NTDB

Overview

Name	ciaR	Type	Regulator
Locus tag	GRI05_RS04100	Genome accession	NZ_CP047248
Coordinates	828152..828823 (+)	Length	223 a.a.
NCBI ID	WP_009909965.1	Uniprot ID	-
Organism	Streptococcus suis strain LSM178
Function	repress competence development (predicted from homology) Competence regulation

Genomic Context

Location: 823152..833823

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
GRI05_RS04075 (GRI05_04165)	pstB	823531..824334 (+)	804	WP_002940866.1	phosphate ABC transporter ATP-binding protein PstB	-
GRI05_RS04080 (GRI05_04170)	pstB	824346..825104 (+)	759	WP_002937614.1	phosphate ABC transporter ATP-binding protein PstB	-
GRI05_RS04085 (GRI05_04175)	phoU	825133..825789 (+)	657	WP_012028219.1	phosphate signaling complex protein PhoU	-
GRI05_RS04090 (GRI05_04180)	-	825991..827193 (-)	1203	WP_012775158.1	IS110 family transposase	-
GRI05_RS04095 (GRI05_04185)	-	827578..827958 (+)	381	WP_012027076.1	hypothetical protein	-
GRI05_RS04100 (GRI05_04190)	ciaR	828152..828823 (+)	672	WP_009909965.1	response regulator transcription factor	Regulator
GRI05_RS04105 (GRI05_04195)	ciaH	828816..830195 (+)	1380	WP_012027074.1	sensor histidine kinase	Regulator
GRI05_RS04110 (GRI05_04200)	-	830526..831755 (+)	1230	WP_012027071.1	transglutaminase domain-containing protein	-
GRI05_RS04115 (GRI05_04205)	tnpA	832170..832684 (+)	515	Protein_762	IS200/IS605 family transposase	-
GRI05_RS04120 (GRI05_04210)	rpsT	832826..833074 (-)	249	WP_012027069.1	30S ribosomal protein S20	-

Sequence

Protein

Download Length: 223 a.a. Molecular weight: 25290.00 Da Isoelectric Point: 4.2183

                                >NTDB_id=358474 GRI05_RS04100 WP_009909965.1 828152..828823(+) (ciaR) [Streptococcus suis strain LSM178]

MIKILLVEDDLSLSNSVFDFLDDFADVMQVFDGEEGVYEAETGVYDLILLDLMLPEKDGFQVLKELREKGVTTPVLITTA

KESLEDKGHGFELGADDYLTKPFYLEELKMRIQALLKRAGKFNENTLTFGDVTVDLSTNMTMVNGEEVELLGKEFDLLVY

FLQNQNVILPKTQIFDRIWGFDSDTTISVVEVYVSKIRKKLKGTTFGENLQTLRSVGYILKNA

Nucleotide

Download Length: 672 bp

                                >NTDB_id=358474 GRI05_RS04100 WP_009909965.1 828152..828823(+) (ciaR) [Streptococcus suis strain LSM178]

ATGATTAAAATATTGTTAGTGGAAGATGATTTAAGTCTATCAAATTCTGTTTTCGATTTCTTAGATGATTTTGCGGATGT

TATGCAGGTTTTTGATGGTGAAGAGGGCGTTTATGAGGCGGAAACAGGCGTTTATGATTTGATTCTTTTGGATTTAATGT

TACCTGAAAAAGACGGCTTTCAAGTCTTGAAAGAGTTACGTGAAAAGGGGGTTACGACACCAGTTCTGATTACAACAGCC

AAGGAAAGTCTAGAGGATAAAGGCCATGGTTTTGAATTGGGGGCTGATGACTATTTGACAAAACCGTTTTATTTAGAAGA

ATTGAAGATGCGAATTCAAGCTCTATTAAAACGAGCGGGTAAGTTTAATGAAAACACACTAACCTTTGGAGATGTGACAG

TTGACCTATCTACAAATATGACGATGGTAAATGGCGAAGAAGTTGAACTGTTAGGAAAAGAATTTGATCTACTAGTTTAT

TTCTTGCAAAATCAAAATGTTATTTTGCCAAAAACACAAATTTTTGACCGTATTTGGGGCTTTGACAGTGATACTACAAT

TTCAGTAGTAGAGGTATATGTTTCTAAAATTAGGAAAAAGTTGAAAGGAACGACTTTTGGGGAAAATCTTCAAACCCTGC

GTAGTGTCGGGTACATTCTAAAAAATGCCTAA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(4-112)

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(145-220)

Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.

3D structure

Source	ID	Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.

Visualization of predicted probability:

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	H_a-value
ciaR	Streptococcus mutans UA159	90.135	100	0.901
ciaR	Streptococcus pneumoniae Rx1	88.341	100	0.883
ciaR	Streptococcus pneumoniae D39	88.341	100	0.883
ciaR	Streptococcus pneumoniae R6	88.341	100	0.883
ciaR	Streptococcus pneumoniae TIGR4	88.341	100	0.883
covR	Lactococcus lactis subsp. lactis strain DGCC12653	38.496	100	0.39
vicR	Streptococcus mutans UA159	35.47	100	0.372
covR	Streptococcus salivarius strain HSISS4	35.841	100	0.363

Detailed information NTG0358474