Detailed information NTG0387850

Bioinformatically predicted

Overview

• Name: vicK
• Type: Regulator
• Locus tag: FOB62_RS02125
• Genome accession: NZ_CP044102
• Coordinates: 440979..442331 (-)
• Length: 450 a.a.
• NCBI ID: WP_014612101.1
• Uniprot ID: A0AB38Y2E7
• Organism: Streptococcus dysgalactiae strain FDAARGOS_654
• Function: repress comCDE expression; repress comX expression (predicted from homology) Competence regulation

Genomic Context

Location: 435979..447331

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
FOB62_RS02115 (FOB62_02115)	rnc	438716..439408 (-)	693	WP_003057240.1	ribonuclease III	-
FOB62_RS02120 (FOB62_02120)	vicX	440166..440975 (-)	810	WP_003057211.1	MBL fold metallo-hydrolase	Regulator
FOB62_RS02125 (FOB62_02125)	vicK	440979..442331 (-)	1353	WP_014612101.1	cell wall metabolism sensor histidine kinase VicK	Regulator
FOB62_RS02130 (FOB62_02130)	vicR	442324..443034 (-)	711	WP_150336165.1	response regulator YycF	Regulator
FOB62_RS02135 (FOB62_02135)	-	443293..444087 (+)	795	WP_003057217.1	amino acid ABC transporter ATP-binding protein	-
FOB62_RS02140 (FOB62_02140)	-	444087..444887 (+)	801	WP_003057243.1	transporter substrate-binding domain-containing protein	-
FOB62_RS02145 (FOB62_02145)	-	444901..445602 (+)	702	WP_003057191.1	amino acid ABC transporter permease	-
FOB62_RS02150 (FOB62_02150)	-	445617..446264 (+)	648	WP_003057245.1	amino acid ABC transporter permease	-

Sequence

Protein

• Length: 450 a.a.
• Molecular weight: 51476.06 Da
• Isoelectric Point: 5.7411

>NTDB_id=387850 FOB62_RS02125 WP_014612101.1 440979..442331(-) (vicK) [Streptococcus dysgalactiae strain FDAARGOS_654]
MTRDIIGNLSAFELAILLLLVFVAFYFIHLAVRDYRNARIIRMMSHKIRDLINGRYTDMINEKADIELMELADQLNDLSD
VFRLTHENLAQEKNRLASILAYMSDGVLATDRSGKIIMINETARKQLNLTKEKALEKNITDLLEGDTPYTYRELVSKTPV
VTVNSRNDMGEFVTLRLRFALNRRESGFISGLVVVLHDTTEQEKEERERRLFVSNVSHELRTPLTSVKSYLEALDEGAIK
EDIAPSFIKVSLDETNRMMRMISDLLNLSRIDNQVTQLSVEMTNFTAFMTSILNRFDLVKNQHTGTGKVYEIVRDYPITS
VWLEIDNDKMTQVIENILNNAIKYSPDGGKITVRMKTTDTQLIISISDQGLGIPKKDLPLIFDRFYRVDKARSRAQGGTG
LGLAIAKEIIKQHHGFIWAKSDYGKGSTFTIVLPYEKDAAIYEEWEDDID

Nucleotide

• Length: 1353 bp

>NTDB_id=387850 FOB62_RS02125 WP_014612101.1 440979..442331(-) (vicK) [Streptococcus dysgalactiae strain FDAARGOS_654]
ATGACTAGAGATATCATTGGAAACTTATCCGCTTTTGAATTAGCGATTCTCTTATTACTTGTTTTTGTTGCCTTTTATTT
TATTCACTTAGCGGTGCGTGATTACCGAAATGCCCGTATTATTCGAATGATGAGCCATAAAATCAGAGACCTGATTAATG
GCCGTTATACCGACATGATTAACGAAAAGGCTGACATTGAATTGATGGAACTGGCAGATCAGTTAAACGATCTCTCAGAC
GTGTTTCGCTTAACCCATGAGAATCTTGCCCAGGAAAAAAATCGCTTGGCCAGCATTCTGGCCTATATGTCAGATGGCGT
ACTTGCCACAGACCGGTCTGGTAAAATCATCATGATTAACGAGACAGCTCGCAAGCAGCTCAATCTGACCAAGGAGAAGG
CCCTTGAAAAGAACATTACCGATTTGTTGGAGGGAGATACCCCCTATACCTATCGTGAATTGGTTTCCAAAACGCCTGTT
GTGACGGTCAATAGTCGCAATGACATGGGTGAGTTTGTTACATTACGTTTACGCTTCGCCTTAAACAGACGAGAAAGTGG
TTTTATTTCTGGTTTGGTTGTGGTGCTCCATGACACTACAGAACAGGAAAAGGAAGAACGTGAACGCCGGTTGTTTGTTT
CTAATGTGAGTCATGAGTTGAGAACACCTTTGACATCGGTGAAATCCTACTTGGAGGCTCTTGACGAAGGTGCCATCAAG
GAAGATATTGCTCCAAGTTTCATAAAAGTTTCTCTTGATGAAACCAATCGGATGATGCGTATGATTTCCGATCTTTTAAA
CTTGTCTCGCATTGATAACCAAGTAACTCAGTTATCTGTCGAGATGACCAATTTTACAGCTTTTATGACATCTATCCTGA
ACCGATTTGACCTAGTTAAAAACCAGCACACCGGTACTGGCAAGGTTTATGAAATTGTGAGAGACTATCCGATTACCTCT
GTTTGGCTGGAAATTGATAATGATAAGATGACGCAGGTTATTGAAAATATCCTAAACAACGCGATTAAATACTCTCCTGA
TGGTGGGAAAATCACTGTTCGCATGAAAACAACCGACACGCAATTGATTATTTCCATCTCAGACCAAGGCTTAGGCATTC
CGAAGAAGGATCTGCCCCTTATTTTTGACCGTTTTTACCGTGTGGACAAGGCAAGAAGCCGTGCTCAAGGTGGAACTGGT
CTAGGGCTTGCCATTGCCAAAGAAATTATTAAGCAGCATCACGGGTTTATTTGGGCGAAGAGTGATTATGGCAAAGGATC
AACCTTTACCATCGTCTTGCCATATGAAAAAGATGCTGCCATTTACGAAGAGTGGGAGGATGACATAGATTAA

Domains

Predicted by InterproScan.

• PAS fold (PAS) (95-165)

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (326-436)

• His Kinase A (phospho-acceptor) domain (HisKA) (209-273)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vicK	Streptococcus mutans UA159	73.188	92	0.673
micB	Streptococcus pneumoniae Cp1015	66.588	94.444	0.629