Detailed information    

insolico Bioinformatically predicted

Overview

Name   comEA/celA/cilE   Type   Machinery gene
Locus tag   FD735_RS03830 Genome accession   NZ_CP040231
Coordinates   701649..702299 (+) Length   216 a.a.
NCBI ID   WP_139658522.1    Uniprot ID   A0A5B7Y5G1
Organism   Streptococcus sp. 1643     
Function   dsDNA binding to the cell surface (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 696649..707299
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  FD735_RS03795 (FD735_03795) cvfB 696923..697777 (+) 855 WP_009730017.1 RNA-binding virulence regulatory protein CvfB -
  FD735_RS03800 (FD735_03800) - 697789..698394 (+) 606 WP_042902395.1 GrpB family protein -
  FD735_RS03805 (FD735_03805) - 698391..698606 (+) 216 WP_001232084.1 YozE family protein -
  FD735_RS03810 (FD735_03810) - 698687..699673 (+) 987 WP_139658518.1 PhoH family protein -
  FD735_RS03815 (FD735_03815) ald 699724..700836 (-) 1113 WP_139658520.1 alanine dehydrogenase -
  FD735_RS03825 (FD735_03825) - 701013..701582 (+) 570 WP_139658521.1 GNAT family N-acetyltransferase -
  FD735_RS03830 (FD735_03830) comEA/celA/cilE 701649..702299 (+) 651 WP_139658522.1 helix-hairpin-helix domain-containing protein Machinery gene
  FD735_RS03835 (FD735_03835) comEC/celB 702283..704514 (+) 2232 WP_139658523.1 DNA internalization-related competence protein ComEC/Rec2 Machinery gene
  FD735_RS09910 - 704664..704878 (+) 215 Protein_691 hypothetical protein -
  FD735_RS03840 (FD735_03840) - 704911..705504 (+) 594 WP_139658524.1 ATP-binding cassette domain-containing protein -
  FD735_RS03845 (FD735_03845) - 705501..706685 (+) 1185 WP_139658525.1 hypothetical protein -

Sequence

Protein


Download         Length: 216 a.a.        Molecular weight: 23113.27 Da        Isoelectric Point: 5.9255

>NTDB_id=362639 FD735_RS03830 WP_139658522.1 701649..702299(+) (comEA/celA/cilE) [Streptococcus sp. 1643]
MEAIIEKIKEYKIIVICAGLGLALGGFFLLKPSTQTPVKETNLQAEVSAVSKDSSSEKEVKKEEKEESAEQDIITVDVKG
AVKSPGIYDLPVGSRVHDAVQKAGGLTEEADSKSLNLAQKVSDEALVYVPTKGEEAASQQAASGTTPSTSKDKKVNLNKA
SLEELKQVKGLGGKRAQDIIDHREANGKFKSVDELKKVSGIGAKTIEKLKDYVTVD

Nucleotide


Download         Length: 651 bp        

>NTDB_id=362639 FD735_RS03830 WP_139658522.1 701649..702299(+) (comEA/celA/cilE) [Streptococcus sp. 1643]
ATGGAAGCAATTATCGAGAAAATCAAAGAGTATAAAATCATTGTCATCTGTGCTGGTTTGGGTTTGGCCTTGGGAGGATT
TTTCCTACTAAAGCCATCTACACAGACACCTGTGAAAGAAACAAACTTGCAAGCTGAAGTCTCGGCCGTTTCAAAGGATT
CATCTTCTGAAAAAGAAGTCAAGAAGGAAGAAAAGGAAGAGTCTGCTGAACAAGATATAATAACAGTAGATGTCAAGGGT
GCTGTTAAATCGCCAGGGATTTATGATTTACCAGTTGGGAGTCGTGTTCATGATGCTGTTCAGAAGGCAGGTGGCTTGAC
AGAGGAAGCAGATAGTAAATCGCTCAATCTCGCTCAGAAAGTCAGTGACGAGGCTCTTGTCTATGTTCCAACTAAGGGAG
AAGAAGCGGCTAGTCAGCAGGCTGCCTCTGGAACGACTCCTTCGACAAGTAAAGATAAGAAGGTCAACCTAAATAAAGCT
AGTCTGGAAGAACTAAAACAGGTCAAAGGCTTGGGAGGAAAACGAGCCCAGGATATTATTGATCATCGTGAGGCAAATGG
CAAATTCAAGTCGGTAGATGAATTAAAGAAAGTCTCTGGTATTGGCGCTAAGACCATAGAAAAGCTAAAAGATTATGTCA
CAGTGGATTAA

Domains

Predicted by InterproScan.

Helix-hairpin-helix motif (HHH_3)

(152-214)

SLBB domain (SLBB)

(76-126)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A5B7Y5G1

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comEA/celA/cilE Streptococcus mitis NCTC 12261

92.13

100

0.921
  comEA/celA/cilE Streptococcus pneumoniae TIGR4

91.204

100

0.912
  comEA/celA/cilE Streptococcus pneumoniae R6

89.352

100

0.894
  comEA/celA/cilE Streptococcus pneumoniae D39

89.352

100

0.894
  comEA/celA/cilE Streptococcus pneumoniae Rx1

89.352

100

0.894
  comEA/celA/cilE Streptococcus mitis SK321

88.426

100

0.884
  comEA Lactococcus lactis subsp. cremoris KW2

40.991

100

0.421

Multiple sequence alignment