Detailed information    

insolico Bioinformatically predicted

Overview

Name   clpP   Type   Regulator
Locus tag   GTF74_RS04950 Genome accession   NZ_CP047303
Coordinates   1041662..1042288 (+) Length   208 a.a.
NCBI ID   WP_000121678.1    Uniprot ID   A0AAW4GZF5
Organism   Vibrio cholerae O1 biovar El Tor strain E7946     
Function   degradation of ComK; degradation of DegU (predicted from homology)   
Competence regulation

Genomic Context

Location: 1036662..1047288
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  GTF74_RS04935 (GTF74_04935) - 1037963..1039756 (-) 1794 WP_001139306.1 sensor histidine kinase -
  GTF74_RS04940 (GTF74_04940) - 1039746..1039964 (+) 219 WP_001881672.1 hypothetical protein -
  GTF74_RS04945 (GTF74_04945) tig 1040255..1041556 (+) 1302 WP_001198446.1 trigger factor -
  GTF74_RS04950 (GTF74_04950) clpP 1041662..1042288 (+) 627 WP_000121678.1 ATP-dependent Clp endopeptidase proteolytic subunit ClpP Regulator
  GTF74_RS04955 (GTF74_04955) clpX 1042368..1043648 (+) 1281 WP_000130332.1 ATP-dependent protease ATP-binding subunit ClpX Regulator
  GTF74_RS04960 (GTF74_04960) lon 1043771..1046131 (+) 2361 WP_001047611.1 endopeptidase La -
  GTF74_RS04965 (GTF74_04965) - 1046315..1046587 (+) 273 WP_001044516.1 HU family DNA-binding protein -

Sequence

Protein


Download         Length: 208 a.a.        Molecular weight: 23082.42 Da        Isoelectric Point: 5.0426

>NTDB_id=358961 GTF74_RS04950 WP_000121678.1 1041662..1042288(+) (clpP) [Vibrio cholerae O1 biovar El Tor strain E7946]
MSYQEKNAMSPIFDALVPMVVEQTSRGERSYDIYSRLLKERVIFLTGQVEDHMANLVVAQLLFLESENPDKDIFLYINSP
GGSVTAGMSIYDTMQFIKPNVSTVCMGQACSMGAFLLAGGAPGKRYVLPNSRVMIHQPLGGFQGQASDIQIHAQEILTIK
NKLNRLLAEHTGQPIEVIERDTDRDNFMSADQAVEYGLVDAVLKHRGE

Nucleotide


Download         Length: 627 bp        

>NTDB_id=358961 GTF74_RS04950 WP_000121678.1 1041662..1042288(+) (clpP) [Vibrio cholerae O1 biovar El Tor strain E7946]
ATGAGCTACCAAGAAAAAAATGCAATGTCGCCCATTTTTGACGCACTCGTACCTATGGTGGTTGAACAAACCTCTCGTGG
TGAGCGTTCATACGACATCTATTCTCGCTTACTAAAAGAACGAGTGATTTTCTTAACCGGGCAAGTAGAAGATCACATGG
CAAACCTTGTCGTGGCTCAACTGCTTTTCTTAGAATCTGAAAACCCTGATAAAGATATTTTCCTTTACATCAACTCACCC
GGTGGCAGTGTCACTGCAGGGATGTCGATTTACGATACTATGCAGTTCATCAAGCCAAACGTGAGCACAGTGTGTATGGG
ACAAGCCTGTTCAATGGGCGCTTTCTTGCTTGCTGGTGGTGCACCGGGCAAGCGTTATGTACTGCCGAATTCTCGTGTCA
TGATTCACCAACCACTGGGTGGATTCCAAGGCCAAGCCTCTGATATTCAAATTCATGCTCAAGAAATTCTGACCATTAAA
AACAAACTGAACCGTTTGTTGGCAGAGCATACAGGCCAGCCAATCGAAGTGATTGAACGCGATACTGATCGTGATAACTT
CATGTCGGCAGATCAAGCAGTGGAATACGGTTTGGTGGATGCGGTGCTGAAACACCGTGGCGAGTAA

Domains

Predicted by InterProScan.

Clp protease (CLP_protease)

(26-205)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0AAW4GZF5

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  clpP Bacillus subtilis subsp. subtilis str. 168

68.947

91.346

0.63
  clpP Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819

63.684

91.346

0.582
  clpP Streptococcus pneumoniae Rx1

54.167

92.308

0.5
  clpP Streptococcus pneumoniae D39

54.167

92.308

0.5
  clpP Streptococcus pneumoniae R6

54.167

92.308

0.5
  clpP Streptococcus pneumoniae TIGR4

54.167

92.308

0.5
  clpP Streptococcus thermophilus LMG 18311

53.125

92.308

0.49
  clpP Streptococcus thermophilus LMD-9

53.125

92.308

0.49
  clpP Streptococcus mutans UA159

51.813

92.788

0.481
  clpP Lactococcus lactis subsp. cremoris KW2

51.562

92.308

0.476
  clpP Streptococcus pyogenes JRS4

51.562

92.308

0.476
  clpP Streptococcus pyogenes MGAS315

51.562

92.308

0.476
  clpP Lactococcus lactis subsp. lactis strain DGCC12653

50

92.308

0.462

Multiple sequence alignment