Detailed information NTG0358791

Bioinformatically predicted

Overview

• Name: dprA
• Type: Machinery gene
• Locus tag: E8M05_RS05465
• Genome accession: NZ_CP039457
• Coordinates: 1028080..1028922 (-)
• Length: 280 a.a.
• NCBI ID: WP_048791150.1
• Uniprot ID: A0AAE6YSQ4
• Organism: Streptococcus pasteurianus strain WUSP067
• Function: ssDNA binding; loading RecA onto ssDNA (predicted from homology) DNA processing

Genomic Context

Location: 1023080..1033922

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
E8M05_RS05445 (E8M05_05440)	-	1023532..1024014 (-)	483	WP_003064748.1	hypothetical protein	-
E8M05_RS05450 (E8M05_05445)	-	1024031..1024750 (-)	720	WP_082144658.1	DUF3307 domain-containing protein	-
E8M05_RS05455 (E8M05_05450)	-	1024750..1025415 (-)	666	WP_048791148.1	SatD family protein	-
E8M05_RS05460 (E8M05_05455)	topA	1025563..1027704 (-)	2142	WP_048791149.1	type I DNA topoisomerase	-
E8M05_RS05465 (E8M05_05460)	dprA	1028080..1028922 (-)	843	WP_048791150.1	DNA-processing protein DprA	Machinery gene
E8M05_RS05470 (E8M05_05465)	-	1028997..1029548 (-)	552	WP_048791151.1	sugar O-acetyltransferase	-
E8M05_RS05475 (E8M05_05470)	-	1029550..1030329 (-)	780	WP_048791152.1	ribonuclease HII	-
E8M05_RS05480 (E8M05_05475)	ylqF	1030316..1031170 (-)	855	WP_136596419.1	ribosome biogenesis GTPase YlqF	-
E8M05_RS05490 (E8M05_05485)	-	1031577..1031690 (-)	114	Protein_983	sigma-70 family RNA polymerase sigma factor	-
E8M05_RS05495 (E8M05_05490)	-	1031987..1032991 (-)	1005	WP_048791196.1	sensor histidine kinase	-
E8M05_RS05500 (E8M05_05495)	-	1032988..1033647 (-)	660	WP_048791154.1	DNA-binding response regulator	-

Sequence

Protein

• Length: 280 a.a.
• Molecular weight: 31027.06 Da
• Isoelectric Point: 8.1527

>NTDB_id=358791 E8M05_RS05465 WP_048791150.1 1028080..1028922(-) (dprA) [Streptococcus pasteurianus strain WUSP067]
MNNFELFKLKKAGLTNLNILAILDYQEKQEKSLSLRNMAVVSKCKNPILFMEKYKALDIKELRKEFNCFPSVSILDDEYP
LELKHCYNPPVLLFYQGNLELLNRPKMAVVGARTASATGTKSVQKIVQELGNHFVIVSGLARGIDTSAHLSSLKNGGASI
AVIGCGLDVYYPKENKQLQEYMVKNHLVLSEYVAGEAPLKFHFPERNRIIAGLSQGVIVVEAKLRSGSLITCERALEEGR
DVFAIPGNILDGKSDGCHHLIKEGAKCVTSGLDILSEYQI

Nucleotide

• Length: 843 bp

>NTDB_id=358791 E8M05_RS05465 WP_048791150.1 1028080..1028922(-) (dprA) [Streptococcus pasteurianus strain WUSP067]
ATGAATAATTTTGAATTGTTTAAATTAAAAAAAGCAGGATTAACAAATCTTAATATTTTAGCTATTTTGGATTATCAAGA
AAAGCAAGAGAAATCACTATCTTTGCGTAATATGGCAGTCGTCTCAAAATGTAAAAATCCTATCCTTTTTATGGAAAAAT
ACAAAGCACTGGACATCAAAGAATTGCGCAAAGAATTTAATTGTTTTCCTAGTGTTTCCATACTAGATGACGAATACCCA
TTAGAACTCAAACATTGTTATAATCCACCTGTTTTGCTGTTTTATCAAGGAAATTTAGAATTACTCAATCGCCCCAAAAT
GGCAGTAGTAGGAGCAAGAACAGCATCAGCAACAGGGACAAAATCCGTACAGAAAATTGTCCAAGAACTCGGGAATCATT
TTGTTATCGTTAGTGGGTTGGCGCGTGGCATTGATACCAGTGCGCATTTATCATCTCTAAAAAACGGTGGTGCATCGATT
GCCGTTATCGGTTGTGGACTGGACGTTTATTATCCCAAAGAAAATAAGCAGTTGCAGGAGTACATGGTTAAAAATCACCT
CGTATTAAGTGAGTACGTAGCAGGAGAAGCACCGCTGAAATTCCATTTTCCAGAGCGAAATCGTATTATTGCAGGTTTAT
CACAAGGCGTTATCGTAGTAGAAGCTAAGCTGCGCTCAGGCAGTTTGATTACGTGCGAAAGAGCATTGGAAGAAGGACGA
GACGTTTTTGCCATTCCAGGAAATATTTTAGATGGAAAATCTGATGGCTGTCATCATTTGATAAAAGAGGGCGCAAAATG
CGTCACATCAGGCTTAGATATCCTTTCGGAATATCAAATATAA

Domains

Predicted by InterproScan.

• DNA recombination-mediator protein A (DNA_processg_A) (72-269)

• DNA processing protein A sterile alpha motif domain (SAM_DprA) (1-62)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
dprA	Streptococcus mutans UA159	74.82	99.286	0.743
dprA/cilB/dalA	Streptococcus mitis NCTC 12261	64.286	100	0.643
dprA/cilB/dalA	Streptococcus pneumoniae Rx1	64.286	100	0.643
dprA/cilB/dalA	Streptococcus pneumoniae D39	64.286	100	0.643
dprA/cilB/dalA	Streptococcus pneumoniae R6	64.286	100	0.643
dprA/cilB/dalA	Streptococcus pneumoniae TIGR4	64.286	100	0.643
dprA/cilB/dalA	Streptococcus mitis SK321	64.286	100	0.643
dprA	Lactococcus lactis subsp. cremoris KW2	61.871	99.286	0.614
dprA	Legionella pneumophila strain ERS1305867	42.739	86.071	0.368
dprA	Haemophilus influenzae Rd KW20	38.258	94.286	0.361