Detailed information NTG0383587

Bioinformatically predicted

Overview

• Name: clpP
• Type: Regulator
• Locus tag: FY406_RS06155
• Genome accession: NZ_CP043405
• Coordinates: 1232624..1233214 (+)
• Length: 196 a.a.
• NCBI ID: WP_003087212.1
• Uniprot ID: A0A7X9LCB7
• Organism: Streptococcus ratti strain ATCC 31377
• Function: degradation of ComX; require for competence development (at the early growth phase); repress competence development (at the mid-logarithmic growth phase) (predicted from homology) Competence regulation

Genomic Context

Location: 1227624..1238214

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
FY406_RS06135 (FY406_06135)	-	1228361..1229455 (+)	1095	WP_003087204.1	cystathionine gamma-synthase	-
FY406_RS06140 (FY406_06140)	-	1229465..1230625 (+)	1161	WP_003087206.1	MalY/PatB family protein	-
FY406_RS06145 (FY406_06145)	-	1230995..1231189 (+)	195	WP_003087208.1	hypothetical protein	-
FY406_RS06150 (FY406_06150)	upp	1231809..1232438 (+)	630	WP_003087210.1	uracil phosphoribosyltransferase	-
FY406_RS06155 (FY406_06155)	clpP	1232624..1233214 (+)	591	WP_003087212.1	ATP-dependent Clp protease proteolytic subunit ClpP	Regulator
FY406_RS06160 (FY406_06160)	-	1233360..1233800 (+)	441	WP_003087214.1	YlbF family regulator	-
FY406_RS06165 (FY406_06165)	-	1233806..1234054 (+)	249	WP_003087216.1	DUF2129 domain-containing protein	-
FY406_RS06170 (FY406_06170)	-	1234156..1235331 (+)	1176	WP_003087218.1	ABC transporter substrate-binding protein	-
FY406_RS06175 (FY406_06175)	-	1235415..1236284 (+)	870	WP_003087220.1	branched-chain amino acid ABC transporter permease	-
FY406_RS06180 (FY406_06180)	-	1236288..1237244 (+)	957	WP_003087222.1	branched-chain amino acid ABC transporter permease	-
FY406_RS06185 (FY406_06185)	-	1237244..1238008 (+)	765	WP_003087227.1	ABC transporter ATP-binding protein	-

Sequence

Protein

• Length: 196 a.a.
• Molecular weight: 21714.00 Da
• Isoelectric Point: 5.3292

>NTDB_id=383587 FY406_RS06155 WP_003087212.1 1232624..1233214(+) (clpP) [Streptococcus ratti strain ATCC 31377]
MIPVVIEQTSRGERSYDIYSRLLKDRIIMLTGPVEDNMANSIIAQLLFLDAQDNTKDIYLYINTPGGSVSAGLAIVDTMN
FIKSDVQTIVMGIAASMGTIIASSGTKGKRFMLPNAEYLIHQPMGGTGGGTQQTDMAIAAEQLLKTRKKLEKILSDNSGK
TIKQVHKDAERDYWMDAKETLKYGFIDEIMENNELK

Nucleotide

• Length: 591 bp

>NTDB_id=383587 FY406_RS06155 WP_003087212.1 1232624..1233214(+) (clpP) [Streptococcus ratti strain ATCC 31377]
ATGATTCCTGTAGTTATTGAACAAACAAGCCGTGGAGAACGTTCTTATGATATCTATTCACGTCTTTTAAAAGATCGTAT
TATTATGCTGACTGGTCCTGTCGAAGACAATATGGCAAATTCTATTATTGCTCAGCTTCTTTTCCTGGATGCTCAGGACA
ACACAAAAGATATTTATCTTTATATTAATACACCAGGCGGCTCTGTTTCAGCAGGTTTGGCAATCGTTGATACTATGAAT
TTCATCAAATCAGACGTTCAGACTATTGTTATGGGAATAGCAGCGTCGATGGGAACAATCATTGCATCCAGCGGTACCAA
GGGCAAACGGTTCATGCTGCCAAATGCTGAGTACCTGATTCACCAGCCAATGGGCGGAACAGGTGGCGGTACACAGCAGA
CAGATATGGCTATTGCAGCTGAACAGCTCTTAAAAACGCGTAAGAAGCTGGAAAAAATTCTGTCAGATAATTCTGGCAAG
ACAATTAAGCAGGTTCACAAAGACGCTGAACGCGATTACTGGATGGATGCCAAAGAAACCCTTAAATATGGCTTCATCGA
TGAAATCATGGAAAATAATGAACTGAAGTGA

Domains

Predicted by InterproScan.

• Clp protease (CLP_protease) (11-192)

3D structure

• AlphaFold DB: A0A7X9LCB7

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpP	Streptococcus mutans UA159	97.959	100	0.98
clpP	Streptococcus pyogenes MGAS315	91.837	100	0.918
clpP	Streptococcus pyogenes JRS4	91.837	100	0.918
clpP	Streptococcus thermophilus LMD-9	89.796	100	0.898
clpP	Streptococcus thermophilus LMG 18311	89.796	100	0.898
clpP	Lactococcus lactis subsp. lactis strain DGCC12653	88.776	100	0.888
clpP	Lactococcus lactis subsp. cremoris KW2	88.265	100	0.883
clpP	Streptococcus pneumoniae D39	87.179	99.49	0.867
clpP	Streptococcus pneumoniae TIGR4	87.179	99.49	0.867
clpP	Streptococcus pneumoniae R6	87.179	99.49	0.867
clpP	Streptococcus pneumoniae Rx1	87.179	99.49	0.867
clpP	Bacillus subtilis subsp. subtilis str. 168	55.612	100	0.556
clpP	Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819	55.959	98.469	0.551