Detailed information    

insolico Bioinformatically predicted

Overview

Name   ciaH   Type   Regulator
Locus tag   GRI05_RS04105 Genome accession   NZ_CP047248
Coordinates   828816..830195 (+) Length   459 a.a.
NCBI ID   WP_012027074.1    Uniprot ID   -
Organism   Streptococcus suis strain LSM178     
Function   repress competence development; post-transcriptional repression of CSP production (predicted from homology)   
Competence regulation

Genomic Context

Location: 823816..835195
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  GRI05_RS04080 (GRI05_04170) pstB 824346..825104 (+) 759 WP_002937614.1 phosphate ABC transporter ATP-binding protein PstB -
  GRI05_RS04085 (GRI05_04175) phoU 825133..825789 (+) 657 WP_012028219.1 phosphate signaling complex protein PhoU -
  GRI05_RS04090 (GRI05_04180) - 825991..827193 (-) 1203 WP_012775158.1 IS110 family transposase -
  GRI05_RS04095 (GRI05_04185) - 827578..827958 (+) 381 WP_012027076.1 hypothetical protein -
  GRI05_RS04100 (GRI05_04190) ciaR 828152..828823 (+) 672 WP_009909965.1 response regulator transcription factor Regulator
  GRI05_RS04105 (GRI05_04195) ciaH 828816..830195 (+) 1380 WP_012027074.1 sensor histidine kinase Regulator
  GRI05_RS04110 (GRI05_04200) - 830526..831755 (+) 1230 WP_012027071.1 transglutaminase domain-containing protein -
  GRI05_RS04115 (GRI05_04205) tnpA 832170..832684 (+) 515 Protein_762 IS200/IS605 family transposase -
  GRI05_RS04120 (GRI05_04210) rpsT 832826..833074 (-) 249 WP_012027069.1 30S ribosomal protein S20 -
  GRI05_RS04125 (GRI05_04215) coaA 833133..834053 (-) 921 WP_012027068.1 type I pantothenate kinase -
  GRI05_RS04130 (GRI05_04220) - 834162..834752 (+) 591 WP_012027067.1 class I SAM-dependent methyltransferase -

Sequence

Protein


Download         Length: 459 a.a.        Molecular weight: 51955.61 Da        Isoelectric Point: 5.5984

>NTDB_id=358475 GRI05_RS04105 WP_012027074.1 828816..830195(+) (ciaH) [Streptococcus suis strain LSM178]
MPKRIGKLVYTDKFSFFIRYFAVFTLIFGLMTAIIFQLMRSTMYQNSDNTLKRIKEEPAMAVGFAIARTYEPNSVFILQD
SPTSEETTSSSSDSMPVPKEQKNTRDGDQLRLGVNTHVLLYSKSGEMVNPDTFTGLANLPLDKEKLGEIKETTVESSFGM
SEDYRYITIGLATDELGYYSSYDIKYATILVNVSQIKSSIESYESTVAIVMVSAWLISILASIYLSNLSMRPILISYQKQ
KDFVENASHELRTPLAVLQNRLESLFRHPETTILESSESIGSSLEEVRNMRLLTTNLLNLARRDDGLKVDMIDVQPNYFD
EIFANYLMIAEENGKTLTVNNLIHQPIRTDKVLIKQLLTILFDNAMKYTDDDGTIQIAANIKDKLVCFTVIDNGLGISDV
DKKKIFDRFYRVDKARTRQKGGFGLGLSLAQQIIKNLDGEISVRDNQPKGTIFEVRLPK

Nucleotide


Download         Length: 1380 bp        

>NTDB_id=358475 GRI05_RS04105 WP_012027074.1 828816..830195(+) (ciaH) [Streptococcus suis strain LSM178]
ATGCCTAAGCGAATCGGAAAATTAGTGTATACGGATAAATTTTCCTTCTTTATCCGTTATTTTGCAGTATTTACCCTGAT
TTTTGGCTTGATGACAGCTATCATTTTTCAATTAATGCGTTCAACTATGTATCAAAATTCAGATAATACCTTGAAACGGA
TTAAGGAAGAACCAGCGATGGCTGTTGGTTTTGCGATCGCAAGAACCTATGAGCCCAACTCTGTCTTTATACTTCAAGAT
AGCCCAACTAGTGAAGAAACGACGAGCTCTAGCTCAGATAGCATGCCTGTTCCTAAAGAACAAAAAAATACTAGAGATGG
AGATCAGCTGAGATTAGGTGTCAATACTCATGTCTTACTCTATAGTAAAAGTGGAGAAATGGTCAATCCGGATACTTTTA
CTGGTTTGGCCAACCTACCGTTAGATAAGGAAAAATTGGGTGAAATTAAGGAAACTACGGTTGAATCAAGTTTTGGTATG
TCTGAAGATTATCGCTATATAACGATTGGGCTGGCTACAGATGAACTAGGTTATTATTCGTCCTATGATATAAAATATGC
GACAATTTTGGTGAATGTCAGCCAAATTAAATCTTCCATTGAGAGCTATGAATCGACAGTTGCTATTGTTATGGTATCAG
CTTGGTTGATTTCTATACTAGCAAGTATTTACCTATCGAATCTTAGCATGCGTCCAATCCTAATTAGTTATCAAAAACAA
AAAGACTTCGTTGAAAATGCTAGTCATGAGTTACGCACACCGTTGGCAGTTCTTCAAAATCGCCTGGAAAGTCTATTTCG
TCATCCCGAGACAACTATTTTGGAAAGTAGTGAAAGCATCGGATCTAGTTTAGAAGAAGTTCGAAATATGCGACTATTAA
CAACGAACTTGCTCAATTTGGCTCGTCGTGATGATGGCTTAAAAGTCGATATGATCGATGTCCAACCCAACTATTTTGAT
GAAATCTTTGCTAATTACCTTATGATTGCCGAAGAAAATGGAAAAACTCTAACAGTTAATAATTTGATTCATCAGCCAAT
TCGAACAGACAAGGTTTTGATTAAACAGTTGCTCACCATTTTGTTTGACAACGCTATGAAGTATACCGATGATGATGGGA
CAATTCAAATAGCAGCTAATATCAAGGACAAACTAGTTTGTTTTACAGTTATTGACAATGGTTTGGGAATCAGCGATGTC
GATAAAAAGAAAATCTTTGATCGCTTTTACCGAGTTGACAAGGCTAGAACACGTCAAAAAGGTGGATTTGGTTTAGGTTT
ATCTTTAGCTCAACAAATTATTAAGAATCTAGATGGTGAGATTTCTGTGAGAGATAACCAACCGAAAGGAACTATTTTTG
AGGTACGTTTACCCAAATAA

Domains

Predicted by InterProScan.

His Kinase A (phospho-acceptor) domain (HisKA)

(240-306)

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c)

(350-458)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  ciaH Streptococcus pneumoniae Rx1

49.237

100

0.492
  ciaH Streptococcus pneumoniae D39

49.237

100

0.492
  ciaH Streptococcus pneumoniae R6

49.237

100

0.492
  ciaH Streptococcus pneumoniae TIGR4

49.237

100

0.492
  ciaH Streptococcus mutans UA159

49.664

97.386

0.484