Detailed information NTG0361158

Bioinformatically predicted

Overview

• Name: clpP
• Type: Regulator
• Locus tag: FCJ76_RS17780
• Genome accession: NZ_CP039935
• Coordinates: 3402074..3402667 (+)
• Length: 197 a.a.
• NCBI ID: WP_003228214.1
• Uniprot ID: A0A199WEF2
• Organism: Bacillus subtilis strain H19
• Function: degradation of ComK; degradation of DegU (predicted from homology) Competence regulation

Genomic Context

Location: 3397074..3407667

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
FCJ76_RS17745	-	3398060..3398644 (+)	585	WP_175405003.1	TetR family transcriptional regulator	-
FCJ76_RS17750	psmA	3398726..3399061 (+)	336	WP_014480966.1	SMR family transporter	-
FCJ76_RS17755	psmB	3399061..3399381 (+)	321	WP_021480661.1	QacE family quaternary ammonium compound efflux SMR transporter	-
FCJ76_RS17760	yvdQ	3399417..3399929 (-)	513	WP_134982547.1	DUF3231 family protein	-
FCJ76_RS21575	-	3399949..3400218 (-)	270	WP_137201035.1	poly-gamma-glutamate hydrolase family protein	-
FCJ76_RS17770	cotR	3400408..3401370 (+)	963	WP_024573362.1	sporulation hydrolase CotR	-
FCJ76_RS17780	clpP	3402074..3402667 (+)	594	WP_003228214.1	ATP-dependent Clp endopeptidase proteolytic subunit ClpP	Regulator
FCJ76_RS17785	pgmB	3402730..3403404 (-)	675	WP_137201037.1	beta-phosphoglucomutase	-
FCJ76_RS17790	malL	3403401..3405086 (-)	1686	WP_086344354.1	oligo-1,6-glucosidase	-
FCJ76_RS17795	mdxK	3405079..3407346 (-)	2268	WP_137201176.1	maltose phosphorylase	-

Sequence

Protein

• Length: 197 a.a.
• Molecular weight: 21682.00 Da
• Isoelectric Point: 4.9416

>NTDB_id=361158 FCJ76_RS17780 WP_003228214.1 3402074..3402667(+) (clpP) [Bacillus subtilis strain H19]
MNLIPTVIEQTNRGERAYDIYSRLLKDRIIMLGSAIDDNVANSIVSQLLFLAAEDPEKEISLYINSPGGSITAGMAIYDT
MQFIKPKVSTICIGMAASMGAFLLAAGEKGKRYALPNSEVMIHQPLGGAQGQATEIEIAAKRILLLRDKLNKVLAERTGQ
PLEVIERDTDRDNFKSAEEALEYGLIDKILTHTEDKK

Nucleotide

• Length: 594 bp

>NTDB_id=361158 FCJ76_RS17780 WP_003228214.1 3402074..3402667(+) (clpP) [Bacillus subtilis strain H19]
ATGAATTTAATACCTACAGTCATTGAACAAACGAACCGCGGGGAAAGAGCGTATGACATTTATTCTCGTCTATTAAAGGA
TCGTATCATCATGCTTGGATCTGCGATTGATGACAACGTTGCGAACTCCATCGTGTCACAGCTTTTATTCTTAGCAGCAG
AAGACCCTGAAAAAGAAATTTCTCTTTACATCAACAGCCCGGGCGGCTCTATTACAGCCGGTATGGCGATCTATGATACC
ATGCAGTTTATTAAGCCGAAGGTATCTACAATTTGTATCGGTATGGCTGCGTCAATGGGAGCGTTCCTGCTTGCAGCCGG
CGAAAAAGGCAAACGCTATGCGCTTCCAAACAGTGAAGTCATGATTCACCAGCCTCTTGGCGGTGCGCAAGGTCAGGCGA
CAGAAATTGAAATTGCCGCGAAACGCATTCTCTTGCTTCGCGACAAATTAAACAAAGTCCTTGCTGAACGTACTGGCCAG
CCGCTTGAAGTGATCGAACGCGACACAGACCGTGATAACTTCAAGTCTGCTGAAGAAGCGCTTGAATACGGCCTGATTGA
CAAAATTTTGACTCACACAGAAGATAAAAAGTAA

Domains

Predicted by InterproScan.

• Clp protease (CLP_protease) (13-192)

3D structure

• AlphaFold DB: A0A199WEF2

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpP	Bacillus subtilis subsp. subtilis str. 168	100	100	1
clpP	Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819	68.617	95.431	0.655
clpP	Streptococcus thermophilus LMG 18311	58.163	99.492	0.579
clpP	Streptococcus thermophilus LMD-9	58.163	99.492	0.579
clpP	Streptococcus pneumoniae D39	57.812	97.462	0.563
clpP	Streptococcus pneumoniae Rx1	57.812	97.462	0.563
clpP	Streptococcus pneumoniae R6	57.812	97.462	0.563
clpP	Streptococcus pneumoniae TIGR4	57.812	97.462	0.563
clpP	Lactococcus lactis subsp. cremoris KW2	57.895	96.447	0.558
clpP	Streptococcus pyogenes JRS4	56.122	99.492	0.558
clpP	Streptococcus pyogenes MGAS315	56.122	99.492	0.558
clpP	Streptococcus mutans UA159	54.822	100	0.548
clpP	Lactococcus lactis subsp. lactis strain DGCC12653	55.789	96.447	0.538