Detailed information    

insolico Bioinformatically predicted

Overview

Name   comR   Type   Regulator
Locus tag   GLO74_RS00745 Genome accession   NZ_CP046354
Coordinates   158273..158713 (+) Length   146 a.a.
NCBI ID   WP_001206582.1    Uniprot ID   -
Organism   Streptococcus pneumoniae strain 310     
Function   activate transcription of comX (predicted from homology)   
Competence regulation

Genomic Context

Location: 153273..163713
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  GLO74_RS00720 (GLO74_00740) - 153715..154845 (+) 1131 WP_197097184.1 N-acetyldiaminopimelate deacetylase -
  GLO74_RS00725 (GLO74_00745) - 154857..155396 (+) 540 WP_024477965.1 5-formyltetrahydrofolate cyclo-ligase -
  GLO74_RS00730 (GLO74_00750) - 155380..156057 (+) 678 WP_000658498.1 rhomboid family intramembrane serine protease -
  GLO74_RS00735 (GLO74_00755) galU 156124..157023 (-) 900 WP_024477964.1 UTP--glucose-1-phosphate uridylyltransferase GalU -
  GLO74_RS00740 (GLO74_00760) - 157045..158061 (-) 1017 WP_000415103.1 NAD(P)H-dependent glycerol-3-phosphate dehydrogenase -
  GLO74_RS00745 (GLO74_00765) comR 158273..158713 (+) 441 WP_001206582.1 helix-turn-helix domain-containing protein Regulator
  GLO74_RS00750 (GLO74_00770) - 158828..159280 (-) 453 Protein_147 transposase -
  GLO74_RS00755 (GLO74_00775) phoU 159321..159971 (-) 651 WP_001245781.1 phosphate signaling complex protein PhoU -
  GLO74_RS00760 (GLO74_00780) pstB 159986..160738 (-) 753 WP_000536449.1 phosphate ABC transporter ATP-binding protein PstB -
  GLO74_RS00765 (GLO74_00785) pstA 160740..161555 (-) 816 WP_000049768.1 phosphate ABC transporter permease PstA -
  GLO74_RS00770 (GLO74_00790) pstC 161548..162411 (-) 864 WP_000165892.1 phosphate ABC transporter permease subunit PstC -
  GLO74_RS00775 (GLO74_00795) - 162529..163404 (-) 876 WP_000669493.1 substrate-binding domain-containing protein -

Sequence

Protein


Download         Length: 146 a.a.        Molecular weight: 17758.49 Da        Isoelectric Point: 4.8659

>NTDB_id=350595 GLO74_RS00745 WP_001206582.1 158273..158713(+) (comR) [Streptococcus pneumoniae strain 310]
MREFGEKIKRLRLAKKISRSEFCGDESELSIRQLIRIENGESRPILTKLKYIAERLEVEDYKLMPSYIELDKEYLELKYF
LMRTPTYEDETIAQKKESVFDKIFEEYYDRLPEEERFIIPNYSYLALTNYTVQKLPEKLVEILSFW

Nucleotide


Download         Length: 441 bp        

>NTDB_id=350595 GLO74_RS00745 WP_001206582.1 158273..158713(+) (comR) [Streptococcus pneumoniae strain 310]
TTGCGAGAGTTTGGCGAAAAAATTAAAAGATTACGTTTGGCTAAAAAAATCAGTCGTTCAGAATTTTGTGGTGATGAGTC
TGAATTAAGTATCCGTCAATTAATTAGAATTGAAAATGGAGAATCCAGACCAATACTAACAAAGTTAAAATATATTGCTG
AACGTTTGGAGGTTGAAGATTACAAGTTGATGCCAAGTTATATAGAGTTGGATAAGGAATACCTAGAATTGAAGTATTTC
TTGATGAGGACTCCTACATACGAAGATGAAACTATCGCCCAAAAGAAAGAGAGTGTTTTTGATAAGATTTTTGAAGAGTA
TTATGATAGGCTACCTGAGGAAGAAAGATTTATCATCCCAAATTATTCATATCTGGCACTAACGAACTACACAGTTCAAA
AATTACCAGAAAAGCTAGTTGAAATACTGTCCTTCTGGTGA

Domains

Predicted by InterProScan.

ComR tetratricopeptide (ComR_TPR)

(72-119)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comR Streptococcus pyogenes MGAS8232

55

82.192

0.452
  comR Streptococcus pyogenes MGAS315

53.333

82.192

0.438
  comR Streptococcus mutans UA159

51.667

82.192

0.425
  comR Streptococcus infantarius subsp. infantarius ATCC BAA-102

53.636

75.342

0.404
  comR Streptococcus suis P1/7

46.61

80.822

0.377
  comR Streptococcus suis 05ZYH33

46.61

80.822

0.377
  comR Streptococcus suis D9

45.763

80.822

0.37
  comR/comR1 Streptococcus sobrinus strain NIDR 6715-7

46.491

78.082

0.363