Detailed information NTG0357290

Bioinformatically predicted

Overview

• Name: braR
• Type: Regulator
• Locus tag: E1949_RS06620
• Genome accession: NZ_CP039160
• Coordinates: 1316308..1316982 (-)
• Length: 224 a.a.
• NCBI ID: WP_000866106.1
• Uniprot ID: -
• Organism: Staphylococcus aureus strain Lr6
• Function: promote expression of competence genes (predicted from homology) Competence regulation

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type	MGE coordinates	Gene coordinates	Relative position	Distance (bp)
IScluster/Tn	1310539..1320734	1316308..1316982	within	0

Gene organization within MGE regions

Location: 1310539..1320734

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
E1949_RS06580 (E1949_06705)	aph(3')-IIIa	1310539..1311333 (-)	795	WP_001096887.1	aminoglycoside O-phosphotransferase APH(3')-IIIa	-
E1949_RS06585 (E1949_06710)	sat4	1311426..1311961 (-)	536	Protein_1267	streptothricin N-acetyltransferase Sat4	-
E1949_RS06590 (E1949_06715)	-	1311958..1312593 (-)	636	Protein_1268	aminoglycoside 6-adenylyltransferase	-
E1949_RS06595 (E1949_06720)	-	1312734..1313408 (-)	675	WP_001105960.1	IS6 family transposase	-
E1949_RS06600 (E1949_06725)	-	1313465..1313641 (-)	177	Protein_1270	undecaprenyl-diphosphate phosphatase	-
E1949_RS06605 (E1949_06730)	-	1313655..1314392 (-)	738	WP_138079897.1	ABC transporter permease	-
E1949_RS06610 (E1949_06735)	-	1314385..1315314 (-)	930	WP_000793446.1	ABC transporter ATP-binding protein	-
E1949_RS06615 (E1949_06740)	-	1315430..1316311 (-)	882	Protein_1273	sensor histidine kinase	-
E1949_RS06620 (E1949_06745)	braR	1316308..1316982 (-)	675	WP_000866106.1	response regulator transcription factor	Regulator
E1949_RS06625 (E1949_06750)	-	1317122..1317796 (-)	675	WP_001105960.1	IS6 family transposase	-
E1949_RS06630 (E1949_06755)	msr(A)	1318270..1319736 (+)	1467	WP_000438874.1	ABC-F type ribosomal protection protein Msr(A)	-
E1949_RS06635 (E1949_06760)	-	1319835..1320734 (+)	900	WP_000196697.1	Mph(C) family macrolide 2'-phosphotransferase	-

Sequence

Protein

• Length: 224 a.a.
• Molecular weight: 25839.93 Da
• Isoelectric Point: 4.9884

>NTDB_id=357290 E1949_RS06620 WP_000866106.1 1316308..1316982(-) (braR) [Staphylococcus aureus strain Lr6]
MKVLIVEDDLVIGKMLAEELKKWQLEPILIEGFNHVMDAFNTNAPELVLLDINLPAFNGYHWCQEIRKVSTVPIIFISSR
NDSMDQVMAMQMGADDFIEKPFNMTVTITKIQALLRRTYDFTTQVNNLTVDDCELLLDAAKLKFNEETIDLTHTELQIMH
SLFQNKGKFVSRNALIEKCWESEHFIDDNTLAVNITRLRKKLQKLGLTDFIETKKNVGYRVGDV

Nucleotide

• Length: 675 bp

>NTDB_id=357290 E1949_RS06620 WP_000866106.1 1316308..1316982(-) (braR) [Staphylococcus aureus strain Lr6]
ATGAAAGTATTAATCGTAGAGGATGACTTAGTTATCGGGAAGATGCTTGCTGAAGAGCTCAAGAAGTGGCAGCTAGAACC
GATCTTAATAGAAGGTTTCAATCATGTAATGGATGCCTTCAACACGAATGCACCGGAACTTGTGTTACTCGATATTAATT
TACCTGCCTTCAATGGTTATCACTGGTGTCAGGAGATTCGTAAAGTTTCTACTGTACCGATTATATTTATTAGTTCGCGT
AACGACAGTATGGATCAAGTAATGGCGATGCAGATGGGTGCGGATGATTTCATTGAGAAGCCATTTAATATGACTGTTAC
AATTACTAAGATTCAAGCACTATTACGCCGCACGTATGATTTCACCACTCAAGTTAATAATTTAACAGTAGATGATTGCG
AGTTACTACTTGATGCAGCAAAGCTTAAATTTAATGAAGAAACCATAGACCTGACACACACTGAATTGCAAATCATGCAT
AGCTTATTCCAGAACAAGGGCAAATTCGTCAGTCGTAATGCGTTAATCGAAAAATGCTGGGAATCAGAACACTTCATTGA
TGACAATACGCTTGCTGTCAACATTACACGTTTACGCAAAAAGCTACAAAAACTAGGACTTACAGATTTTATCGAAACGA
AGAAAAATGTCGGATATCGTGTAGGTGACGTATGA

Domains

Predicted by InterproScan.

• Transcriptional regulatory protein, C terminal (Trans_reg_C) (147-220)

• Response regulator receiver domain (Response_reg) (3-111)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
braR	Staphylococcus aureus N315	66.516	98.661	0.656