Detailed information NTG0375333

Bioinformatically predicted

Overview

• Name: clpP
• Type: Regulator
• Locus tag: G9W36_RS05620
• Genome accession: NZ_CP049839
• Coordinates: 1180899..1181522 (+)
• Length: 207 a.a.
• NCBI ID: WP_000122253.1
• Uniprot ID: A0A370V1H3
• Organism: Escherichia coli strain UPEC-455U/190220
• Function: degradation of ComK; degradation of DegU (predicted from homology) Competence regulation

Genomic Context

Location: 1175899..1186522

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
G9W36_RS05600 (G9W36_05600)	ampG	1176292..1177767 (-)	1476	WP_000098442.1	muropeptide MFS transporter AmpG	-
G9W36_RS05605 (G9W36_05605)	yajG	1177811..1178389 (-)	579	WP_001295326.1	lipoprotein	-
G9W36_RS05610 (G9W36_05610)	bolA	1178694..1179011 (+)	318	WP_000973448.1	transcriptional regulator BolA	-
G9W36_RS05615 (G9W36_05615)	tig	1179355..1180653 (+)	1299	WP_001538385.1	trigger factor	-
G9W36_RS05620 (G9W36_05620)	clpP	1180899..1181522 (+)	624	WP_000122253.1	ATP-dependent Clp endopeptidase proteolytic subunit ClpP	Regulator
G9W36_RS05625 (G9W36_05625)	clpX	1181648..1182922 (+)	1275	WP_000130305.1	ATP-dependent protease ATP-binding subunit ClpX	Regulator
G9W36_RS05630 (G9W36_05630)	lon	1183110..1185464 (+)	2355	WP_001295325.1	endopeptidase La	-
G9W36_RS05635 (G9W36_05635)	hupB	1185673..1185945 (+)	273	WP_001043542.1	nucleoid-associated protein HU-beta	-

Sequence

Protein

• Length: 207 a.a.
• Molecular weight: 23186.65 Da
• Isoelectric Point: 5.6032

>NTDB_id=375333 G9W36_RS05620 WP_000122253.1 1180899..1181522(+) (clpP) [Escherichia coli strain UPEC-455U/190220]
MSYSGERDNFAPHMALVPMVIEQTSRGERSFDIYSRLLKERVIFLTGQVEDHMANLIVAQMLFLEAENPEKDIYLYINSP
GGVITAGMSIYDTMQFIKPDVSTICMGQAASMGAFLLTAGAKGKRFCLPNSRVMIHQPLGGYQGQATDIEIHAREILKVK
GRMNELMALHTGQSLEQIERDTERDRFLSAPEAVEYGLVDSILTHRN

Nucleotide

• Length: 624 bp

>NTDB_id=375333 G9W36_RS05620 WP_000122253.1 1180899..1181522(+) (clpP) [Escherichia coli strain UPEC-455U/190220]
ATGTCATACAGCGGCGAACGAGATAACTTTGCACCCCATATGGCGCTGGTGCCGATGGTCATTGAACAGACCTCACGAGG
TGAGCGCTCTTTTGATATCTATTCTCGTCTACTTAAGGAACGCGTCATTTTTCTGACTGGCCAGGTTGAAGATCACATGG
CTAACCTGATTGTGGCGCAGATGCTGTTCCTGGAAGCAGAAAACCCAGAAAAAGATATCTATCTGTACATTAACTCTCCA
GGCGGGGTGATTACTGCCGGGATGTCTATCTATGACACCATGCAGTTTATCAAGCCTGATGTCAGCACCATCTGTATGGG
CCAGGCGGCCTCGATGGGTGCTTTCTTGCTGACTGCAGGGGCAAAAGGTAAACGTTTCTGCCTGCCGAATTCGCGCGTGA
TGATTCACCAGCCGTTGGGCGGCTACCAGGGCCAAGCGACCGATATCGAAATTCATGCCCGTGAAATTCTGAAAGTTAAA
GGGCGCATGAATGAACTTATGGCGCTTCATACGGGTCAATCATTAGAACAGATTGAACGTGATACCGAGCGCGATCGCTT
CCTTTCTGCCCCTGAAGCGGTGGAATACGGTCTGGTCGATTCGATTCTGACCCATCGTAATTGA

Domains

Predicted by InterProScan.

• Clp protease (CLP_protease) (26-205)

3D structure

• AlphaFold DB: A0A370V1H3

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpP	Bacillus subtilis subsp. subtilis str. 168	69.792	92.754	0.647
clpP	Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819	68.617	90.821	0.623
clpP	Lactococcus lactis subsp. cremoris KW2	56.701	93.72	0.531
clpP	Streptococcus pneumoniae R6	55.155	93.72	0.517
clpP	Streptococcus pneumoniae TIGR4	55.155	93.72	0.517
clpP	Lactococcus lactis subsp. lactis strain DGCC12653	55.155	93.72	0.517
clpP	Streptococcus pneumoniae Rx1	55.155	93.72	0.517
clpP	Streptococcus pneumoniae D39	55.155	93.72	0.517
clpP	Streptococcus thermophilus LMD-9	54.922	93.237	0.512
clpP	Streptococcus thermophilus LMG 18311	54.922	93.237	0.512
clpP	Streptococcus pyogenes JRS4	55.263	91.787	0.507
clpP	Streptococcus pyogenes MGAS315	55.263	91.787	0.507
clpP	Streptococcus mutans UA159	53.886	93.237	0.502