Detailed information    

insolico Bioinformatically predicted

Overview

Name   ciaR   Type   Regulator
Locus tag   E8M05_RS05875 Genome accession   NZ_CP039457
Coordinates   1106931..1107605 (-) Length   224 a.a.
NCBI ID   WP_013851854.1    Uniprot ID   A0AAW6YDN2
Organism   Streptococcus pasteurianus strain WUSP067     
Function   repress competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 1101931..1112605
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  E8M05_RS05850 (E8M05_05845) deoC 1102412..1103074 (-) 663 WP_013851852.1 deoxyribose-phosphate aldolase -
  E8M05_RS05855 (E8M05_05850) - 1103530..1104123 (-) 594 WP_048791040.1 class I SAM-dependent methyltransferase -
  E8M05_RS05860 (E8M05_05855) coaA 1104239..1105159 (+) 921 WP_048791039.1 type I pantothenate kinase -
  E8M05_RS05865 (E8M05_05860) rpsT 1105234..1105485 (+) 252 WP_003064878.1 30S ribosomal protein S20 -
  E8M05_RS05870 (E8M05_05865) ciaH 1105601..1106941 (-) 1341 WP_003064880.1 cell wall metabolism sensor histidine kinase WalK Regulator
  E8M05_RS05875 (E8M05_05870) ciaR 1106931..1107605 (-) 675 WP_013851854.1 response regulator transcription factor Regulator
  E8M05_RS05880 (E8M05_05875) - 1107798..1110341 (-) 2544 WP_048791038.1 M1 family metallopeptidase -
  E8M05_RS05885 (E8M05_05880) phoU 1110564..1111217 (-) 654 WP_136596422.1 phosphate signaling complex protein PhoU -
  E8M05_RS05890 (E8M05_05885) pstB 1111249..1112007 (-) 759 WP_013851855.1 phosphate ABC transporter ATP-binding protein PstB -

Sequence

Protein


Download         Length: 224 a.a.        Molecular weight: 25427.14 Da        Isoelectric Point: 4.3831

>NTDB_id=358793 E8M05_RS05875 WP_013851854.1 1106931..1107605(-) (ciaR) [Streptococcus pasteurianus strain WUSP067]
MIKILLVEDDLSLSNSIFDFLDDFADVMQVFDGEEGLYEAESGVYDLILLDLMLPEKDGFQVLKELREKSVSTPVLIMTA
KESLDDKGHGFELGADDYLTKPFYLEELKMRIQALLKRSGKFSDNNLSYGELTVTTSTNTTTINGKEVEMLGKEFDLLVY
FLQNQNVILPKSQIFDRIWGFDSDTTISVVEVYVSKIRKKLKGTTFAKNLQTLRSVGYILKNAE

Nucleotide


Download         Length: 675 bp        

>NTDB_id=358793 E8M05_RS05875 WP_013851854.1 1106931..1107605(-) (ciaR) [Streptococcus pasteurianus strain WUSP067]
ATGATTAAAATATTATTAGTAGAAGACGATTTGAGTTTATCTAATTCCATTTTTGATTTTTTAGACGATTTTGCTGATGT
AATGCAAGTGTTTGATGGCGAGGAAGGTTTGTATGAAGCAGAGAGTGGTGTATATGACCTTATTCTACTTGACCTAATGT
TACCTGAGAAAGATGGCTTCCAGGTTCTAAAAGAATTACGAGAAAAGTCTGTATCAACACCTGTACTTATTATGACTGCG
AAAGAAAGCCTCGACGATAAAGGACATGGATTTGAGTTGGGAGCTGATGATTATTTAACTAAACCCTTTTACCTTGAGGA
ATTAAAAATGCGTATCCAAGCTCTTTTGAAACGTTCTGGTAAGTTTAGTGATAATAATTTGTCTTATGGAGAGCTAACTG
TTACTACTTCTACTAATACAACAACTATTAATGGTAAAGAAGTGGAAATGCTTGGTAAAGAATTTGACTTGTTGGTTTAT
TTCTTACAAAATCAAAATGTTATTTTACCAAAATCACAAATTTTTGATCGTATTTGGGGCTTTGATAGTGATACAACGAT
TTCGGTTGTTGAGGTTTACGTTTCAAAAATTCGAAAAAAACTTAAAGGCACTACTTTTGCTAAAAACCTTCAGACCCTAC
GGAGTGTAGGTTATATTCTGAAAAATGCTGAATAA

Domains

Predicted by InterproScan.

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(145-220)

Response regulator receiver domain (Response_reg)

(4-112)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  ciaR Streptococcus mutans UA159

92.377

99.554

0.92
  ciaR Streptococcus pneumoniae Rx1

86.161

100

0.862
  ciaR Streptococcus pneumoniae D39

86.161

100

0.862
  ciaR Streptococcus pneumoniae R6

86.161

100

0.862
  ciaR Streptococcus pneumoniae TIGR4

86.161

100

0.862
  covR Lactococcus lactis subsp. lactis strain DGCC12653

38.667

100

0.388
  vicR Streptococcus mutans UA159

35.47

100

0.371
  micA Streptococcus pneumoniae Cp1015

35.622

100

0.371

Multiple sequence alignment