Detailed information    

insolico Bioinformatically predicted

Overview

Name   dprA/cilB/dalA   Type   Machinery gene
Locus tag   FD735_RS05840 Genome accession   NZ_CP040231
Coordinates   1104014..1104862 (-) Length   282 a.a.
NCBI ID   WP_139658720.1    Uniprot ID   A0A5B7Y6H2
Organism   Streptococcus sp. 1643     
Function   ssDNA binding; loading RecA onto ssDNA (predicted from homology)   
DNA processing

Genomic Context

Location: 1099014..1109862
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  FD735_RS05820 (FD735_05820) - 1099917..1100573 (-) 657 WP_139658719.1 MmcQ/YjbR family DNA-binding protein -
  FD735_RS05825 (FD735_05825) - 1100617..1101249 (-) 633 WP_000638806.1 copper homeostasis protein CutC -
  FD735_RS05830 (FD735_05830) - 1101343..1101702 (-) 360 WP_007516860.1 YbaN family protein -
  FD735_RS05835 (FD735_05835) topA 1101809..1103896 (-) 2088 WP_084921813.1 type I DNA topoisomerase -
  FD735_RS05840 (FD735_05840) dprA/cilB/dalA 1104014..1104862 (-) 849 WP_139658720.1 DNA-processing protein DprA Machinery gene
  FD735_RS05845 (FD735_05845) - 1104944..1105567 (-) 624 WP_139658721.1 hypothetical protein -
  FD735_RS05850 (FD735_05850) lepA 1105710..1107533 (-) 1824 WP_139658722.1 translation elongation factor 4 -
  FD735_RS05855 (FD735_05855) - 1107612..1108340 (-) 729 WP_139658723.1 metallophosphoesterase family protein -

Sequence

Protein


Download         Length: 282 a.a.        Molecular weight: 31270.74 Da        Isoelectric Point: 5.2027

>NTDB_id=362650 FD735_RS05840 WP_139658720.1 1104014..1104862(-) (dprA/cilB/dalA) [Streptococcus sp. 1643]
MKITNYEIYKLRKAGLSNQQILTVLEYDETVDQELLLGDIAELSGCRNPAVFMERYFQIDDAQLEKEFQKFPSFSILDDC
YPWDLSEIYDPPALLFYKGNLDLLKFPKVALVGSRSCSNQGAKSVQKVIQGLENELIVVSGLAKGIDTAAHMAALQNGGR
TIAVIGTGLDVFYPRANKRLQEHIGNHHLVLSEYGPGEEPLKFHFPARNRIIAGLCRGVIVAEARMRSGSLITCERAMEE
GRDVFAIPGNVLDGHSDGCHHLIQEGAKLISSGQDVLAEFEF

Nucleotide


Download         Length: 849 bp        

>NTDB_id=362650 FD735_RS05840 WP_139658720.1 1104014..1104862(-) (dprA/cilB/dalA) [Streptococcus sp. 1643]
ATGAAGATCACAAACTATGAGATTTACAAATTGAGAAAAGCTGGGCTGAGCAATCAACAAATTTTAACAGTTCTTGAATA
CGATGAGACTGTAGATCAGGAGCTTTTGCTAGGTGATATTGCGGAACTATCGGGGTGCCGTAATCCTGCTGTCTTTATGG
AACGCTATTTCCAGATAGATGATGCACAGTTGGAGAAGGAGTTTCAAAAATTCCCATCCTTCTCGATTCTAGACGACTGT
TATCCTTGGGATCTGAGTGAGATTTATGACCCTCCAGCTCTTTTGTTTTACAAAGGGAATCTGGATTTATTGAAATTTCC
AAAGGTTGCTCTTGTAGGGAGTCGTTCATGTTCGAATCAGGGAGCAAAGTCGGTTCAGAAAGTCATTCAAGGTTTGGAAA
ACGAGTTAATCGTGGTCAGTGGTTTAGCCAAAGGGATTGATACAGCTGCCCATATGGCTGCACTCCAGAATGGAGGAAGA
ACAATTGCTGTCATTGGAACAGGATTGGATGTCTTTTATCCCCGAGCCAATAAACGTTTGCAGGAACACATTGGCAATCA
CCATTTGGTACTTAGCGAATACGGACCAGGTGAGGAACCCTTGAAATTTCACTTTCCAGCTCGTAATCGCATCATAGCAG
GACTGTGCCGTGGCGTTATTGTAGCAGAGGCAAGGATGCGTTCTGGTAGTCTCATCACCTGTGAGCGAGCTATGGAGGAA
GGGCGTGATGTTTTTGCCATTCCGGGAAACGTTTTAGATGGCCATTCAGATGGTTGCCACCACCTGATTCAAGAGGGAGC
AAAGCTGATTTCCAGTGGTCAAGATGTGCTGGCTGAGTTTGAATTTTAA

Domains

Predicted by InterproScan.

DNA recombination-mediator protein A (DNA_processg_A)

(75-271)

DNA processing protein A sterile alpha motif domain (SAM_DprA)

(3-64)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A5B7Y6H2

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  dprA/cilB/dalA Streptococcus mitis NCTC 12261

89.716

100

0.897
  dprA/cilB/dalA Streptococcus pneumoniae Rx1

89.362

100

0.894
  dprA/cilB/dalA Streptococcus pneumoniae D39

89.362

100

0.894
  dprA/cilB/dalA Streptococcus pneumoniae R6

89.362

100

0.894
  dprA/cilB/dalA Streptococcus pneumoniae TIGR4

89.362

100

0.894
  dprA/cilB/dalA Streptococcus mitis SK321

88.652

100

0.887
  dprA Streptococcus mutans UA159

60

99.291

0.596
  dprA Lactococcus lactis subsp. cremoris KW2

54.286

99.291

0.539
  dprA Acinetobacter baylyi ADP1

39.163

93.262

0.365

Multiple sequence alignment