NTDB

Overview

Name	clpP	Type	Regulator
Locus tag	HPY12_RS04740	Genome accession	NZ_CP053794
Coordinates	1007968..1008594 (+)	Length	208 a.a.
NCBI ID	WP_000121678.1	Uniprot ID	A0AAW4GZF5
Organism	Vibrio cholerae strain W10G
Function	degradation of ComK; degradation of DegU (predicted from homology) Competence regulation

Genomic Context

Location: 1002968..1013594

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
HPY12_RS04725 (HPY12_04730)	-	1004269..1006062 (-)	1794	WP_001891957.1	sensor histidine kinase	-
HPY12_RS04730 (HPY12_04735)	-	1006052..1006270 (+)	219	WP_001881672.1	hypothetical protein	-
HPY12_RS04735 (HPY12_04740)	tig	1006561..1007862 (+)	1302	WP_001198441.1	trigger factor	-
HPY12_RS04740 (HPY12_04745)	clpP	1007968..1008594 (+)	627	WP_000121678.1	ATP-dependent Clp endopeptidase proteolytic subunit ClpP	Regulator
HPY12_RS04745 (HPY12_04750)	clpX	1008674..1009954 (+)	1281	WP_000130332.1	ATP-dependent protease ATP-binding subunit ClpX	Regulator
HPY12_RS04750 (HPY12_04755)	lon	1010077..1012437 (+)	2361	WP_001047611.1	endopeptidase La	-
HPY12_RS04755 (HPY12_04760)	-	1012621..1012893 (+)	273	WP_001044516.1	HU family DNA-binding protein	-

Sequence

Protein

Download Length: 208 a.a. Molecular weight: 23082.42 Da Isoelectric Point: 5.0426

                                >NTDB_id=394701 HPY12_RS04740 WP_000121678.1 1007968..1008594(+) (clpP) [Vibrio cholerae strain W10G]

MSYQEKNAMSPIFDALVPMVVEQTSRGERSYDIYSRLLKERVIFLTGQVEDHMANLVVAQLLFLESENPDKDIFLYINSP

GGSVTAGMSIYDTMQFIKPNVSTVCMGQACSMGAFLLAGGAPGKRYVLPNSRVMIHQPLGGFQGQASDIQIHAQEILTIK

NKLNRLLAEHTGQPIEVIERDTDRDNFMSADQAVEYGLVDAVLKHRGE

Nucleotide

Download Length: 627 bp

                                >NTDB_id=394701 HPY12_RS04740 WP_000121678.1 1007968..1008594(+) (clpP) [Vibrio cholerae strain W10G]

ATGAGCTACCAAGAAAAAAATGCAATGTCGCCCATTTTTGACGCACTCGTACCTATGGTGGTTGAACAAACCTCTCGTGG

TGAGCGTTCATACGACATCTATTCTCGCTTACTAAAAGAACGAGTGATTTTCTTAACCGGGCAAGTAGAAGATCACATGG

CAAACCTTGTCGTGGCTCAACTGCTTTTCTTAGAATCTGAAAACCCTGATAAAGATATTTTCCTTTACATCAACTCACCC

GGTGGCAGTGTCACTGCAGGGATGTCGATTTACGATACTATGCAGTTCATCAAGCCAAACGTGAGCACAGTGTGTATGGG

ACAAGCCTGTTCAATGGGCGCTTTCTTGCTTGCTGGTGGTGCACCGGGCAAGCGTTATGTACTGCCGAATTCTCGTGTCA

TGATTCACCAACCACTGGGTGGATTCCAAGGCCAAGCCTCTGATATTCAAATTCATGCTCAAGAAATTCTGACCATTAAA

AACAAACTGAACCGTTTGTTGGCAGAGCATACAGGCCAGCCAATCGAAGTGATTGAACGCGATACTGATCGTGATAACTT

CATGTCGGCAGATCAAGCAGTGGAATACGGTTTGGTGGATGCGGTGCTGAAACACCGTGGCGAGTAA

Domains

Predicted by InterProScan.

Clp protease (CLP_protease)

(26-205)

Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.

3D structure

Source	ID	Structure
AlphaFold DB	A0AAW4GZF5

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.

Visualization of predicted probability:

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	H_a-value
clpP	Bacillus subtilis subsp. subtilis str. 168	68.947	91.346	0.63
clpP	Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819	63.684	91.346	0.582
clpP	Streptococcus pneumoniae Rx1	54.167	92.308	0.5
clpP	Streptococcus pneumoniae D39	54.167	92.308	0.5
clpP	Streptococcus pneumoniae R6	54.167	92.308	0.5
clpP	Streptococcus pneumoniae TIGR4	54.167	92.308	0.5
clpP	Streptococcus thermophilus LMG 18311	53.125	92.308	0.49
clpP	Streptococcus thermophilus LMD-9	53.125	92.308	0.49
clpP	Streptococcus mutans UA159	51.813	92.788	0.481
clpP	Lactococcus lactis subsp. cremoris KW2	51.562	92.308	0.476
clpP	Streptococcus pyogenes JRS4	51.562	92.308	0.476
clpP	Streptococcus pyogenes MGAS315	51.562	92.308	0.476
clpP	Lactococcus lactis subsp. lactis strain DGCC12653	50	92.308	0.462

Detailed information NTG0394701