Detailed information NTG0385776

Bioinformatically predicted

Overview

• Name: comGF
• Type: Machinery gene
• Locus tag: HG697_RS01065
• Genome accession: NZ_CP051623
• Coordinates: 167322..167762 (+)
• Length: 146 a.a.
• NCBI ID: WP_003058520.1
• Uniprot ID: A0ABU0A7B0
• Organism: Streptococcus dysgalactiae subsp. equisimilis strain TPCH-A19
• Function: dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 162322..172762

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
HG697_RS01025 (HG697_01030)	-	163481..163909 (+)	429	WP_003058584.1	DUF1366 domain-containing protein	-
HG697_RS01030 (HG697_01035)	-	163875..164102 (+)	228	WP_037588167.1	hypothetical protein	-
HG697_RS01035 (HG697_01040)	-	164110..164577 (+)	468	WP_003058491.1	phage holin family protein	-
HG697_RS01040 (HG697_01045)	-	164570..164905 (+)	336	WP_003058565.1	phage holin	-
HG697_RS01045 (HG697_01050)	-	164907..166352 (+)	1446	WP_170078900.1	peptidoglycan amidohydrolase family protein	-
HG697_RS01050 (HG697_01055)	prx	166490..166681 (+)	192	WP_003058494.1	hypothetical protein	Regulator
HG697_RS01055 (HG697_01060)	comGD	166696..167088 (+)	393	WP_003058533.1	competence type IV pilus minor pilin ComGD	Machinery gene
HG697_RS01060 (HG697_01065)	comGE	167096..167341 (+)	246	WP_003058569.1	competence type IV pilus minor pilin ComGE	Machinery gene
HG697_RS01065 (HG697_01070)	comGF	167322..167762 (+)	441	WP_003058520.1	competence type IV pilus minor pilin ComGF	Machinery gene
HG697_RS01070 (HG697_01075)	comGG	167785..168114 (+)	330	WP_003058539.1	competence type IV pilus minor pilin ComGG	-
HG697_RS01075 (HG697_01080)	comGH	168177..169130 (+)	954	WP_003060701.1	class I SAM-dependent methyltransferase	Machinery gene
HG697_RS01080 (HG697_01085)	-	169189..170385 (+)	1197	WP_015057203.1	acetate kinase	-
HG697_RS01085 (HG697_01090)	-	170691..170897 (+)	207	WP_003058508.1	helix-turn-helix transcriptional regulator	-
HG697_RS01090 (HG697_01095)	-	171000..171680 (+)	681	WP_012766451.1	type II CAAX endopeptidase family protein	-
HG697_RS01095 (HG697_01100)	-	171698..172135 (+)	438	WP_012766452.1	hypothetical protein	-

Sequence

Protein

• Length: 146 a.a.
• Molecular weight: 16968.61 Da
• Isoelectric Point: 10.7829

>NTDB_id=385776 HG697_RS01065 WP_003058520.1 167322..167762(+) (comGF) [Streptococcus dysgalactiae subsp. equisimilis strain TPCH-A19]
MKKRTGRVQAFTFLEALIALLVISGSLLVYQGLTKTLLSHSRYLTKNDQDHWLLFSQQLREELSGARFHKVENNKLYIEK
GKKKLVLGQFKSHDFRKSAGNGQGYQPMLFGLSHSHIQAEQSRIRITLHWKSGLKRTFYYAFQDQP

Nucleotide

• Length: 441 bp

>NTDB_id=385776 HG697_RS01065 WP_003058520.1 167322..167762(+) (comGF) [Streptococcus dysgalactiae subsp. equisimilis strain TPCH-A19]
TTGAAAAAAAGGACAGGTAGGGTCCAAGCATTTACTTTTTTAGAGGCTTTAATTGCCTTACTGGTGATATCAGGTTCTCT
TCTAGTGTATCAAGGATTGACCAAAACACTCCTTAGCCACAGTCGCTACCTTACCAAAAATGATCAAGACCATTGGCTTT
TGTTCTCCCAGCAGTTACGAGAAGAGTTAAGTGGAGCGCGATTTCACAAAGTAGAGAACAATAAATTATATATCGAAAAA
GGCAAGAAAAAACTAGTTTTAGGACAATTTAAAAGCCATGACTTTCGAAAATCGGCAGGCAATGGACAAGGTTATCAACC
CATGCTGTTTGGCCTGTCTCATAGTCATATACAAGCAGAGCAGTCTCGTATTCGTATTACCCTTCACTGGAAAAGTGGAC
TAAAAAGGACCTTCTACTATGCGTTTCAAGACCAACCTTAA

Domains

Predicted by InterProScan.

• Putative Competence protein ComGF (ComGF) (40-135)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comGF	Streptococcus mutans UA159	48.201	95.205	0.459
comGF	Streptococcus mutans UA140	47.482	95.205	0.452
comGF	Lactococcus lactis subsp. cremoris KW2	45.652	94.521	0.432
comGF/cglF	Streptococcus pneumoniae D39	43.066	93.836	0.404
comGF/cglF	Streptococcus mitis NCTC 12261	43.066	93.836	0.404
comGF/cglF	Streptococcus pneumoniae TIGR4	43.066	93.836	0.404
comGF/cglF	Streptococcus pneumoniae R6	43.066	93.836	0.404
comGF/cglF	Streptococcus mitis SK321	43.066	93.836	0.404
comGF/cglF	Streptococcus pneumoniae Rx1	43.066	93.836	0.404