Detailed information    

insolico Bioinformatically predicted

Overview

Name   vicK   Type   Regulator
Locus tag   E3C75_RS08300 Genome accession   NZ_CP038020
Coordinates   1567732..1569072 (-) Length   446 a.a.
NCBI ID   WP_084828862.1    Uniprot ID   A0A0E2Q0P2
Organism   Streptococcus thermophilus strain ATCC 19258     
Function   repress comCDE expression; repress comX expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 1562732..1574072
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  E3C75_RS08270 - 1562842..1563228 (-) 387 WP_084828860.1 DUF1934 domain-containing protein -
  E3C75_RS08275 - 1563286..1564200 (-) 915 Protein_1585 GNAT family N-acetyltransferase -
  E3C75_RS08280 yidA 1564408..1565217 (+) 810 WP_011226081.1 sugar-phosphatase -
  E3C75_RS08285 - 1565219..1566433 (+) 1215 WP_084830670.1 aminoacyltransferase -
  E3C75_RS08290 - 1566485..1566846 (-) 362 Protein_1588 YbaN family protein -
  E3C75_RS08295 vicX 1566914..1567723 (-) 810 WP_100262465.1 MBL fold metallo-hydrolase Regulator
  E3C75_RS08300 vicK 1567732..1569072 (-) 1341 WP_084828862.1 cell wall metabolism sensor histidine kinase VicK Regulator
  E3C75_RS08305 vicR 1569065..1569772 (-) 708 WP_011681206.1 response regulator YycF Regulator
  E3C75_RS08310 - 1570299..1571066 (+) 768 WP_011681207.1 amino acid ABC transporter ATP-binding protein -
  E3C75_RS08315 - 1571078..1571911 (+) 834 WP_002953142.1 transporter substrate-binding domain-containing protein -
  E3C75_RS08320 - 1571929..1572627 (+) 699 WP_014608374.1 amino acid ABC transporter permease -
  E3C75_RS08325 - 1572639..1573289 (+) 651 WP_100273221.1 amino acid ABC transporter permease -

Sequence

Protein


Download         Length: 446 a.a.        Molecular weight: 50777.01 Da        Isoelectric Point: 5.2465

>NTDB_id=351420 E3C75_RS08300 WP_084828862.1 1567732..1569072(-) (vicK) [Streptococcus thermophilus strain ATCC 19258]
MTSIGLNITSFELALLFTLLFVAFYFIFLAYRDYQQVKNIRKLTKRVKSLMAGNYNEKLRIKGDSELLELANSLNDLSDV
FRLTHENLIQEKNRLSSVLSYMSDGVIATNRLGQITMINSTAQRLLNLDRETATQMSILDILDGENPYTYSELLSKTPEI
HLSRRDANDEFVTLRVNFALIRKESGFISGLVAVLHDATEQEKEERERRLFVSNVSHELRTPLTSVKSYLEALDDGALNE
EIAPNFIKVSLDETNRMMRMISDLLALSRIDNKSTQLNVEMTNFTAFMTYILNRFGQIKSQETNPGKSYEIIRDYPVNSI
WVEIDTDKMTQVVDNILNNAIKYSPDGGQITVSMKTTDTQLIVSISDQGLGIPKKDLPLIFDRFYRVDKARSRAQGGTGL
GLSIAKEIVKQHNGFIWAKSEYGKGSTFTIVLPYDQDAMMVDEWEM

Nucleotide


Download         Length: 1341 bp        

>NTDB_id=351420 E3C75_RS08300 WP_084828862.1 1567732..1569072(-) (vicK) [Streptococcus thermophilus strain ATCC 19258]
ATGACTAGTATTGGCTTAAATATTACAAGCTTTGAACTAGCCTTACTCTTTACGCTCCTCTTTGTTGCTTTCTATTTCAT
TTTTCTAGCTTATCGTGATTATCAACAGGTCAAAAATATCCGAAAGTTGACTAAGAGAGTCAAATCCCTTATGGCAGGTA
ATTATAATGAAAAATTACGCATAAAGGGAGATTCAGAGCTTTTAGAGCTAGCTAATAGCTTGAATGATTTGTCGGACGTC
TTTCGTTTGACACATGAAAATCTAATCCAGGAAAAAAACCGCTTATCATCTGTCCTTTCGTACATGAGTGACGGGGTTAT
TGCGACCAATCGCCTTGGTCAGATTACTATGATTAATAGTACTGCCCAACGCTTGTTGAATTTAGATCGCGAAACTGCGA
CTCAGATGTCTATTTTGGATATATTAGATGGTGAGAATCCCTATACCTATAGTGAATTGTTGTCTAAGACACCCGAAATC
CATCTGTCGCGTCGAGATGCTAACGATGAATTTGTGACGCTACGTGTTAATTTTGCATTAATTCGTAAGGAATCTGGTTT
TATTTCAGGTCTGGTAGCCGTTCTTCATGATGCCACTGAGCAGGAAAAAGAAGAGCGCGAACGCCGTCTCTTCGTATCAA
ATGTTAGTCACGAATTGCGGACGCCTTTAACTTCTGTGAAATCCTATCTTGAAGCGCTTGATGATGGTGCTCTCAACGAA
GAGATTGCTCCAAACTTTATCAAAGTTTCTTTAGATGAAACCAACCGCATGATGCGTATGATTTCTGACCTCTTGGCATT
ATCTCGAATTGACAATAAAAGCACACAGCTTAATGTTGAAATGACAAACTTTACAGCCTTTATGACCTATATCTTGAATC
GATTTGGTCAAATTAAGAGTCAAGAAACTAATCCAGGTAAGTCTTATGAAATCATTCGAGATTACCCAGTAAACTCTATT
TGGGTGGAAATTGATACTGATAAGATGACCCAGGTCGTAGATAATATACTTAATAATGCCATCAAGTATTCTCCTGATGG
TGGGCAAATTACAGTATCTATGAAAACGACAGACACTCAGTTGATTGTTTCTATTTCTGACCAAGGTTTAGGAATTCCTA
AAAAAGATTTACCTCTGATTTTTGACCGTTTTTACCGTGTTGATAAGGCCAGAAGTCGTGCTCAGGGTGGAACAGGACTT
GGCTTGTCCATAGCAAAAGAAATTGTTAAACAACATAATGGCTTCATTTGGGCTAAGAGTGAGTATGGTAAGGGGTCAAC
TTTTACAATTGTGCTTCCATATGACCAGGACGCAATGATGGTCGATGAATGGGAGATGTAG

Domains

Predicted by InterproScan.

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c)

(325-435)

PAS fold (PAS)

(94-197)

His Kinase A (phospho-acceptor) domain (HisKA)

(208-272)

HAMP domain (HAMP)

(37-79)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A0E2Q0P2

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vicK Streptococcus mutans UA159

73.913

92.825

0.686
  micB Streptococcus pneumoniae Cp1015

66.051

97.085

0.641

Multiple sequence alignment