Detailed information    

insolico Bioinformatically predicted

Overview

Name   comE   Type   Machinery gene
Locus tag   F8B64_RS03035 Genome accession   NZ_CP044497
Coordinates   603923..605260 (+) Length   445 a.a.
NCBI ID   WP_012055031.1    Uniprot ID   -
Organism   Haemophilus influenzae strain PittGG     
Function   type IV pilus biogenesis and function (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 598923..610260
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  F8B64_RS03010 (F8B64_03010) - 598988..601582 (-) 2595 WP_012055034.1 penicillin-binding protein 1A -
  F8B64_RS03015 (F8B64_03015) comA 601681..602478 (+) 798 WP_012055033.1 pilus assembly protein PilM Machinery gene
  F8B64_RS03020 (F8B64_03020) comB 602479..602985 (+) 507 WP_005693724.1 competence protein ComB Machinery gene
  F8B64_RS03025 (F8B64_03025) comC 602982..603503 (+) 522 WP_012055032.1 competence protein ComC Machinery gene
  F8B64_RS03030 (F8B64_03030) comD 603500..603913 (+) 414 WP_005693727.1 pilus assembly protein PilP Machinery gene
  F8B64_RS03035 (F8B64_03035) comE 603923..605260 (+) 1338 WP_012055031.1 type IV pilus secretin PilQ family protein Machinery gene
  F8B64_RS03040 (F8B64_03040) - 605273..605959 (+) 687 WP_012055030.1 ComF family protein -
  F8B64_RS03045 (F8B64_03045) nfuA 606035..606631 (+) 597 WP_005649300.1 Fe-S biogenesis protein NfuA -
  F8B64_RS03050 (F8B64_03050) nudC 606698..607492 (+) 795 WP_012055029.1 NAD(+) diphosphatase -
  F8B64_RS03055 (F8B64_03055) - 607528..608118 (+) 591 WP_012055028.1 YjaG family protein -
  F8B64_RS03060 (F8B64_03060) - 608258..608530 (+) 273 WP_005630954.1 HU family DNA-binding protein -

Sequence

Protein


Download         Length: 445 a.a.        Molecular weight: 49172.49 Da        Isoelectric Point: 8.1446

>NTDB_id=390507 F8B64_RS03035 WP_012055031.1 603923..605260(+) (comE) [Haemophilus influenzae strain PittGG]
MKKYFLKCGYFLVCFCLPLIVFANPKTDNERFFIRLSQAPLAQTLEQLAFQQDVNLVMGERLEGNISLKLNNIDMPRLLK
IIAKSKHLTLNKDDGVYYLNCSQSGKGQVAGNLTTNEPHLVSHTVKLHFAKASELMKSLTTGSGSLLSPDGSITFDDRSN
LLVIQDEPRSVQNIKKLIAEMDKPIEQIAIEARIVTITDESLKELGVRWGIFNPTENARRVAGSLTGNSFENIADNLNVN
FATTTTPAGSIALQVAKINGRLLDLELSALERENNVEIIASPRLLTTNKKSASIKQGTEIPYIVSNTRNDTQSVEFREAV
LGLEVTPHISKDNNILLDLLVSQNSPGSRVAYGQNEVVSIDKQEINTQVFAKGGETIVLGGVFHDTITKSEDKVPLLGDI
PVIKRLFSKESERHQKRELVIFVTPHILKAGETLEALKQKSAGKK

Nucleotide


Download         Length: 1338 bp        

>NTDB_id=390507 F8B64_RS03035 WP_012055031.1 603923..605260(+) (comE) [Haemophilus influenzae strain PittGG]
ATGAAGAAATATTTTTTAAAGTGCGGTTATTTTTTAGTGTGTTTTTGTTTGCCATTAATCGTTTTTGCTAATCCTAAAAC
AGATAACGAACGTTTTTTTATTCGTTTATCGCAAGCACCTTTAGCTCAAACACTGGAGCAATTAGCTTTTCAACAAGATG
TGAATTTAGTGATGGGTGAGAGGTTAGAAGGCAATATTTCTTTGAAATTAAACAATATTGATATGCCACGTTTGCTAAAA
ATAATCGCAAAAAGTAAGCATCTTACTTTGAATAAAGATGATGGGGTTTATTATTTAAACTGCAGTCAATCTGGCAAAGG
TCAAGTTGCAGGAAATCTTACGACAAATGAACCGCACTTAGTCAGCCACACGGTAAAACTTCATTTTGCTAAAGCCTCTG
AATTAATGAAATCTTTAACAACAGGAAGTGGCTCTTTGCTTTCTCCCGATGGGAGCATTACCTTTGATGATCGCAGTAAT
TTGCTGGTTATTCAGGATGAACCTCGTTCTGTGCAAAATATCAAAAAACTGATTGCTGAAATGGATAAGCCTATTGAACA
GATCGCTATTGAAGCGCGAATTGTGACAATTACGGATGAGAGTTTGAAAGAACTTGGCGTTCGGTGGGGGATTTTTAATC
CAACTGAAAATGCAAGACGAGTTGCGGGCAGCCTTACAGGCAATAGCTTTGAAAATATTGCGGATAATCTTAATGTAAAT
TTTGCGACAACGACGACACCTGCTGGCTCTATAGCATTACAAGTTGCCAAAATTAATGGGCGATTGCTTGATTTAGAATT
GAGTGCGTTGGAGCGTGAAAATAATGTAGAAATTATTGCAAGTCCTCGCTTACTCACTACCAATAAGAAAAGTGCGAGCA
TTAAACAGGGGACAGAAATTCCTTACATCGTGAGTAATACTCGTAACGATACGCAATCTGTGGAATTTCGTGAGGCAGTA
CTTGGTTTGGAAGTGACGCCACATATTTCTAAAGATAACAATATCTTACTTGATTTATTGGTAAGTCAAAATTCCCCTGG
TTCTCGTGTCGCTTATGGACAAAATGAGGTGGTTTCTATTGATAAACAAGAAATTAATACTCAGGTTTTTGCCAAAGGTG
GGGAAACCATTGTGCTTGGCGGCGTATTTCACGATACAATCACGAAAAGCGAAGATAAAGTGCCATTGCTTGGCGATATA
CCCGTTATTAAACGATTATTTAGCAAAGAAAGTGAACGACATCAAAAACGTGAGCTAGTGATTTTCGTCACGCCACATAT
TTTAAAAGCAGGAGAAACGTTAGAGGCGTTGAAACAAAAAAGTGCGGGTAAAAAATAA

Domains

Predicted by InterproScan.

Bacterial type II/III secretion system short domain (Secretin_N)

(123-187)

Bacterial type II and III secretion system protein (Secretin)

(269-429)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comE Haemophilus influenzae 86-028NP

98.652

100

0.987
  comE Haemophilus influenzae Rd KW20

97.528

100

0.975
  comE Glaesserella parasuis strain SC1401

52.235

95.506

0.499
  pilQ Vibrio campbellii strain DS40M4

42.959

94.157

0.404
  pilQ Vibrio cholerae O1 biovar El Tor strain E7946

42.233

92.584

0.391
  pilQ Vibrio cholerae strain A1552

42.233

92.584

0.391

Multiple sequence alignment