Detailed information NTG0036320

Bioinformatically predicted

Overview

• Name: micB
• Type: Regulator
• Locus tag: SMI_RS05960
• Genome accession: NC_013853
• Coordinates: 1171037..1172386 (-)
• Length: 449 a.a.
• NCBI ID: WP_000593410.1
• Uniprot ID: D3H977
• Organism: Streptococcus mitis B6
• Function: repress competence development (predicted from homology) Competence regulation

Genomic Context

Location: 1166037..1177386

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
SMI_RS05945 (smi_1173)	-	1168015..1169733 (+)	1719	WP_000121684.1	phospho-sugar mutase	-
SMI_RS05950 (smi_1174)	-	1169845..1170192 (+)	348	WP_000434642.1	thiol reductase thioredoxin	-
SMI_RS05955 (smi_1175)	vicX	1170226..1171035 (-)	810	WP_000004959.1	MBL fold metallo-hydrolase	Regulator
SMI_RS05960 (smi_1176)	micB	1171037..1172386 (-)	1350	WP_000593410.1	cell wall metabolism sensor histidine kinase VicK	Regulator
SMI_RS05965 (smi_1177)	micA	1172379..1173086 (-)	708	WP_000722073.1	response regulator YycF	Regulator
SMI_RS05970 (smi_1178)	mutY	1173212..1174393 (-)	1182	WP_000267474.1	A/G-specific adenine glycosylase	-
SMI_RS05975 (smi_1179)	pta	1174703..1175677 (-)	975	WP_000451589.1	phosphate acetyltransferase	-
SMI_RS05980 (smi_1180)	-	1175721..1176617 (-)	897	WP_001209981.1	RluA family pseudouridine synthase	-

Sequence

Protein

• Length: 449 a.a.
• Molecular weight: 51338.67 Da
• Isoelectric Point: 4.5998

>NTDB_id=36320 SMI_RS05960 WP_000593410.1 1171037..1172386(-) (micB) [Streptococcus mitis B6]
MIKLIKDTVLTSDSIFILILLGFILVVTLLLLENRRDNIRLKQINQKVKDLITGDYSQVLDMQGSSEITNITNNLNDLSE
VIRLTQENLEQESKRLNSILSYMTDGVLATNRRGQITMINDMAKKQLGVQKEDVLNKSILELLEIVDEYELRDLITQIPE
LMIDSQDANGEYLSLRVRFALVRRESGFISGLVAVLHDTTEQEKEERERRLFVSNVSHELRTPLTSVKSYLEALDEGALS
EPVAPDFIKVSLDETNRMMRMVTDLLHLSRIDNATSHLDVELINFTAFITFILNRFDQIRGQDEEKKYELVRDYPITSVW
IEIDTDKMTQVIDNILNNAIKYSPDGGKITVTMKTTDDQMILSISDQGLGIPKQDLPRIFDRFYRVDRARSRAQGGTGLG
LAIAKEIIKQHNGFIWAKSEYGKGSTFTIVLPYDKDAVKEEVWEDEVED

Nucleotide

• Length: 1350 bp

>NTDB_id=36320 SMI_RS05960 WP_000593410.1 1171037..1172386(-) (micB) [Streptococcus mitis B6]
ATGATTAAATTAATAAAAGATACCGTTTTAACCAGTGATTCTATCTTTATCCTTATTCTACTTGGCTTTATTTTAGTGGT
GACCTTGCTTTTACTAGAAAATCGTCGGGATAATATTCGGTTGAAGCAGATTAACCAAAAAGTTAAAGACCTGATTACAG
GAGATTATTCTCAGGTATTGGATATGCAGGGAAGTTCTGAAATCACTAATATTACCAATAATCTCAATGATTTATCAGAA
GTAATTCGCTTGACTCAAGAAAATCTGGAACAAGAGAGTAAACGATTGAATAGTATCCTCTCATACATGACAGATGGTGT
CCTTGCTACCAATCGTCGTGGCCAGATTACCATGATTAATGACATGGCTAAGAAACAGCTAGGCGTTCAGAAGGAAGATG
TTCTTAATAAAAGTATTCTAGAATTGCTTGAGATTGTAGATGAGTATGAACTTCGTGATTTGATTACCCAAATTCCTGAA
CTCATGATTGATTCTCAGGATGCCAATGGTGAATATCTGAGCCTTCGTGTACGCTTTGCCTTGGTTCGTCGAGAATCAGG
CTTCATTTCTGGTCTGGTTGCAGTTTTACACGATACGACGGAGCAGGAGAAGGAAGAGCGCGAACGAAGACTCTTTGTTT
CTAACGTTAGTCATGAGCTACGGACGCCCCTAACTAGTGTAAAATCCTATCTTGAAGCTTTGGACGAGGGTGCCTTGTCA
GAACCTGTCGCTCCAGACTTTATTAAAGTATCTCTAGATGAAACCAACCGTATGATGAGGATGGTAACAGACCTTCTTCA
TCTTTCACGTATTGATAATGCAACCAGTCACCTAGATGTGGAATTGATTAACTTTACTGCTTTTATTACCTTTATCCTCA
ACCGTTTTGATCAGATAAGAGGGCAGGATGAAGAGAAGAAATACGAACTGGTGAGAGATTACCCAATTACCTCAGTCTGG
ATAGAGATAGATACAGATAAGATGACACAGGTGATTGATAATATTCTTAACAATGCCATCAAGTATTCGCCAGATGGTGG
AAAAATCACAGTGACCATGAAGACGACTGATGATCAGATGATTTTATCTATTTCAGACCAAGGATTGGGTATTCCTAAGC
AGGATTTACCACGTATTTTTGACCGTTTTTATCGTGTGGATCGTGCTAGAAGTCGTGCCCAAGGAGGTACTGGTTTAGGA
CTAGCTATTGCTAAAGAGATTATCAAACAACATAATGGTTTTATTTGGGCCAAGAGTGAATATGGTAAGGGATCAACCTT
CACCATTGTACTCCCTTATGATAAGGATGCAGTGAAAGAAGAAGTATGGGAGGACGAAGTAGAAGACTAG

Domains

Predicted by InterproScan.

• PAS fold (PAS) (95-198)

• His Kinase A (phospho-acceptor) domain (HisKA) (209-273)

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (324-434)

3D structure

• AlphaFold DB: D3H977

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
micB	Streptococcus pneumoniae Cp1015	89.749	97.773	0.878
vicK	Streptococcus mutans UA159	72.886	89.532	0.653