Detailed information    

insolico Bioinformatically predicted

Overview

Name   endA   Type   Machinery gene
Locus tag   E3C75_RS08330 Genome accession   NZ_CP038020
Coordinates   1573360..1574241 (-) Length   293 a.a.
NCBI ID   WP_111679622.1    Uniprot ID   -
Organism   Streptococcus thermophilus strain ATCC 19258     
Function   cleavage of dsDNA into ssDNA (predicted from homology)   
DNA processing

Genomic Context

Location: 1568360..1579241
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  E3C75_RS08305 vicR 1569065..1569772 (-) 708 WP_011681206.1 response regulator YycF Regulator
  E3C75_RS08310 - 1570299..1571066 (+) 768 WP_011681207.1 amino acid ABC transporter ATP-binding protein -
  E3C75_RS08315 - 1571078..1571911 (+) 834 WP_002953142.1 transporter substrate-binding domain-containing protein -
  E3C75_RS08320 - 1571929..1572627 (+) 699 WP_014608374.1 amino acid ABC transporter permease -
  E3C75_RS08325 - 1572639..1573289 (+) 651 WP_100273221.1 amino acid ABC transporter permease -
  E3C75_RS08330 endA 1573360..1574241 (-) 882 WP_111679622.1 DNA/RNA non-specific endonuclease Machinery gene
  E3C75_RS08335 - 1574303..1574491 (-) 189 WP_011226090.1 DNA-directed RNA polymerase subunit beta -
  E3C75_RS08340 murA 1574493..1575764 (-) 1272 WP_024704149.1 UDP-N-acetylglucosamine 1-carboxyvinyltransferase -
  E3C75_RS08345 - 1575834..1576070 (-) 237 WP_002946959.1 DUF1146 family protein -
  E3C75_RS08350 galE 1576258..1577271 (-) 1014 WP_014621668.1 UDP-glucose 4-epimerase GalE -
  E3C75_RS11745 - 1577286..1578098 (-) 813 WP_223899678.1 hypothetical protein -

Sequence

Protein


Download         Length: 293 a.a.        Molecular weight: 31789.50 Da        Isoelectric Point: 10.1789

>NTDB_id=351422 E3C75_RS08330 WP_111679622.1 1573360..1574241(-) (endA) [Streptococcus thermophilus strain ATCC 19258]
MAKRKTSLTNKQKRQLVTLIIAALIAVLGYLGTSNKLSPDNPIRQVASLVSGKSNKSIKSNGSTNSQSTPQEQLSETVMT
SSVKSQLGNSLEWNGAGAYIINRNKTNLNAKVSSQPYANNQVKTVQGQTVPTVANALLSKATRQYKNRQETGNGSTSWTP
AGWHQVQNLSGEYSHAVDRGHLLGYALIGGLKGFDASTSNPENIAVQTAWANQAYSDSSTGQNYYESLVRKALDKNKRVR
YRVTLIYEGENLIPSGTHLEAKSADGSLEFNVFVPNVQEGITLDYYSGKVTVN

Nucleotide


Download         Length: 882 bp        

>NTDB_id=351422 E3C75_RS08330 WP_111679622.1 1573360..1574241(-) (endA) [Streptococcus thermophilus strain ATCC 19258]
ATGGCAAAAAGAAAGACATCTTTGACAAATAAACAGAAACGTCAGTTAGTCACATTAATAATAGCAGCTTTAATAGCTGT
TTTAGGTTACCTAGGAACCAGTAACAAGCTCTCGCCTGATAATCCTATCAGACAAGTAGCAAGTCTAGTTTCAGGGAAAT
CTAACAAATCCATTAAATCTAATGGTTCAACAAATAGTCAGTCTACACCACAAGAGCAGCTTTCTGAGACAGTAATGACT
AGTTCAGTCAAAAGCCAACTGGGTAATTCCTTGGAATGGAATGGAGCTGGGGCCTACATTATTAATAGAAATAAGACGAA
TCTAAATGCTAAGGTATCAAGCCAACCCTATGCTAATAACCAAGTCAAAACGGTTCAAGGACAAACTGTTCCTACAGTTG
CTAATGCCTTATTAAGTAAAGCAACTAGACAGTACAAAAATCGTCAAGAAACAGGGAATGGTTCAACCTCTTGGACACCA
GCTGGATGGCACCAGGTTCAAAATTTATCAGGAGAGTATAGCCATGCCGTAGATAGAGGCCATTTGCTAGGTTATGCACT
GATAGGTGGTTTGAAAGGATTTGACGCCTCGACTTCAAATCCAGAGAATATTGCTGTTCAAACTGCTTGGGCAAATCAAG
CATATAGCGATAGTTCTACAGGCCAAAACTATTATGAAAGCCTAGTACGAAAAGCTCTGGATAAAAACAAACGTGTTCGT
TATCGTGTGACCCTGATTTATGAAGGAGAGAATCTCATTCCATCAGGAACACATCTTGAAGCTAAGTCAGCAGACGGCTC
ACTTGAGTTTAATGTCTTTGTTCCAAATGTACAAGAGGGAATTACACTAGATTACTATTCAGGAAAAGTAACGGTGAATT
GA

Domains

Predicted by InterproScan.

DNA/RNA non-specific endonuclease (Endonuclease_NS)

(101-266)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  endA Streptococcus pneumoniae Rx1

72.385

81.57

0.59
  endA Streptococcus pneumoniae D39

72.385

81.57

0.59
  endA Streptococcus pneumoniae R6

72.385

81.57

0.59
  endA Streptococcus pneumoniae TIGR4

72.385

81.57

0.59

Multiple sequence alignment