Detailed information NTG0358880

Bioinformatically predicted

Overview

• Name: clpP
• Type: Regulator
• Locus tag: GTF75_RS04720
• Genome accession: NZ_CP047301
• Coordinates: 1004414..1005040 (+)
• Length: 208 a.a.
• NCBI ID: WP_000121678.1
• Uniprot ID: A0AAW4GZF5
• Organism: Vibrio cholerae O1 biovar El Tor strain DRC-193A
• Function: degradation of ComK; degradation of DegU (predicted from homology) Competence regulation

Genomic Context

Location: 999414..1010040

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
GTF75_RS04705 (GTF75_04705)	-	1000715..1002508 (-)	1794	WP_001139306.1	sensor histidine kinase	-
GTF75_RS04710 (GTF75_04710)	-	1002498..1002716 (+)	219	WP_001881672.1	hypothetical protein	-
GTF75_RS04715 (GTF75_04715)	tig	1003007..1004308 (+)	1302	WP_001198446.1	trigger factor	-
GTF75_RS04720 (GTF75_04720)	clpP	1004414..1005040 (+)	627	WP_000121678.1	ATP-dependent Clp endopeptidase proteolytic subunit ClpP	Regulator
GTF75_RS04725 (GTF75_04725)	clpX	1005120..1006400 (+)	1281	WP_000130332.1	ATP-dependent protease ATP-binding subunit ClpX	Regulator
GTF75_RS04730 (GTF75_04730)	lon	1006523..1008883 (+)	2361	WP_001047611.1	endopeptidase La	-
GTF75_RS04735 (GTF75_04735)	-	1009067..1009339 (+)	273	WP_001044516.1	HU family DNA-binding protein	-

Sequence

Protein

• Length: 208 a.a.
• Molecular weight: 23082.42 Da
• Isoelectric Point: 5.0426

>NTDB_id=358880 GTF75_RS04720 WP_000121678.1 1004414..1005040(+) (clpP) [Vibrio cholerae O1 biovar El Tor strain DRC-193A]
MSYQEKNAMSPIFDALVPMVVEQTSRGERSYDIYSRLLKERVIFLTGQVEDHMANLVVAQLLFLESENPDKDIFLYINSP
GGSVTAGMSIYDTMQFIKPNVSTVCMGQACSMGAFLLAGGAPGKRYVLPNSRVMIHQPLGGFQGQASDIQIHAQEILTIK
NKLNRLLAEHTGQPIEVIERDTDRDNFMSADQAVEYGLVDAVLKHRGE

Nucleotide

• Length: 627 bp

>NTDB_id=358880 GTF75_RS04720 WP_000121678.1 1004414..1005040(+) (clpP) [Vibrio cholerae O1 biovar El Tor strain DRC-193A]
ATGAGCTACCAAGAAAAAAATGCAATGTCGCCCATTTTTGACGCACTCGTACCTATGGTGGTTGAACAAACCTCTCGTGG
TGAGCGTTCATACGACATCTATTCTCGCTTACTAAAAGAACGAGTGATTTTCTTAACCGGGCAAGTAGAAGATCACATGG
CAAACCTTGTCGTGGCTCAACTGCTTTTCTTAGAATCTGAAAACCCTGATAAAGATATTTTCCTTTACATCAACTCACCC
GGTGGCAGTGTCACTGCAGGGATGTCGATTTACGATACTATGCAGTTCATCAAGCCAAACGTGAGCACAGTGTGTATGGG
ACAAGCCTGTTCAATGGGCGCTTTCTTGCTTGCTGGTGGTGCACCGGGCAAGCGTTATGTACTGCCGAATTCTCGTGTCA
TGATTCACCAACCACTGGGTGGATTCCAAGGCCAAGCCTCTGATATTCAAATTCATGCTCAAGAAATTCTGACCATTAAA
AACAAACTGAACCGTTTGTTGGCAGAGCATACAGGCCAGCCAATCGAAGTGATTGAACGCGATACTGATCGTGATAACTT
CATGTCGGCAGATCAAGCAGTGGAATACGGTTTGGTGGATGCGGTGCTGAAACACCGTGGCGAGTAA

Domains

Predicted by InterProScan.

• Clp protease (CLP_protease) (26-205)

3D structure

• AlphaFold DB: A0AAW4GZF5

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpP	Bacillus subtilis subsp. subtilis str. 168	68.947	91.346	0.63
clpP	Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819	63.684	91.346	0.582
clpP	Streptococcus pneumoniae Rx1	54.167	92.308	0.5
clpP	Streptococcus pneumoniae D39	54.167	92.308	0.5
clpP	Streptococcus pneumoniae R6	54.167	92.308	0.5
clpP	Streptococcus pneumoniae TIGR4	54.167	92.308	0.5
clpP	Streptococcus thermophilus LMG 18311	53.125	92.308	0.49
clpP	Streptococcus thermophilus LMD-9	53.125	92.308	0.49
clpP	Streptococcus mutans UA159	51.813	92.788	0.481
clpP	Lactococcus lactis subsp. cremoris KW2	51.562	92.308	0.476
clpP	Streptococcus pyogenes JRS4	51.562	92.308	0.476
clpP	Streptococcus pyogenes MGAS315	51.562	92.308	0.476
clpP	Lactococcus lactis subsp. lactis strain DGCC12653	50	92.308	0.462