Detailed information    

insolico Bioinformatically predicted

Overview


Name   clpP   Type   Regulator
Locus tag   HEP85_RS03750 Genome accession   NZ_CP050975
Coordinates   955018..955620 (+) Length   200 a.a.
NCBI ID   WP_168526174.1    Uniprot ID   A0ABW3XNW2
Organism   Streptomyces sp. RPA4-2     
Function   degradation of ComK; degradation of DegU (predicted from homology)   
Competence regulation

Genomic Context


Location: 950018..960620
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  HEP85_RS03725 (HEP85_03895) - 950686..951702 (+) 1017 WP_369658105.1 zinc-binding alcohol dehydrogenase family protein -
  HEP85_RS03730 (HEP85_03900) - 951786..952181 (-) 396 WP_168526169.1 nitroreductase/quinone reductase family protein -
  HEP85_RS03735 (HEP85_03905) - 952342..952824 (-) 483 WP_365219475.1 VOC family protein -
  HEP85_RS03740 (HEP85_03910) - 953067..954293 (+) 1227 WP_168526170.1 epoxide hydrolase family protein -
  HEP85_RS03745 (HEP85_03915) clpP 954363..955016 (+) 654 WP_168526172.1 ATP-dependent Clp protease proteolytic subunit Regulator
  HEP85_RS03750 (HEP85_03920) clpP 955018..955620 (+) 603 WP_168526174.1 ClpP family protease Regulator
  HEP85_RS03755 (HEP85_03925) - 955650..956135 (-) 486 WP_168526176.1 RodZ family helix-turn-helix domain-containing protein -
  HEP85_RS03760 (HEP85_03930) - 956397..957176 (+) 780 WP_168526178.1 class I SAM-dependent methyltransferase -
  HEP85_RS03765 (HEP85_03935) - 957187..957381 (-) 195 Protein_750 DUF664 domain-containing protein -
  HEP85_RS03770 (HEP85_03940) - 957611..959056 (-) 1446 WP_369657575.1 diacylglycerol kinase family protein -
  HEP85_RS03775 (HEP85_03945) - 959170..959613 (-) 444 WP_168526182.1 response regulator -

Sequence


Protein


Download         Length: 200 a.a.        Molecular weight: 21655.66 Da        Isoelectric Point: 5.2728

>NTDB_id=382307 HEP85_RS03750 WP_168526174.1 955018..955620(+) (clpP) [Streptomyces sp. RPA4-2]
MGTYTIPNVVERTPQGERSYDVFSRLLSERIIFLGTEIDDGVANVVIAQLLHLESSSPESEIALYINSPGGSVTSLMAIY
DTMTFVQAPISTFCVGQAASTAAVLLAGGDPGRRFVLEHARVLLGQPASGGRQGTVSDLALQAKEMLRIRSQVEEVLSRH
THHDVTVLRADMDRDKVLTAREAVAYGMADEVLSRRLATV

Nucleotide


Download         Length: 603 bp        

>NTDB_id=382307 HEP85_RS03750 WP_168526174.1 955018..955620(+) (clpP) [Streptomyces sp. RPA4-2]
ATGGGTACGTACACGATTCCGAACGTCGTCGAGCGCACCCCGCAGGGCGAGCGGTCCTACGACGTCTTCAGCCGGCTGCT
CTCGGAGCGGATCATCTTCCTCGGCACCGAGATCGACGACGGGGTCGCCAATGTCGTCATCGCCCAGCTCCTCCATCTGG
AGTCGTCGAGCCCGGAGAGCGAGATCGCCCTCTACATCAACTCGCCGGGTGGTTCGGTCACTTCGCTCATGGCGATCTAC
GACACGATGACATTCGTCCAGGCGCCCATCTCGACCTTCTGCGTCGGGCAGGCGGCGTCGACGGCGGCGGTGCTGCTGGC
CGGAGGCGATCCGGGGCGGCGGTTCGTACTGGAGCACGCGCGGGTGCTGCTCGGCCAGCCCGCGAGCGGTGGCCGCCAGG
GCACCGTCTCCGATCTCGCCCTCCAGGCCAAGGAGATGCTCCGGATCCGCTCCCAGGTCGAGGAGGTCCTGTCCCGGCAC
ACGCACCACGACGTCACGGTGCTGCGCGCGGACATGGACCGCGACAAGGTCCTCACGGCGCGGGAGGCGGTGGCGTACGG
AATGGCCGACGAGGTGCTGAGCCGACGGCTCGCGACGGTCTGA

Domains


Predicted by InterProScan.

(15-195)


Secondary structure


Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure


Source ID Structure

Transmembrane helices


Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.



Visualization of predicted probability:


Similar proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  clpP Bacillus subtilis subsp. subtilis str. 168

48.677

94.5

0.46

  clpP Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819

45.789

95

0.435

  clpP Streptococcus mutans UA159

41.27

94.5

0.39

  clpP Streptococcus pneumoniae R6

40.104

96

0.385

  clpP Streptococcus pneumoniae Rx1

40.104

96

0.385

  clpP Streptococcus pneumoniae D39

40.104

96

0.385

  clpP Streptococcus pneumoniae TIGR4

40.104

96

0.385

  clpP Streptococcus pyogenes JRS4

40.104

96

0.385

  clpP Streptococcus pyogenes MGAS315

40.104

96

0.385

  clpP Lactococcus lactis subsp. cremoris KW2

39.175

97

0.38

  clpP Streptococcus thermophilus LMG 18311

38.542

96

0.37

  clpP Streptococcus thermophilus LMD-9

38.542

96

0.37

  clpP Lactococcus lactis subsp. lactis strain DGCC12653

37.629

97

0.365