Detailed information NTG0394407

Bioinformatically predicted

Overview

• Name: braS
• Type: Regulator
• Locus tag: GBR75_RS13225
• Genome accession: NZ_CP045468
• Coordinates: 2677696..2678583 (-)
• Length: 295 a.a.
• NCBI ID: WP_000143422.1
• Uniprot ID: A0AB73JC73
• Organism: Staphylococcus aureus strain SAW1
• Function: promote expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 2672696..2683583

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
GBR75_RS13195 (GBR75_13455)	-	2672705..2672797 (+)	93	WP_010956583.1	hypothetical protein	-
GBR75_RS13200 (GBR75_13460)	-	2672905..2673402 (-)	498	WP_001065268.1	glutathione peroxidase	-
GBR75_RS13205 (GBR75_13465)	-	2673412..2673672 (-)	261	WP_011382405.1	hypothetical protein	-
GBR75_RS13210 (GBR75_13475)	-	2674054..2674167 (-)	114	WP_078065157.1	hypothetical protein	-
GBR75_RS13215 (GBR75_13480)	-	2674836..2676836 (-)	2001	WP_000776725.1	ABC transporter permease	-
GBR75_RS13220 (GBR75_13485)	-	2676833..2677588 (-)	756	WP_000923775.1	ABC transporter ATP-binding protein	-
GBR75_RS13225 (GBR75_13490)	braS	2677696..2678583 (-)	888	WP_000143422.1	nisin susceptibility-associated two-component system sensor histidine kinase NsaS	Regulator
GBR75_RS13230 (GBR75_13495)	braR	2678594..2679259 (-)	666	WP_000697884.1	nisin susceptibility-associated two-component system response regulator NsaR	Regulator
GBR75_RS13235 (GBR75_13500)	-	2679285..2679485 (-)	201	WP_000604725.1	hypothetical protein	-
GBR75_RS13240 (GBR75_13505)	-	2679683..2681107 (+)	1425	WP_000953738.1	alkaline phosphatase	-
GBR75_RS14320 (GBR75_13510)	-	2681167..2681268 (-)	102	WP_000731972.1	SE2200 family small protein	-
GBR75_RS13250 (GBR75_13515)	-	2681390..2681845 (-)	456	WP_000106183.1	MarR family winged helix-turn-helix transcriptional regulator	-
GBR75_RS13255 (GBR75_13520)	-	2682090..2682851 (-)	762	WP_000323448.1	alpha/beta hydrolase	-

Sequence

Protein

• Length: 295 a.a.
• Molecular weight: 34031.29 Da
• Isoelectric Point: 5.8962

>NTDB_id=394407 GBR75_RS13225 WP_000143422.1 2677696..2678583(-) (braS) [Staphylococcus aureus strain SAW1]
MTFLKSITQEIAIVIVIFALFGLMFYLYHLPLEAYLLALGVILLLLLIFIGIKYLSFVKTISQQQQIENLENALYQLKNE
QIEYKNDVESYFLTWVHQMKTPITAAQLLLERDEPNVVNRVRQEVIQIDNYTSLALSYLKLLNETSDISVTKISINNIIR
PIIMKYSIQFIDQKTKIHYEPCHHEVLTDVRWTSLMIEQLINNALKYARGKDIWIEFDEQSNQLYVKDNGVGISEADLPK
IFDKGYSGYNGQRQSNSSGIGLFIVKQISTHTNHPVSVVSKQNEGTTFTIQFPDE

Nucleotide

• Length: 888 bp

>NTDB_id=394407 GBR75_RS13225 WP_000143422.1 2677696..2678583(-) (braS) [Staphylococcus aureus strain SAW1]
ATGACCTTTCTTAAAAGTATTACTCAGGAAATAGCAATAGTCATAGTTATTTTTGCTTTATTTGGCTTAATGTTTTACCT
GTATCATTTGCCATTAGAAGCATATTTACTAGCACTTGGCGTTATTTTATTATTATTACTCATATTCATAGGTATTAAAT
ATTTAAGTTTTGTAAAAACTATAAGCCAACAACAACAAATTGAAAACTTAGAAAATGCGTTGTATCAGCTTAAAAATGAA
CAAATTGAATATAAAAATGATGTAGAGAGCTACTTTTTAACATGGGTACATCAAATGAAAACACCCATTACTGCAGCACA
ACTGTTACTTGAAAGAGATGAGCCTAATGTTGTGAATCGTGTTCGTCAAGAGGTTATTCAAATTGATAACTATACAAGTT
TAGCACTTAGTTATTTAAAGTTATTAAATGAAACTTCTGATATTTCTGTCACTAAAATTTCGATTAACAATATCATTCGC
CCAATTATTATGAAATATTCAATACAGTTTATTGATCAAAAAACAAAAATCCATTATGAACCTTGTCATCACGAAGTATT
AACTGACGTTAGATGGACCTCTTTAATGATAGAACAATTAATAAATAATGCACTTAAGTATGCGAGAGGTAAAGATATAT
GGATTGAATTTGATGAGCAATCCAATCAATTATACGTAAAAGATAATGGTGTTGGTATTAGTGAAGCGGACTTGCCTAAA
ATATTTGATAAGGGCTATTCAGGTTATAATGGCCAGCGCCAAAGTAACTCAAGTGGGATTGGTTTATTTATCGTAAAACA
AATTTCAACTCACACAAACCATCCTGTTTCAGTCGTATCTAAACAAAATGAGGGTACAACATTTACGATTCAATTTCCAG
ATGAATAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (191-294)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
braS	Staphylococcus aureus N315	98.983	100	0.99