Detailed information
Bioinformatically predicted
Overview
| Name | prx | Type | Regulator |
| Locus tag | MGAS2221_RS05070 | Genome accession | NZ_CP043530 |
| Coordinates | 1007315..1007503 (-) | Length | 62 a.a. |
| NCBI ID | WP_011285559.1 | Uniprot ID | - |
| Organism | Streptococcus pyogenes strain MGAS2221 | ||
| Function | Inhibit ComR activation (predicted from homology) Competence regulation |
||
Genomic Context
Location: 1002315..1012503
| Locus tag | Gene name | Coordinates (strand) | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| MGAS2221_RS05045 (MGAS2221_1003) | - | 1004119..1004490 (+) | 372 | WP_010922377.1 | GntR family transcriptional regulator | - |
| MGAS2221_RS05050 (MGAS2221_1004) | - | 1004490..1005188 (+) | 699 | WP_002984437.1 | ABC transporter ATP-binding protein | - |
| MGAS2221_RS05055 (MGAS2221_1005) | - | 1005198..1005983 (+) | 786 | WP_010922378.1 | hypothetical protein | - |
| MGAS2221_RS05060 (MGAS2221_1006) | - | 1006110..1006724 (-) | 615 | WP_011285558.1 | TVP38/TMEM64 family protein | - |
| MGAS2221_RS05070 (MGAS2221_1008) | prx | 1007315..1007503 (-) | 189 | WP_011285559.1 | hypothetical protein | Regulator |
| MGAS2221_RS05075 (MGAS2221_1009) | speA | 1007723..1008478 (+) | 756 | WP_011285560.1 | streptococcal pyrogenic exotoxin SpeA | - |
| MGAS2221_RS05080 (MGAS2221_1010) | - | 1008600..1009259 (-) | 660 | WP_009880240.1 | hypothetical protein | - |
| MGAS2221_RS05085 (MGAS2221_1011) | - | 1009259..1009480 (-) | 222 | WP_009880241.1 | hypothetical protein | - |
| MGAS2221_RS05090 (MGAS2221_1012) | - | 1009490..1010263 (-) | 774 | WP_011054795.1 | hypothetical protein | - |
| MGAS2221_RS05095 (MGAS2221_1013) | - | 1010274..1010876 (-) | 603 | WP_011054796.1 | hypothetical protein | - |
| MGAS2221_RS05100 (MGAS2221_1014) | - | 1010888..1011652 (-) | 765 | WP_011285561.1 | CHAP domain-containing protein | - |
| MGAS2221_RS05105 (MGAS2221_1015) | - | 1011654..1011986 (-) | 333 | WP_011285562.1 | phage holin | - |
| MGAS2221_RS05110 (MGAS2221_1016) | - | 1011986..1012309 (-) | 324 | WP_015055952.1 | hypothetical protein | - |
| MGAS2221_RS09420 (MGAS2221_1017) | - | 1012323..1012445 (-) | 123 | WP_015055953.1 | hypothetical protein | - |
Sequence
Protein
Download Length: 62 a.a. Molecular weight: 7290.41 Da Isoelectric Point: 4.3313
>NTDB_id=384843 MGAS2221_RS05070 WP_011285559.1 1007315..1007503(-) (prx) [Streptococcus pyogenes strain MGAS2221]
MLYIDEFKEAIDKGYILGDTVAIVRKNGKIFDYVLPHEKVRDDEVVTVERVEEVMVELDYIK
MLYIDEFKEAIDKGYILGDTVAIVRKNGKIFDYVLPHEKVRDDEVVTVERVEEVMVELDYIK
Nucleotide
Download Length: 189 bp
>NTDB_id=384843 MGAS2221_RS05070 WP_011285559.1 1007315..1007503(-) (prx) [Streptococcus pyogenes strain MGAS2221]
ATGTTATATATAGATGAGTTTAAAGAAGCGATTGATAAGGGGTATATTTTAGGTGACACAGTAGCGATAGTGCGTAAAAA
CGGAAAGATATTTGATTATGTGTTACCACACGAAAAAGTGAGAGATGATGAAGTTGTGACGGTAGAGAGAGTGGAAGAAG
TGATGGTGGAATTAGACTATATCAAATGA
ATGTTATATATAGATGAGTTTAAAGAAGCGATTGATAAGGGGTATATTTTAGGTGACACAGTAGCGATAGTGCGTAAAAA
CGGAAAGATATTTGATTATGTGTTACCACACGAAAAAGTGAGAGATGATGAAGTTGTGACGGTAGAGAGAGTGGAAGAAG
TGATGGTGGAATTAGACTATATCAAATGA
Domains
No domain identified.
3D structure
| Source | ID | Structure |
|---|
Similar proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|---|---|---|---|
| prx | Streptococcus pyogenes MGAS315 |
100 |
95.161 |
0.952 |
| prx | Streptococcus pyogenes MGAS315 |
79.032 |
100 |
0.79 |
| prx | Streptococcus pyogenes MGAS8232 |
76.271 |
95.161 |
0.726 |
| prx | Streptococcus pyogenes MGAS315 |
76.271 |
95.161 |
0.726 |
| prx | Streptococcus pyogenes MGAS315 |
74.576 |
95.161 |
0.71 |
| prx | Streptococcus pyogenes MGAS315 |
69.492 |
95.161 |
0.661 |
| prx | Streptococcus pyogenes MGAS315 |
82.927 |
66.129 |
0.548 |