Detailed information    

insolico Bioinformatically predicted

Overview

Name   vicR   Type   Regulator
Locus tag   FOB62_RS02130 Genome accession   NZ_CP044102
Coordinates   442324..443034 (-) Length   236 a.a.
NCBI ID   WP_150336165.1    Uniprot ID   -
Organism   Streptococcus dysgalactiae strain FDAARGOS_654     
Function   repress comCDE expression; repress comX expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 437324..448034
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  FOB62_RS02115 (FOB62_02115) rnc 438716..439408 (-) 693 WP_003057240.1 ribonuclease III -
  FOB62_RS02120 (FOB62_02120) vicX 440166..440975 (-) 810 WP_003057211.1 MBL fold metallo-hydrolase Regulator
  FOB62_RS02125 (FOB62_02125) vicK 440979..442331 (-) 1353 WP_014612101.1 cell wall metabolism sensor histidine kinase VicK Regulator
  FOB62_RS02130 (FOB62_02130) vicR 442324..443034 (-) 711 WP_150336165.1 response regulator YycF Regulator
  FOB62_RS02135 (FOB62_02135) - 443293..444087 (+) 795 WP_003057217.1 amino acid ABC transporter ATP-binding protein -
  FOB62_RS02140 (FOB62_02140) - 444087..444887 (+) 801 WP_003057243.1 transporter substrate-binding domain-containing protein -
  FOB62_RS02145 (FOB62_02145) - 444901..445602 (+) 702 WP_003057191.1 amino acid ABC transporter permease -
  FOB62_RS02150 (FOB62_02150) - 445617..446264 (+) 648 WP_003057245.1 amino acid ABC transporter permease -
  FOB62_RS02155 (FOB62_02155) - 446360..447355 (-) 996 WP_003057220.1 DUF3114 domain-containing protein -

Sequence

Protein


Download         Length: 236 a.a.        Molecular weight: 26986.92 Da        Isoelectric Point: 5.1118

>NTDB_id=387851 FOB62_RS02130 WP_150336165.1 442324..443034(-) (vicR) [Streptococcus dysgalactiae strain FDAARGOS_654]
MKKILIVDDEKPISDIIKFNLTKEGYGIVTAFDGREAVTIFEEEKPDLIILDLMLPELDGLEVAKEIRKTSHVPIIMLSA
KDSEFDKVIGLEIGADDYVTKPFSNRELLARVKAHLRRTETIETAVAEENASSGSQELTIGSLQILPDAFVAKKHGKEVE
LTHREFELLHHLANHMGQVMTREHLLETVWGYDYFGDVRTVDVTVRRLREKIEDTPSRPEYILTRRGIGYYMKSYD

Nucleotide


Download         Length: 711 bp        

>NTDB_id=387851 FOB62_RS02130 WP_150336165.1 442324..443034(-) (vicR) [Streptococcus dysgalactiae strain FDAARGOS_654]
ATGAAAAAAATACTGATTGTGGATGATGAAAAACCGATTTCTGACATTATTAAGTTTAATTTGACAAAAGAAGGTTATGG
CATTGTTACAGCTTTTGATGGACGCGAAGCGGTAACAATTTTTGAAGAAGAAAAGCCAGATTTAATTATTCTTGATTTGA
TGCTCCCTGAGTTGGACGGTCTTGAAGTAGCCAAGGAAATTCGTAAAACCAGTCATGTCCCGATTATTATGCTGTCGGCT
AAGGATAGTGAGTTTGACAAGGTCATTGGTCTTGAAATTGGGGCAGATGATTATGTTACCAAACCTTTTTCAAATCGTGA
ACTATTAGCGCGTGTCAAGGCTCATTTACGTCGAACAGAAACGATCGAAACAGCCGTAGCAGAGGAAAATGCTTCTTCAG
GTTCACAAGAGTTAACCATTGGTAGTTTACAAATTTTACCAGATGCTTTTGTGGCTAAAAAACATGGCAAAGAAGTGGAA
TTAACCCATCGTGAATTTGAATTATTACACCACCTGGCCAATCATATGGGTCAAGTGATGACACGAGAGCACTTGCTTGA
GACGGTTTGGGGCTATGATTACTTTGGCGATGTCCGTACTGTTGACGTGACGGTTCGTCGTCTGCGTGAAAAAATTGAAG
ACACACCAAGCCGTCCCGAATATATTTTAACGAGACGCGGTATTGGGTACTACATGAAATCTTATGACTAG

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(4-113)

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(156-231)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vicR Streptococcus mutans UA159

89.831

100

0.898
  micA Streptococcus pneumoniae Cp1015

79.06

99.153

0.784
  covR Lactococcus lactis subsp. lactis strain DGCC12653

44.828

98.305

0.441
  covR Streptococcus salivarius strain HSISS4

44.397

98.305

0.436
  scnR Streptococcus mutans UA159

36.91

98.729

0.364

Multiple sequence alignment