Detailed information    

insolico Bioinformatically predicted

Overview

Name   vicK   Type   Regulator
Locus tag   FHI56_RS06760 Genome accession   NZ_CP040804
Coordinates   1131245..1132585 (+) Length   446 a.a.
NCBI ID   WP_002885062.1    Uniprot ID   A0A0F3HCD0
Organism   Streptococcus salivarius strain LAB813     
Function   repress comCDE expression; repress comX expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 1126245..1137585
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  FHI56_RS06730 (FHI56_06730) - 1126318..1127085 (-) 768 WP_038675884.1 amino acid ABC transporter ATP-binding protein -
  FHI56_RS06735 (FHI56_06735) - 1127272..1127922 (-) 651 WP_002886253.1 amino acid ABC transporter permease -
  FHI56_RS06740 (FHI56_06740) - 1127934..1128632 (-) 699 WP_014633207.1 amino acid ABC transporter permease -
  FHI56_RS06745 (FHI56_06745) - 1128650..1129483 (-) 834 WP_149561299.1 transporter substrate-binding domain-containing protein -
  FHI56_RS06750 (FHI56_06750) - 1129493..1130260 (-) 768 WP_002885036.1 amino acid ABC transporter ATP-binding protein -
  FHI56_RS06755 (FHI56_06755) vicR 1130545..1131252 (+) 708 WP_002884978.1 response regulator YycF Regulator
  FHI56_RS06760 (FHI56_06760) vicK 1131245..1132585 (+) 1341 WP_002885062.1 cell wall metabolism sensor histidine kinase VicK Regulator
  FHI56_RS06765 (FHI56_06765) vicX 1132591..1133403 (+) 813 WP_045772120.1 MBL fold metallo-hydrolase Regulator
  FHI56_RS06770 (FHI56_06770) - 1133462..1133821 (+) 360 WP_004182609.1 YbaN family protein -
  FHI56_RS06775 (FHI56_06775) - 1133993..1134269 (+) 277 Protein_1097 ISL3 family transposase -
  FHI56_RS06780 (FHI56_06780) tnpA 1134507..1134980 (+) 474 WP_013990678.1 IS200/IS605 family transposase -
  FHI56_RS06785 (FHI56_06785) - 1135119..1136333 (-) 1215 WP_004182608.1 aminoacyltransferase -
  FHI56_RS06790 (FHI56_06790) yidA 1136333..1137139 (-) 807 WP_004182607.1 sugar-phosphatase -

Sequence

Protein


Download         Length: 446 a.a.        Molecular weight: 50945.21 Da        Isoelectric Point: 5.1606

>NTDB_id=367355 FHI56_RS06760 WP_002885062.1 1131245..1132585(+) (vicK) [Streptococcus salivarius strain LAB813]
MTSIGLNITSFELALLFTLLFVAFYFIFLAYRDYRRVKNIRKLTKRVKSLMAGNYNEELRLKGDPELLELADSLNDLSDV
FRLTHENLAQEKNRLSSVLSYMSDGVIATNRRGQITMINSTAQRLLNLDYETATQMSILDLLDGENPYTYSELLSKTPEI
HLSRRDANDEFVTLRVNFALIRKESGFISGLVAVLHDATEQEKEERERRLFVSNVSHELRTPLTSVKSYLEALDDGALDE
EIAPNFIKVSLDETNRMMRMISDLLALSRIDNKSTQLDVEMTNFTAFMTYILNRFDQIKSQETNTGKTYEIIRDYPVNSI
WVEIDTDKMTQVVDNILNNAIKYSPDGGKITVSMKTTDSQLIVSISDQGLGIPKKDLPLIFDRFYRVDKARSRAQGGTGL
GLSIAKEIIKQHKGFIWAKSEYGKGSTFTIVLPYDKDAMMVDEWEM

Nucleotide


Download         Length: 1341 bp        

>NTDB_id=367355 FHI56_RS06760 WP_002885062.1 1131245..1132585(+) (vicK) [Streptococcus salivarius strain LAB813]
ATGACTAGTATTGGCTTAAACATCACAAGCTTTGAACTAGCCTTACTCTTTACGCTCCTCTTTGTGGCTTTCTACTTTAT
TTTTCTTGCATATCGTGATTATCGACGAGTCAAAAATATTCGAAAGTTGACCAAGAGGGTCAAGTCCTTAATGGCAGGTA
ACTATAACGAGGAGTTACGCTTAAAGGGTGATCCAGAGCTTTTAGAGCTAGCTGACAGCTTGAATGATTTATCGGATGTC
TTTCGTTTGACGCATGAAAATCTAGCCCAGGAAAAAAACCGCTTATCATCAGTCCTTTCTTACATGAGTGATGGGGTTAT
TGCGACAAATCGTCGTGGTCAAATTACCATGATTAATAGCACAGCTCAGCGTTTGTTGAATCTAGATTATGAAACAGCGA
CACAGATGTCCATTTTAGATTTATTAGATGGCGAAAATCCCTATACTTATAGTGAATTGCTCTCTAAGACTCCTGAAATT
CATTTGTCACGTCGAGATGCCAACGATGAGTTTGTGACCTTACGTGTTAATTTTGCCCTTATTCGTAAAGAATCAGGTTT
TATCTCAGGTCTGGTTGCTGTTCTTCACGATGCCACTGAGCAGGAAAAAGAAGAGCGTGAACGTCGACTTTTCGTCTCGA
ACGTTAGTCATGAGTTGCGTACACCTTTGACTTCTGTAAAATCCTATCTGGAGGCACTTGATGATGGAGCTCTCGATGAA
GAGATTGCCCCTAACTTTATCAAAGTTTCTTTGGATGAGACCAATCGTATGATGCGAATGATTTCTGACCTCTTGGCACT
GTCACGTATTGACAATAAGAGTACCCAACTTGACGTTGAGATGACCAATTTCACGGCCTTCATGACCTATATCTTGAATC
GTTTTGATCAGATTAAGAGTCAAGAAACCAATACAGGTAAAACTTACGAAATTATTCGAGATTATCCGGTAAACTCAATT
TGGGTAGAGATTGATACAGATAAGATGACCCAGGTCGTGGATAATATTCTTAATAATGCCATCAAGTATTCGCCTGATGG
TGGTAAGATTACAGTGTCTATGAAGACAACTGACTCACAGTTGATCGTTTCTATTTCTGACCAAGGTTTGGGTATTCCTA
AGAAAGATTTGCCTTTGATTTTCGACCGTTTTTACCGTGTTGATAAGGCAAGAAGTCGTGCCCAGGGTGGAACTGGTCTT
GGCTTGTCCATTGCAAAAGAAATTATTAAACAACATAAGGGCTTTATTTGGGCTAAGAGTGAGTATGGTAAAGGTTCAAC
TTTTACAATTGTGCTTCCATATGACAAGGATGCCATGATGGTTGATGAATGGGAGATGTAG

Domains

Predicted by InterproScan.

PAS fold (PAS)

(94-197)

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c)

(325-435)

His Kinase A (phospho-acceptor) domain (HisKA)

(208-272)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A0F3HCD0

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vicK Streptococcus mutans UA159

73.671

92.825

0.684
  micB Streptococcus pneumoniae Cp1015

67.667

97.085

0.657

Multiple sequence alignment