Detailed information NTG0351398

Bioinformatically predicted

Overview

• Name: comR
• Type: Regulator
• Locus tag: E3C75_RS03665
• Genome accession: NZ_CP038020
• Coordinates: 689406..690305 (+)
• Length: 299 a.a.
• NCBI ID: WP_111679231.1
• Uniprot ID: -
• Organism: Streptococcus thermophilus strain ATCC 19258
• Function: activate transcription of comX; activate transcription of comS (predicted from homology) Competence regulation

Genomic Context

Location: 684406..695305

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
E3C75_RS03645	trkA	685543..686892 (-)	1350	WP_024704181.1	Trk system potassium transporter TrkA	-
E3C75_RS03650	-	687181..687690 (+)	510	WP_011680717.1	tRNA (cytidine(34)-2'-O)-methyltransferase	-
E3C75_RS03655	-	688001..688558 (+)	558	WP_111679227.1	ECF transporter S component	-
E3C75_RS03660	-	688561..689211 (+)	651	WP_111679229.1	phosphatase PAP2 family protein	-
E3C75_RS03665	comR	689406..690305 (+)	900	WP_111679231.1	helix-turn-helix domain-containing protein	Regulator
E3C75_RS11980	-	690543..690839 (+)	297	Protein_680	cysteine peptidase family C39 domain-containing protein	-
E3C75_RS11985	comA	691005..691400 (+)	396	WP_252989162.1	ABC transporter transmembrane domain-containing protein	Regulator
E3C75_RS11990	comA	691484..691954 (+)	471	WP_111679233.1	ABC transporter transmembrane domain-containing protein	Regulator
E3C75_RS03685	comA	692009..692578 (+)	570	WP_231907528.1	ATP-binding cassette domain-containing protein	Regulator
E3C75_RS03690	-	692708..693016 (+)	309	WP_223899647.1	DUF805 domain-containing protein	-
E3C75_RS11500	-	693162..693641 (-)	480	WP_223899648.1	DUF4153 domain-containing protein	-
E3C75_RS11505	-	694082..694453 (-)	372	WP_223899649.1	hypothetical protein	-

Sequence

Protein

• Length: 299 a.a.
• Molecular weight: 35312.78 Da
• Isoelectric Point: 5.1031

>NTDB_id=351398 E3C75_RS03665 WP_111679231.1 689406..690305(+) (comR) [Streptococcus thermophilus strain ATCC 19258]
MNIKDSIGLRIKTEREHQQMSREVLCLDGAELTVRQLIRIEKGESLPSLDRLSYIAKRLGKSMTELLDQDNITIPDEYYE
MKNRLIKFPTYRNPDRIKSKLTLIEEVYEKFFDILPEEELLTLDILENILSFTSWEESPKVEEIYEDLFEQVKRKRKFST
NDLLVIDYYFFHLYGRKQYDKKLFERIIKRVLNQEIWTDDVYNIVLFNDLMAIAALKIFHNSFSDFLTVVDKALVVIEKS
QLYSYKPSVFVLKAKYELLHKENKKEAAENYDKAIMFASVLEDSVLEESIKAGKLADGL

Nucleotide

• Length: 900 bp

>NTDB_id=351398 E3C75_RS03665 WP_111679231.1 689406..690305(+) (comR) [Streptococcus thermophilus strain ATCC 19258]
TTGAACATAAAAGACAGCATTGGACTAAGAATCAAAACTGAGCGTGAACACCAACAGATGTCACGTGAAGTGCTATGTTT
AGATGGTGCGGAATTGACTGTTCGCCAGTTAATTCGTATTGAAAAGGGGGAGTCTCTCCCGTCTTTAGATAGATTATCGT
ATATTGCTAAACGTTTAGGAAAAAGTATGACAGAGTTATTGGATCAAGACAATATTACCATTCCTGACGAATATTATGAA
ATGAAGAATCGTTTGATTAAGTTTCCAACGTACAGAAACCCTGACAGAATAAAGTCTAAACTTACTTTGATTGAGGAAGT
CTATGAGAAATTTTTTGATATTCTTCCAGAAGAAGAATTATTAACTCTAGACATTCTCGAAAATATATTGAGTTTTACTA
GTTGGGAGGAGAGTCCAAAAGTTGAGGAGATATATGAAGACTTGTTTGAACAAGTCAAAAGGAAGAGGAAATTCTCAACT
AACGATTTATTAGTCATTGACTATTATTTCTTTCATCTTTATGGCAGAAAACAGTATGACAAAAAACTATTTGAAAGAAT
TATAAAGAGAGTATTAAATCAGGAAATTTGGACAGATGATGTTTACAATATTGTTTTATTTAATGATTTGATGGCTATTG
CTGCTTTAAAGATTTTTCACAATTCCTTCTCAGACTTCTTAACAGTTGTGGATAAAGCCTTAGTTGTCATAGAAAAATCA
CAATTATATAGCTACAAGCCTAGTGTTTTTGTACTTAAGGCTAAATATGAACTTCTGCATAAAGAAAACAAGAAAGAGGC
TGCAGAGAATTATGATAAGGCCATAATGTTTGCTTCCGTTTTGGAAGACTCGGTTTTAGAGGAAAGTATAAAGGCAGGAA
AATTGGCAGATGGTTTATAG

Domains

Predicted by InterproScan.

• ComR tetratricopeptide (ComR_TPR) (75-292)

• Helix-turn-helix (HTH_3) (11-66)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comR	Streptococcus thermophilus LMG 18311	99.331	100	0.993
comR	Streptococcus thermophilus LMD-9	98.662	100	0.987
comR	Streptococcus salivarius strain HSISS4	94.649	100	0.946
comR	Streptococcus salivarius SK126	94.314	100	0.943
comR/comR2	Streptococcus sobrinus strain NIDR 6715-7	42.14	100	0.421
comR/comR1	Streptococcus sobrinus strain NIDR 6715-7	41.806	100	0.418