Detailed information NTG0351403

Bioinformatically predicted

Overview

• Name: clpP
• Type: Regulator
• Locus tag: E3C75_RS04065
• Genome accession: NZ_CP038020
• Coordinates: 766660..767250 (+)
• Length: 196 a.a.
• NCBI ID: WP_084828504.1
• Uniprot ID: A0A0E2QJQ9
• Organism: Streptococcus thermophilus strain ATCC 19258
• Function: degradation of ComX (predicted from homology) Competence regulation

Genomic Context

Location: 761660..772250

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
E3C75_RS04035	-	762037..762656 (+)	620	Protein_754	cation-translocating P-type ATPase C-terminal domain-containing protein	-
E3C75_RS04040	-	762936..764030 (+)	1095	WP_084828500.1	cystathionine gamma-synthase	-
E3C75_RS04045	-	764041..765204 (+)	1164	WP_084828501.1	MalY/PatB family protein	-
E3C75_RS04050	-	765280..765447 (+)	168	WP_084828502.1	levansucrase	-
E3C75_RS04055	-	765488..765763 (+)	276	WP_084828503.1	hypothetical protein	-
E3C75_RS04060	upp	765893..766522 (+)	630	WP_002946740.1	uracil phosphoribosyltransferase	-
E3C75_RS04065	clpP	766660..767250 (+)	591	WP_084828504.1	ATP-dependent Clp protease proteolytic subunit	Regulator
E3C75_RS04070	-	767337..767786 (+)	450	WP_084828505.1	YlbF family regulator	-
E3C75_RS04075	-	767779..768060 (+)	282	WP_002949736.1	YlbG family protein	-
E3C75_RS04080	-	768217..769392 (+)	1176	WP_100262554.1	ABC transporter substrate-binding protein	-
E3C75_RS04085	-	769436..770320 (+)	885	WP_011225509.1	branched-chain amino acid ABC transporter permease	-
E3C75_RS04090	-	770324..771274 (+)	951	WP_011225510.1	branched-chain amino acid ABC transporter permease	-
E3C75_RS04095	-	771277..772041 (+)	765	WP_111679257.1	ABC transporter ATP-binding protein	-

Sequence

Protein

• Length: 196 a.a.
• Molecular weight: 21600.66 Da
• Isoelectric Point: 4.5831

>NTDB_id=351403 E3C75_RS04065 WP_084828504.1 766660..767250(+) (clpP) [Streptococcus thermophilus strain ATCC 19258]
MIPVVIEQTSRGERSYDIYSRLLKDRIIMLTGPIEDNMANSIIAQLLFLDAQDHTKDIYLYVNTPGGSVSAGLAIVDTMN
FIKSDVQTIVMGMAASMGTIIASSGTKGKRFMLPNAEYMIHQPMGGTGGGTQQTDMAIAAEHLLKTRNNLEQILADNSGQ
PIEKVHVDAERDNWMSAQETLEYGFIDEIMTNNQLK

Nucleotide

• Length: 591 bp

>NTDB_id=351403 E3C75_RS04065 WP_084828504.1 766660..767250(+) (clpP) [Streptococcus thermophilus strain ATCC 19258]
ATGATTCCGGTAGTTATTGAACAAACATCACGTGGTGAACGTTCTTATGACATTTACTCACGTTTGCTCAAGGATCGTAT
TATCATGTTAACAGGTCCTATAGAAGATAATATGGCAAACTCAATTATCGCTCAACTCTTGTTCTTGGATGCTCAAGACC
ATACAAAAGATATCTATCTGTATGTTAATACACCTGGTGGGTCAGTTTCAGCAGGCCTTGCCATTGTTGATACAATGAAC
TTCATCAAGTCTGATGTTCAAACCATCGTTATGGGGATGGCAGCATCAATGGGTACAATTATCGCTTCAAGCGGTACCAA
AGGTAAACGTTTCATGTTGCCAAATGCAGAATACATGATTCACCAACCAATGGGTGGTACTGGTGGTGGTACTCAACAAA
CAGATATGGCTATCGCTGCTGAACACTTGCTCAAGACTCGTAATAACTTGGAGCAAATCTTGGCTGATAATTCTGGTCAG
CCAATTGAAAAGGTTCATGTCGATGCTGAACGTGATAATTGGATGAGTGCCCAAGAAACACTTGAATATGGCTTCATTGA
TGAAATCATGACCAACAACCAATTAAAATAA

Domains

Predicted by InterproScan.

• Clp protease (CLP_protease) (11-192)

3D structure

• AlphaFold DB: A0A0E2QJQ9

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpP	Streptococcus thermophilus LMG 18311	99.49	100	0.995
clpP	Streptococcus thermophilus LMD-9	99.49	100	0.995
clpP	Streptococcus pneumoniae Rx1	92.821	99.49	0.923
clpP	Streptococcus pneumoniae D39	92.821	99.49	0.923
clpP	Streptococcus pneumoniae R6	92.821	99.49	0.923
clpP	Streptococcus pneumoniae TIGR4	92.821	99.49	0.923
clpP	Streptococcus pyogenes JRS4	89.286	100	0.893
clpP	Streptococcus pyogenes MGAS315	89.286	100	0.893
clpP	Streptococcus mutans UA159	87.245	100	0.872
clpP	Lactococcus lactis subsp. lactis strain DGCC12653	86.735	100	0.867
clpP	Lactococcus lactis subsp. cremoris KW2	86.224	100	0.862
clpP	Bacillus subtilis subsp. subtilis str. 168	59.184	100	0.592
clpP	Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819	58.549	98.469	0.577