Detailed information    

insolico Bioinformatically predicted

Overview

Name   micA   Type   Regulator
Locus tag   SMI_RS05965 Genome accession   NC_013853
Coordinates   1172379..1173086 (-) Length   235 a.a.
NCBI ID   WP_000722073.1    Uniprot ID   -
Organism   Streptococcus mitis B6     
Function   repress competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 1167379..1178086
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SMI_RS05945 (smi_1173) - 1168015..1169733 (+) 1719 WP_000121684.1 phospho-sugar mutase -
  SMI_RS05950 (smi_1174) - 1169845..1170192 (+) 348 WP_000434642.1 thiol reductase thioredoxin -
  SMI_RS05955 (smi_1175) vicX 1170226..1171035 (-) 810 WP_000004959.1 MBL fold metallo-hydrolase Regulator
  SMI_RS05960 (smi_1176) micB 1171037..1172386 (-) 1350 WP_000593410.1 cell wall metabolism sensor histidine kinase VicK Regulator
  SMI_RS05965 (smi_1177) micA 1172379..1173086 (-) 708 WP_000722073.1 response regulator YycF Regulator
  SMI_RS05970 (smi_1178) mutY 1173212..1174393 (-) 1182 WP_000267474.1 A/G-specific adenine glycosylase -
  SMI_RS05975 (smi_1179) pta 1174703..1175677 (-) 975 WP_000451589.1 phosphate acetyltransferase -
  SMI_RS05980 (smi_1180) - 1175721..1176617 (-) 897 WP_001209981.1 RluA family pseudouridine synthase -
  SMI_RS05985 (smi_1181) - 1176614..1177432 (-) 819 WP_000799056.1 NAD kinase -

Sequence

Protein


Download         Length: 235 a.a.        Molecular weight: 27155.95 Da        Isoelectric Point: 4.6177

>NTDB_id=36321 SMI_RS05965 WP_000722073.1 1172379..1173086(-) (micA) [Streptococcus mitis B6]
MKKILIVDDEKPISDIIKFNMTKEGYEVVTAFNGREALEQFEAEQPDIIILDLMLPEIDGLEVAKTIRKTSSVPIIMLSA
KDTEFDKVIGLELGADDYVTKPFSNRELQARVKALLRRTDLVSVDNQESDEKKTQPLQFGDLEIVPDAYVAKKYGEELDL
THREFELLYHLASHIGQVITREHLLETVWGYDYFGDVRTVDVTIRRLREKIEDTPSRPEYILTRRGVGYYMRNND

Nucleotide


Download         Length: 708 bp        

>NTDB_id=36321 SMI_RS05965 WP_000722073.1 1172379..1173086(-) (micA) [Streptococcus mitis B6]
ATGAAAAAAATATTAATTGTAGATGATGAAAAACCAATCTCGGATATTATCAAGTTTAATATGACCAAGGAAGGTTACGA
GGTTGTAACTGCTTTTAACGGTCGTGAAGCACTAGAGCAATTTGAAGCAGAGCAACCAGATATTATTATTCTGGATTTGA
TGCTGCCGGAAATTGATGGTTTAGAAGTTGCTAAGACTATTCGCAAGACTAGTAGTGTACCTATTATCATGCTTTCTGCT
AAAGATACCGAATTTGATAAGGTTATCGGTTTAGAGCTTGGGGCGGATGACTATGTAACCAAACCCTTCTCAAATCGTGA
GTTGCAGGCGCGTGTTAAAGCTCTTCTTCGTCGCACGGACTTGGTTTCTGTAGATAATCAAGAATCAGATGAAAAGAAAA
CCCAACCCTTGCAATTTGGGGACTTGGAGATTGTTCCAGATGCCTATGTAGCTAAGAAATACGGTGAAGAACTAGATCTA
ACCCACCGTGAATTTGAACTCTTGTATCATTTGGCTTCTCATATAGGTCAAGTTATTACGCGTGAACACTTGCTTGAAAC
GGTCTGGGGTTATGATTATTTCGGTGATGTTCGAACAGTTGACGTGACTATCAGACGTTTACGTGAGAAGATTGAAGATA
CACCAAGTCGTCCTGAGTATATTCTAACACGTCGCGGTGTTGGTTATTATATGAGAAATAATGATTAA

Domains

Predicted by InterproScan.

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(155-230)

Response regulator receiver domain (Response_reg)

(4-112)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  micA Streptococcus pneumoniae Cp1015

93.162

99.574

0.928
  vicR Streptococcus mutans UA159

76.596

100

0.766
  covR Lactococcus lactis subsp. lactis strain DGCC12653

43.723

98.298

0.43
  covR Streptococcus salivarius strain HSISS4

43.723

98.298

0.43
  scnR Streptococcus mutans UA159

37.768

99.149

0.374

Multiple sequence alignment