Detailed information NTG0036581

Bioinformatically predicted

Overview

• Name: clpP
• Type: Regulator
• Locus tag: SMUNN2025_RS02435
• Genome accession: NC_013928
• Coordinates: 478202..478816 (+)
• Length: 204 a.a.
• NCBI ID: WP_255262943.1
• Uniprot ID: -
• Organism: Streptococcus mutans NN2025
• Function: degradation of ComX; require for competence development (at the early growth phase); repress competence development (at the mid-logarithmic growth phase) (predicted from homology) Competence regulation

Genomic Context

Location: 473202..483816

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
SMUNN2025_RS02420 (SmuNN2025_0442)	-	474679..475773 (+)	1095	WP_002265957.1	cystathionine gamma-synthase	-
SMUNN2025_RS02425 (SmuNN2025_0443)	-	475788..476951 (+)	1164	WP_002274233.1	MalY/PatB family protein	-
SMUNN2025_RS02430 (SmuNN2025_0444)	upp	477264..477893 (+)	630	WP_002262598.1	uracil phosphoribosyltransferase	-
SMUNN2025_RS02435 (SmuNN2025_0445)	clpP	478202..478816 (+)	615	WP_255262943.1	ATP-dependent Clp protease proteolytic subunit ClpP	Regulator
SMUNN2025_RS02440 (SmuNN2025_0446)	-	478932..479372 (+)	441	WP_002270498.1	YlbF family regulator	-
SMUNN2025_RS02445 (SmuNN2025_0447)	-	479379..479627 (+)	249	WP_002277433.1	YlbG family protein	-
SMUNN2025_RS02450 (SmuNN2025_0448)	-	479730..480902 (+)	1173	WP_002262675.1	ABC transporter substrate-binding protein	-
SMUNN2025_RS02455 (SmuNN2025_0449)	-	480986..481855 (+)	870	WP_002262676.1	branched-chain amino acid ABC transporter permease	-
SMUNN2025_RS02460 (SmuNN2025_0450)	-	481859..482815 (+)	957	WP_002262677.1	branched-chain amino acid ABC transporter permease	-
SMUNN2025_RS02465 (SmuNN2025_0451)	-	482815..483579 (+)	765	WP_002262678.1	ABC transporter ATP-binding protein	-

Sequence

Protein

• Length: 204 a.a.
• Molecular weight: 22665.10 Da
• Isoelectric Point: 5.3673

>NTDB_id=36581 SMUNN2025_RS02435 WP_255262943.1 478202..478816(+) (clpP) [Streptococcus mutans NN2025]
MELKEKYSMIPVVIEQTSRGERSYDIYSRLLKDRIIMLTGPVEDNMANSIIAQLLFLDAQDNTKDIYLYINSPGGSVSAG
LAIVDTMNFIKSDVQTIVMGIAASMGTIIASSGAKGKRFMLPNAEYLIHQPMGGTGGGTQQSDMAIAAEQLLKTRKKLEK
ILSDNSGKTVKQIHKDAERDYWMDAKETLKYGFIDEIMENNELK

Nucleotide

• Length: 615 bp

>NTDB_id=36581 SMUNN2025_RS02435 WP_255262943.1 478202..478816(+) (clpP) [Streptococcus mutans NN2025]
ATTGAATTAAAGGAGAAATACAGTATGATTCCTGTAGTTATTGAACAAACGAGCCGTGGTGAACGCTCTTATGATATTTA
TTCACGTCTATTAAAAGATCGTATTATTATGTTGACTGGTCCTGTTGAAGACAATATGGCAAATTCCATTATTGCTCAGT
TACTGTTTCTTGATGCACAAGATAATACCAAAGACATTTATCTTTATATTAATTCACCGGGTGGTTCTGTTTCAGCTGGT
CTTGCTATTGTTGATACGATGAACTTTATTAAGTCTGATGTTCAAACGATTGTTATGGGTATTGCTGCTTCCATGGGAAC
AATCATCGCTTCTAGCGGTGCCAAAGGAAAACGTTTTATGTTACCAAATGCAGAATATCTTATCCATCAGCCAATGGGCG
GTACAGGCGGTGGCACACAGCAGTCTGATATGGCTATTGCTGCCGAACAATTGCTTAAAACACGCAAAAAATTAGAAAAG
ATTCTATCGGATAATTCTGGAAAAACAGTAAAACAAATTCATAAGGATGCTGAACGTGATTATTGGATGGATGCTAAGGA
AACATTAAAGTATGGCTTCATCGATGAAATCATGGAAAATAATGAATTAAAATAA

Domains

Predicted by InterproScan.

• Clp protease (CLP_protease) (19-200)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpP	Streptococcus mutans UA159	99.51	100	0.995
clpP	Streptococcus pyogenes JRS4	90.306	96.078	0.868
clpP	Streptococcus pyogenes MGAS315	90.306	96.078	0.868
clpP	Lactococcus lactis subsp. lactis strain DGCC12653	87.755	96.078	0.843
clpP	Streptococcus thermophilus LMD-9	87.245	96.078	0.838
clpP	Lactococcus lactis subsp. cremoris KW2	87.245	96.078	0.838
clpP	Streptococcus thermophilus LMG 18311	87.245	96.078	0.838
clpP	Streptococcus pneumoniae Rx1	86.154	95.588	0.824
clpP	Streptococcus pneumoniae D39	86.154	95.588	0.824
clpP	Streptococcus pneumoniae R6	86.154	95.588	0.824
clpP	Streptococcus pneumoniae TIGR4	86.154	95.588	0.824
clpP	Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819	57.513	94.608	0.544
clpP	Bacillus subtilis subsp. subtilis str. 168	55.838	96.569	0.539