTATGTCTCT
AACTGATAAAACCATTCTCTTTGTAGCCCATCGTCTCAGTATAGCCGAACGAACCAACCGTGTCATTGTTCTTGACCAGG
GGAAAATCATTGAAGTTGGTAGTCACCAAGAGTTAATGCAGGCGCAAGGTTTCTACCATCATCTATTCAATAAATAA

Domains

Predicted by InterproScan.

ABC transporter (ABC_tran)

(341-490)

ABC transporter transmembrane region (ABC_membrane)

(10-279)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comA/nlmT Streptococcus mutans UA159

73.07

99.821

0.729
  comA Streptococcus mitis NCTC 12261

67.563

100

0.676
  comA Streptococcus pneumoniae D39

67.204

100

0.672
  comA Streptococcus pneumoniae R6

67.204

100

0.672
  comA Streptococcus pneumoniae Rx1

67.204

100

0.672
  comA Streptococcus mitis SK321

67.025

100

0.67
  comA Streptococcus gordonii str. Challis substr. CH1

66.905

100

0.67
  comA Streptococcus pneumoniae TIGR4

66.846

100

0.668

Multiple sequence alignment