Detailed information    

insolico Bioinformatically predicted

Overview

Name   prx   Type   Regulator
Locus tag   E3C75_RS02290 Genome accession   NZ_CP038020
Coordinates   423958..424146 (+) Length   62 a.a.
NCBI ID   WP_111679075.1    Uniprot ID   -
Organism   Streptococcus thermophilus strain ATCC 19258     
Function   Inhibit ComR activation (predicted from homology)   
Competence regulation

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
Prophage 416521..425216 423958..424146 within 0


Gene organization within MGE regions


Location: 416521..425216
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  E3C75_RS02230 - 416521..417687 (-) 1167 WP_111679066.1 site-specific integrase -
  E3C75_RS11435 - 417829..418410 (-) 582 WP_084828737.1 helix-turn-helix transcriptional regulator -
  E3C75_RS02240 - 418560..418730 (+) 171 WP_084829211.1 transcriptional regulator -
  E3C75_RS02245 - 418983..419276 (+) 294 WP_111679067.1 hypothetical protein -
  E3C75_RS02250 - 419280..419474 (+) 195 WP_024704077.1 hypothetical protein -
  E3C75_RS02255 - 419488..419724 (+) 237 WP_024704076.1 hypothetical protein -
  E3C75_RS11440 - 419711..419923 (+) 213 WP_240899459.1 hypothetical protein -
  E3C75_RS02265 - 420060..420332 (+) 273 WP_023909303.1 MerR family transcriptional regulator -
  E3C75_RS02270 - 420347..421207 (+) 861 WP_111679069.1 primase alpha helix C-terminal domain-containing protein -
  E3C75_RS02275 - 421197..422702 (+) 1506 WP_111679071.1 DNA primase family protein -
  E3C75_RS02280 - 422999..423184 (+) 186 WP_111679073.1 hypothetical protein -
  E3C75_RS02285 - 423250..423477 (+) 228 WP_223899748.1 hypothetical protein -
  E3C75_RS02290 prx 423958..424146 (+) 189 WP_111679075.1 hypothetical protein Regulator
  E3C75_RS02295 - 424527..425216 (+) 690 WP_197709066.1 DUF3800 domain-containing protein -

Sequence

Protein


Download         Length: 62 a.a.        Molecular weight: 7133.08 Da        Isoelectric Point: 4.5837

>NTDB_id=351387 E3C75_RS02290 WP_111679075.1 423958..424146(+) (prx) [Streptococcus thermophilus strain ATCC 19258]
MLTYDEFKEAMDNGFIKGDTVQIVRKNGKIHDYVLDGERVEPHEILRLEKVSDIIKELGGDN

Nucleotide


Download         Length: 189 bp        

>NTDB_id=351387 E3C75_RS02290 WP_111679075.1 423958..424146(+) (prx) [Streptococcus thermophilus strain ATCC 19258]
ATGCTAACCTATGATGAATTTAAAGAGGCAATGGACAATGGTTTTATTAAAGGTGATACTGTCCAGATTGTCCGAAAGAA
TGGTAAGATCCATGACTACGTTTTAGACGGTGAACGAGTTGAGCCACACGAAATATTGAGATTAGAAAAAGTATCGGATA
TAATAAAAGAACTAGGCGGAGACAACTAA

Domains


No domain identified.



Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  prx Streptococcus pyogenes MGAS315

60.345

93.548

0.565
  prx Streptococcus pyogenes MGAS8232

59.322

95.161

0.565
  prx Streptococcus pyogenes MGAS315

57.627

95.161

0.548
  prx Streptococcus pyogenes MGAS315

56.897

93.548

0.532
  prx Streptococcus pyogenes MGAS315

74.419

69.355

0.516
  prx Streptococcus pyogenes MGAS315

65.957

75.806

0.5
  prx Streptococcus pyogenes MGAS315

65.957

75.806

0.5

Multiple sequence alignment