Detailed information    

insolico Bioinformatically predicted

Overview


Name   prx   Type   Regulator
Locus tag   FIU13_RS00025 Genome accession   NZ_CP040997
Coordinates   1874..2056 (+) Length   60 a.a.
NCBI ID   WP_029714017.1    Uniprot ID   A0A5S4TLJ0
Organism   Streptococcus pyogenes strain FDAARGOS_774     
Function   Inhibit ComR activation (predicted from homology)   
Competence regulation

Related MGE


Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
Prophage 271..5718 1874..2056 within 0


Gene organization within MGE regions


Location: 271..5718
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  FIU13_RS00010 (FIU13_00010) - 271..510 (-) 240 WP_011054447.1 hypothetical protein -
  FIU13_RS00015 (FIU13_00015) - 774..1025 (-) 252 WP_011054448.1 hypothetical protein -
  FIU13_RS10060 - 1166..1312 (-) 147 WP_011054449.1 hypothetical protein -
  FIU13_RS00020 (FIU13_00020) - 1466..1675 (+) 210 WP_011054450.1 helix-turn-helix domain-containing protein -
  FIU13_RS00025 (FIU13_00025) prx 1874..2056 (+) 183 WP_029714017.1 hypothetical protein Regulator
  FIU13_RS10065 - 2279..2686 (+) 408 Protein_6 nucleoside-diphosphate kinase -
  FIU13_RS00040 (FIU13_00040) lepA 2810..4642 (+) 1833 WP_010922253.1 translation elongation factor 4 -
  FIU13_RS00045 (FIU13_00045) slc2 4900..5718 (+) 819 WP_029714016.1 LPXTG-anchored collagen-like adhesin Scl2/SclB -

Sequence


Protein


Download         Length: 60 a.a.        Molecular weight: 6890.90 Da        Isoelectric Point: 4.1947

>NTDB_id=368578 FIU13_RS00025 WP_029714017.1 1874..2056(+) (prx) [Streptococcus pyogenes strain FDAARGOS_774]
MLTYDEFKQAIDNGYITADTVAIVRKNGLIFDYVLPHESVRSCEIVIEERVAEVMVELDK

Nucleotide


Download         Length: 183 bp        

>NTDB_id=368578 FIU13_RS00025 WP_029714017.1 1874..2056(+) (prx) [Streptococcus pyogenes strain FDAARGOS_774]
ATGCTAACATACGACGAGTTTAAGCAAGCGATTGACAATGGATATATCACAGCAGACACAGTAGCGATCGTGCGTAAAAA
CGGATTGATATTTGATTATGTGTTGCCGCACGAGTCTGTGAGATCGTGTGAGATTGTGATCGAGGAGAGGGTGGCGGAGG
TGATGGTGGAATTAGACAAATAA

Domains



No domain identified.



Secondary structure


Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure


Source ID Structure
  AlphaFold DB A0A5S4TLJ0

Transmembrane helices


Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.



Visualization of predicted probability:


Similar proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  prx Streptococcus pyogenes MGAS315

100

100

1

  prx Streptococcus pyogenes MGAS315

80

100

0.8

  prx Streptococcus pyogenes MGAS315

75

100

0.75

  prx Streptococcus pyogenes MGAS315

73.333

100

0.733

  prx Streptococcus pyogenes MGAS8232

73.333

100

0.733

  prx Streptococcus pyogenes MGAS315

80.952

70

0.567

  prx Streptococcus pyogenes MGAS315

78.571

70

0.55


Multiple sequence alignment