Detailed information    

insolico Bioinformatically predicted

Overview

Name   vicR   Type   Regulator
Locus tag   E3C75_RS08305 Genome accession   NZ_CP038020
Coordinates   1569065..1569772 (-) Length   235 a.a.
NCBI ID   WP_011681206.1    Uniprot ID   -
Organism   Streptococcus thermophilus strain ATCC 19258     
Function   repress comCDE expression; repress comX expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 1564065..1574772
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  E3C75_RS08280 yidA 1564408..1565217 (+) 810 WP_011226081.1 sugar-phosphatase -
  E3C75_RS08285 - 1565219..1566433 (+) 1215 WP_084830670.1 aminoacyltransferase -
  E3C75_RS08290 - 1566485..1566846 (-) 362 Protein_1588 YbaN family protein -
  E3C75_RS08295 vicX 1566914..1567723 (-) 810 WP_100262465.1 MBL fold metallo-hydrolase Regulator
  E3C75_RS08300 vicK 1567732..1569072 (-) 1341 WP_084828862.1 cell wall metabolism sensor histidine kinase VicK Regulator
  E3C75_RS08305 vicR 1569065..1569772 (-) 708 WP_011681206.1 response regulator YycF Regulator
  E3C75_RS08310 - 1570299..1571066 (+) 768 WP_011681207.1 amino acid ABC transporter ATP-binding protein -
  E3C75_RS08315 - 1571078..1571911 (+) 834 WP_002953142.1 transporter substrate-binding domain-containing protein -
  E3C75_RS08320 - 1571929..1572627 (+) 699 WP_014608374.1 amino acid ABC transporter permease -
  E3C75_RS08325 - 1572639..1573289 (+) 651 WP_100273221.1 amino acid ABC transporter permease -
  E3C75_RS08330 endA 1573360..1574241 (-) 882 WP_111679622.1 DNA/RNA non-specific endonuclease Machinery gene
  E3C75_RS08335 - 1574303..1574491 (-) 189 WP_011226090.1 DNA-directed RNA polymerase subunit beta -

Sequence

Protein


Download         Length: 235 a.a.        Molecular weight: 27058.98 Da        Isoelectric Point: 5.0130

>NTDB_id=351421 E3C75_RS08305 WP_011681206.1 1569065..1569772(-) (vicR) [Streptococcus thermophilus strain ATCC 19258]
MKKILVVDDERPISDIIKFNLTKEGYEVVTAFDGREALEQFEAKKPDLVILDLMLPELDGLEVAKEIRKTSHTPIIMLSA
KDSEFDKVIGLEIGADDYVTKPFSNRELLARIKAHLRRTETIETAVEESSNSGKQEISIGELVIVPDAFVAKKRGNEVEL
THREFELLFHLATHMGQVMTREHLLETVWGYDYFGDVRTVDVTIRRLREKIEDTPSRPEYILTRRGVGYYMKNYD

Nucleotide


Download         Length: 708 bp        

>NTDB_id=351421 E3C75_RS08305 WP_011681206.1 1569065..1569772(-) (vicR) [Streptococcus thermophilus strain ATCC 19258]
ATGAAAAAAATTCTAGTTGTTGATGATGAAAGACCAATCTCCGATATCATCAAGTTTAACCTTACTAAGGAGGGTTATGA
AGTGGTTACGGCCTTTGATGGGCGAGAAGCTTTGGAACAATTTGAAGCTAAAAAACCAGACTTGGTTATTCTGGACTTGA
TGTTGCCTGAACTGGATGGTTTGGAAGTTGCCAAGGAAATCCGTAAAACGAGCCACACACCGATTATCATGCTTTCAGCT
AAAGATAGTGAGTTTGATAAGGTTATCGGATTAGAAATTGGGGCAGACGACTATGTGACTAAGCCATTTTCTAACCGTGA
ATTGTTGGCACGTATTAAAGCCCACTTGCGTCGTACAGAAACGATTGAAACTGCAGTAGAAGAGAGCTCTAACTCTGGCA
AACAAGAAATTTCAATTGGTGAGTTGGTTATTGTTCCGGATGCCTTTGTTGCTAAAAAACGTGGAAACGAAGTTGAGTTG
ACCCACCGTGAATTTGAGTTACTCTTCCATTTGGCAACTCATATGGGACAAGTTATGACGCGTGAACATTTGCTTGAAAC
CGTTTGGGGCTATGACTATTTTGGGGATGTTCGTACTGTGGACGTAACGATTCGTCGTCTGCGTGAAAAAATTGAAGATA
CACCTAGCCGTCCTGAATATATCTTGACGCGTCGTGGTGTCGGTTATTACATGAAGAATTATGACTAG

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(4-113)

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(155-230)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vicR Streptococcus mutans UA159

85.532

100

0.855
  micA Streptococcus pneumoniae Cp1015

80.258

99.149

0.796
  covR Lactococcus lactis subsp. lactis strain DGCC12653

46.32

98.298

0.455
  covR Streptococcus salivarius strain HSISS4

45.299

99.574

0.451
  scnR Streptococcus mutans UA159

38.559

100

0.387

Multiple sequence alignment