Detailed information NTG0367354

Bioinformatically predicted

Overview

• Name: vicR
• Type: Regulator
• Locus tag: FHI56_RS06755
• Genome accession: NZ_CP040804
• Coordinates: 1130545..1131252 (+)
• Length: 235 a.a.
• NCBI ID: WP_002884978.1
• Uniprot ID: A0AB33ZBK5
• Organism: Streptococcus salivarius strain LAB813
• Function: repress comCDE expression; repress comX expression (predicted from homology) Competence regulation

Genomic Context

Location: 1125545..1136252

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
FHI56_RS06730 (FHI56_06730)	-	1126318..1127085 (-)	768	WP_038675884.1	amino acid ABC transporter ATP-binding protein	-
FHI56_RS06735 (FHI56_06735)	-	1127272..1127922 (-)	651	WP_002886253.1	amino acid ABC transporter permease	-
FHI56_RS06740 (FHI56_06740)	-	1127934..1128632 (-)	699	WP_014633207.1	amino acid ABC transporter permease	-
FHI56_RS06745 (FHI56_06745)	-	1128650..1129483 (-)	834	WP_149561299.1	transporter substrate-binding domain-containing protein	-
FHI56_RS06750 (FHI56_06750)	-	1129493..1130260 (-)	768	WP_002885036.1	amino acid ABC transporter ATP-binding protein	-
FHI56_RS06755 (FHI56_06755)	vicR	1130545..1131252 (+)	708	WP_002884978.1	response regulator YycF	Regulator
FHI56_RS06760 (FHI56_06760)	vicK	1131245..1132585 (+)	1341	WP_002885062.1	cell wall metabolism sensor histidine kinase VicK	Regulator
FHI56_RS06765 (FHI56_06765)	vicX	1132591..1133403 (+)	813	WP_045772120.1	MBL fold metallo-hydrolase	Regulator
FHI56_RS06770 (FHI56_06770)	-	1133462..1133821 (+)	360	WP_004182609.1	YbaN family protein	-
FHI56_RS06775 (FHI56_06775)	-	1133993..1134269 (+)	277	Protein_1097	ISL3 family transposase	-
FHI56_RS06780 (FHI56_06780)	tnpA	1134507..1134980 (+)	474	WP_013990678.1	IS200/IS605 family transposase	-

Sequence

Protein

• Length: 235 a.a.
• Molecular weight: 27045.90 Da
• Isoelectric Point: 4.8387

>NTDB_id=367354 FHI56_RS06755 WP_002884978.1 1130545..1131252(+) (vicR) [Streptococcus salivarius strain LAB813]
MKKILVVDDERPISDIIKFNLTKEGYEVVTAFDGREALEQFEAEKPDLVILDLMLPELDGLEVAKEIRKTSHTPIIMLSA
KDSEFDKVIGLEIGADDYVTKPFSNRELLARIKAHLRRTETIETAAEESSNSGKQEISIGELIIVPDAFVAKKRGNEVEL
THREFELLFHLATHMGQVMTREHLLETVWGYDYFGDVRTVDVTIRRLREKIEDTPSRPEYILTRRGVGYYMKNYD

Nucleotide

• Length: 708 bp

>NTDB_id=367354 FHI56_RS06755 WP_002884978.1 1130545..1131252(+) (vicR) [Streptococcus salivarius strain LAB813]
ATGAAAAAAATTCTAGTTGTTGATGATGAAAGACCGATTTCGGATATCATCAAGTTTAATCTAACTAAAGAAGGTTATGA
AGTGGTTACAGCCTTTGATGGTCGTGAAGCTTTGGAGCAGTTTGAAGCTGAAAAGCCAGACTTGGTCATCCTGGACTTGA
TGTTGCCTGAACTAGATGGTTTAGAAGTTGCTAAGGAAATTCGAAAGACAAGTCACACACCGATTATCATGCTTTCCGCT
AAGGATAGCGAGTTTGATAAGGTTATCGGGCTAGAAATTGGGGCGGACGACTATGTGACGAAACCATTTTCTAATCGTGA
ATTGTTGGCACGTATCAAAGCTCACTTGCGTCGTACAGAGACTATTGAAACAGCAGCAGAAGAAAGCTCTAACTCTGGTA
AGCAGGAGATTTCAATTGGTGAGTTGATTATTGTTCCAGATGCGTTTGTTGCTAAAAAACGTGGAAATGAAGTCGAGCTC
ACACACCGTGAATTTGAGTTGCTTTTCCATCTGGCAACTCACATGGGACAAGTGATGACGCGTGAGCATTTACTTGAAAC
TGTTTGGGGTTATGACTATTTTGGTGATGTTCGTACGGTTGACGTAACCATTCGTCGTCTCCGTGAAAAAATTGAAGATA
CACCTAGTCGTCCTGAATATATTTTGACGCGTCGTGGTGTTGGTTATTATATGAAGAATTATGACTAG

Domains

Predicted by InterproScan.

• Response regulator receiver domain (Response_reg) (4-113)

• Transcriptional regulatory protein, C terminal (Trans_reg_C) (155-230)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vicR	Streptococcus mutans UA159	85.532	100	0.855
micA	Streptococcus pneumoniae Cp1015	80.687	99.149	0.8
covR	Streptococcus salivarius strain HSISS4	44.872	99.574	0.447
covR	Lactococcus lactis subsp. lactis strain DGCC12653	45.022	98.298	0.443
scnR	Streptococcus mutans UA159	38.559	100	0.387