Detailed information    

insolico Bioinformatically predicted

Overview

Name   ciaH   Type   Regulator
Locus tag   E8M05_RS05870 Genome accession   NZ_CP039457
Coordinates   1105601..1106941 (-) Length   446 a.a.
NCBI ID   WP_003064880.1    Uniprot ID   A0AAW6YHF0
Organism   Streptococcus pasteurianus strain WUSP067     
Function   Required for optimal comC expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 1100601..1111941
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  E8M05_RS05845 (E8M05_05840) - 1101153..1102217 (-) 1065 WP_003064867.1 BMP family protein -
  E8M05_RS05850 (E8M05_05845) deoC 1102412..1103074 (-) 663 WP_013851852.1 deoxyribose-phosphate aldolase -
  E8M05_RS05855 (E8M05_05850) - 1103530..1104123 (-) 594 WP_048791040.1 class I SAM-dependent methyltransferase -
  E8M05_RS05860 (E8M05_05855) coaA 1104239..1105159 (+) 921 WP_048791039.1 type I pantothenate kinase -
  E8M05_RS05865 (E8M05_05860) rpsT 1105234..1105485 (+) 252 WP_003064878.1 30S ribosomal protein S20 -
  E8M05_RS05870 (E8M05_05865) ciaH 1105601..1106941 (-) 1341 WP_003064880.1 cell wall metabolism sensor histidine kinase WalK Regulator
  E8M05_RS05875 (E8M05_05870) ciaR 1106931..1107605 (-) 675 WP_013851854.1 response regulator transcription factor Regulator
  E8M05_RS05880 (E8M05_05875) - 1107798..1110341 (-) 2544 WP_048791038.1 M1 family metallopeptidase -
  E8M05_RS05885 (E8M05_05880) phoU 1110564..1111217 (-) 654 WP_136596422.1 phosphate signaling complex protein PhoU -

Sequence

Protein


Download         Length: 446 a.a.        Molecular weight: 49991.74 Da        Isoelectric Point: 5.2300

>NTDB_id=358792 E8M05_RS05870 WP_003064880.1 1105601..1106941(-) (ciaH) [Streptococcus pasteurianus strain WUSP067]
MLNKLQKKLSSGTFSHFFHFFAVFTGIFVIMTVIILQIMRYGLYSSVDTSLQNAADNADDYVARTMERSDTLQSDDSSTD
AFSGGTGSSGKAKPSTGGVGLSNVSVLLYDEDGKILNALDAFVQFGTLSTTFDEDSVGEIKEQKITTIFGQTEKYHVLAV
KVSSSEYPSIKYATFLVSVRQLDEANERYVTITITVMVIFWIISVVASVYLANWTRKPIMESYEKQKSFVENASHELRTP
LAVLQNRLESLFRRPDATILDNSESIAASLDEVRNMRILTTNLLNLARRDDGLKVELEDIQPATFNEIFENYDMIAEENG
KTFIGHNLAERPIKSDRTLLKQLMTILFDNAIKYTDDDGVIEFTVKTTDKQTILTVADNGPGISDADKVKIFDRFYRVDK
ARTRQKGGFGLGLSLAKQIVDVLKGDIQVKDNQPKGTIFEVRFNRH

Nucleotide


Download         Length: 1341 bp        

>NTDB_id=358792 E8M05_RS05870 WP_003064880.1 1105601..1106941(-) (ciaH) [Streptococcus pasteurianus strain WUSP067]
ATGCTGAATAAATTACAGAAAAAATTATCATCAGGGACATTTTCACATTTCTTTCATTTCTTTGCTGTCTTTACAGGGAT
TTTTGTCATCATGACAGTGATTATTTTGCAGATTATGCGTTATGGACTTTATTCCTCTGTTGATACGAGTTTGCAAAATG
CAGCAGACAATGCTGATGATTATGTCGCGCGAACTATGGAACGTAGTGATACTTTGCAATCGGACGATTCTTCTACGGAC
GCTTTTTCAGGAGGAACAGGTAGTTCTGGGAAAGCGAAACCTAGTACCGGCGGAGTTGGTCTAAGCAACGTTAGCGTTCT
TCTTTATGATGAAGACGGTAAAATTTTAAATGCTTTGGATGCTTTTGTTCAATTTGGAACCTTATCGACAACTTTTGATG
AAGATAGTGTCGGTGAAATCAAAGAACAGAAGATTACGACCATTTTTGGTCAAACCGAGAAATATCATGTGTTGGCTGTA
AAAGTGAGTAGTAGCGAGTATCCTAGTATAAAATACGCTACTTTCCTTGTTAGTGTTCGTCAGTTAGATGAAGCTAACGA
ACGATACGTGACAATTACGATTACTGTTATGGTTATTTTCTGGATTATTTCGGTCGTAGCAAGTGTTTATCTTGCCAATT
GGACAAGAAAACCAATTATGGAAAGCTATGAAAAACAAAAATCCTTTGTCGAAAATGCTAGTCATGAGTTGCGTACACCG
CTTGCTGTTTTGCAGAATCGTTTAGAAAGTCTCTTTAGGCGACCTGATGCTACAATTTTGGACAATAGTGAAAGTATTGC
TGCCAGTCTAGACGAAGTTCGAAATATGCGAATTCTGACCACAAATCTGTTAAATTTAGCACGTCGTGACGATGGTTTGA
AAGTTGAGTTAGAGGATATTCAACCAGCAACTTTCAATGAAATCTTTGAAAATTACGATATGATTGCTGAAGAAAATGGC
AAGACGTTTATCGGACATAATTTGGCAGAGCGACCAATCAAATCAGACCGTACATTGTTAAAACAACTGATGACTATCTT
ATTTGATAATGCCATAAAATACACCGACGATGATGGTGTCATTGAATTTACTGTTAAAACAACAGATAAACAAACAATTC
TGACAGTTGCTGATAACGGCCCAGGGATTAGCGACGCTGATAAAGTTAAGATTTTTGACCGTTTTTATCGTGTGGATAAA
GCACGGACACGTCAAAAAGGCGGTTTTGGTCTAGGATTGTCACTTGCTAAGCAAATTGTTGATGTTTTAAAAGGCGATAT
TCAAGTCAAAGATAACCAACCAAAAGGAACTATTTTTGAAGTTCGTTTTAATCGTCATTAA

Domains

Predicted by InterproScan.

His Kinase A (phospho-acceptor) domain (HisKA)

(227-292)

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c)

(336-443)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  ciaH Streptococcus mutans UA159

59.142

99.327

0.587
  ciaH Streptococcus pneumoniae Rx1

51.467

99.327

0.511
  ciaH Streptococcus pneumoniae D39

51.467

99.327

0.511
  ciaH Streptococcus pneumoniae R6

51.467

99.327

0.511
  ciaH Streptococcus pneumoniae TIGR4

51.467

99.327

0.511

Multiple sequence alignment