Detailed information    

insolico Bioinformatically predicted

Overview

Name   comEA/celA/cilE   Type   Machinery gene
Locus tag   FPL13_RS04055 Genome accession   NZ_CP041968
Coordinates   825677..826381 (-) Length   234 a.a.
NCBI ID   WP_049512789.1    Uniprot ID   A0A7L8W7D7
Organism   Streptococcus sp. KS 6     
Function   dsDNA binding to the cell surface (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 820677..831381
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  FPL13_RS04035 (FPL13_04085) - 821383..822320 (+) 938 Protein_795 IS30 family transposase -
  FPL13_RS04040 - 822398..822556 (+) 159 WP_185952229.1 hypothetical protein -
  FPL13_RS04045 (FPL13_04090) - 822699..823385 (-) 687 WP_225620253.1 DUF805 domain-containing protein -
  FPL13_RS04050 (FPL13_04095) - 823466..825693 (-) 2228 Protein_798 DNA internalization-related competence protein ComEC/Rec2 -
  FPL13_RS04055 (FPL13_04100) comEA/celA/cilE 825677..826381 (-) 705 WP_049512789.1 helix-hairpin-helix domain-containing protein Machinery gene
  FPL13_RS04060 (FPL13_04105) smpB 826563..827030 (-) 468 WP_049512786.1 SsrA-binding protein SmpB -
  FPL13_RS04065 (FPL13_04110) rnr 826993..829326 (-) 2334 WP_192208661.1 ribonuclease R -
  FPL13_RS04070 (FPL13_04115) secG 829418..829651 (-) 234 WP_003024744.1 preprotein translocase subunit SecG -
  FPL13_RS04075 (FPL13_04120) rpmG 829691..829840 (-) 150 WP_003024746.1 50S ribosomal protein L33 -
  FPL13_RS04080 (FPL13_04125) - 829824..831029 (-) 1206 WP_080984151.1 multidrug efflux MFS transporter -

Sequence

Protein


Download         Length: 234 a.a.        Molecular weight: 24950.94 Da        Isoelectric Point: 4.8720

>NTDB_id=375007 FPL13_RS04055 WP_049512789.1 825677..826381(-) (comEA/celA/cilE) [Streptococcus sp. KS 6]
MLETIIEKMKEYKILIGLSLIGLIIAGFFMINGQSSRQSNVAELAQETVASSKTESEEISTGTKKNSQKEKAETQTSSSE
ESEFLTVDVKGAVKNPGIYQLKKTSRINDAIQKAGGLTTDADSKSINLAQKLTDEAVVYVATVGENATSVASGTGQSSTL
GTSEVASQKGNKVNLNTADLSELQTISGIGQKRAQDILDYREANGKFNSVDDLKNVSGVGAKTLEKLKEYVTVD

Nucleotide


Download         Length: 705 bp        

>NTDB_id=375007 FPL13_RS04055 WP_049512789.1 825677..826381(-) (comEA/celA/cilE) [Streptococcus sp. KS 6]
ATGTTAGAGACAATCATTGAAAAGATGAAAGAGTATAAAATTTTGATTGGTTTAAGTTTGATTGGTTTGATAATAGCAGG
ATTTTTTATGATAAATGGTCAATCTAGTAGACAATCAAATGTAGCAGAGCTCGCACAGGAAACAGTTGCTAGTTCTAAAA
CAGAATCAGAAGAAATTTCAACTGGAACGAAGAAAAACTCACAGAAAGAAAAAGCAGAGACTCAAACGAGTTCAAGTGAA
GAATCAGAATTTTTAACCGTAGATGTCAAGGGTGCAGTCAAAAATCCAGGTATTTATCAACTGAAAAAGACTAGCCGTAT
CAATGATGCAATTCAAAAAGCGGGTGGTTTAACGACAGATGCTGACAGCAAGTCTATCAATTTGGCGCAAAAACTAACAG
ATGAAGCTGTTGTTTATGTGGCAACTGTTGGTGAGAATGCGACAAGTGTTGCAAGTGGAACAGGACAATCTTCAACGTTA
GGAACTAGTGAAGTCGCATCGCAAAAAGGGAATAAGGTCAATCTAAATACAGCTGATTTATCTGAGCTGCAGACCATTTC
TGGTATTGGTCAAAAACGTGCACAAGATATTTTAGATTATCGTGAGGCAAACGGGAAATTTAATTCCGTTGATGACCTGA
AAAATGTATCAGGAGTAGGTGCTAAAACACTAGAGAAATTGAAGGAATATGTCACAGTGGATTAA

Domains

Predicted by InterproScan.

SLBB domain (SLBB)

(87-140)

Helix-hairpin-helix motif (HHH_3)

(169-232)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A7L8W7D7

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comEA/celA/cilE Streptococcus mitis NCTC 12261

52.34

100

0.526
  comEA/celA/cilE Streptococcus pneumoniae TIGR4

52.34

100

0.526
  comEA/celA/cilE Streptococcus pneumoniae Rx1

52.34

100

0.526
  comEA/celA/cilE Streptococcus pneumoniae D39

52.34

100

0.526
  comEA/celA/cilE Streptococcus pneumoniae R6

52.34

100

0.526
  comEA/celA/cilE Streptococcus mitis SK321

51.073

99.573

0.509
  comEA Streptococcus thermophilus LMD-9

43.59

100

0.436
  comEA Lactococcus lactis subsp. cremoris KW2

42.489

99.573

0.423

Multiple sequence alignment